Itaconate and Its Derivatives Repress Early Myogenesis In Vitro and In Vivo
Frontiers in Immunology, 2022 A Krebs cycle intermediate metabolite, itaconate, has gained attention as a potential antimicrobial and autoimmune disease treatment due to its anti-inflammatory effects.
Tae Seok Oh +5 more
doaj +1 more source
Coordinated actions of microRNAs with other epigenetic factors regulate skeletal muscle development and adaptation [PDF]
, 2017 Epigenetics plays a pivotal role in regulating gene expression in development, in response to cellular stress or in disease states, in virtually all cell types.
Adamo, Sergio +3 more
core +1 more source
Wnt signaling in myogenesis [PDF]
Trends in Cell Biology, 2012 The formation of skeletal muscle is a tightly regulated process that is critically modulated by Wnt signaling. Myogenesis is dependent on the precise and dynamic integration of multiple Wnt signals allowing self-renewal and progression of muscle precursors in the myogenic lineage.
Julia, von Maltzahn +3 more
openaire +2 more sources
Smad7:β-catenin Complex Regulates Myogenic Gene Transcription [PDF]
, 2019 Recent reports indicate that Smad7 promotes skeletal muscle differentiation and growth. We previously documented a non-canonical role of nuclear Smad7 during myogenesis, independent of its role in TGF-β signaling.
McDermott, John +2 more
core +1 more source
PLoS Biology, 2022 Skeletal muscle regeneration is essential for maintaining muscle function in injury and muscular disease. Myogenesis plays key roles in forming new myofibers during the process.
Xiao Chen Shi +8 more
doaj +1 more source
The action of obestatin in skeletal muscle repair: stem cell expansion, muscle growth, and microenvironment remodeling [PDF]
, 2015 The development of therapeutic strategies for skeletal muscle diseases, such as physical injuries and myopathies, depends on the knowledge of regulatory signals that control the myogenic process. The obestatin/GPR39 system operates as an autocrine signal
ADAMO, Sergio +16 more
core +1 more source
Membrane glucocorticoid receptors are localised in the extracellular matrix and signal through the MAPK pathway in mammalian skeletal muscle fibres [PDF]
, 2015 A number of studies have previously proposed the existence of glucocorticoid receptors on the plasma membrane of many cell types including skeletal muscle fibres.
Dietmar Steverding +8 more
core +1 more source
Journal of the American Society of Nephrology, 2010 After the basic shape of the mammalian ureter is established, its epithelia mature and a coat of smooth muscle cells differentiate around nascent urothelia. The ureter actively propels tubular fluid from the renal pelvis to the bladder, and this peristalsis, which starts in the fetal period, requires coordinated smooth muscle contraction.
C. M., Lye, Fasano, L., Woolf, A. S.
openaire +5 more sources
Changes in Expression of Proteolytic-Related Genes in Chick Myoblasts during Myogenesis
The Journal of Poultry Science, 2011 Changes in expression of proteolytic-related genes in chick myoblasts during myogenesis were investigated. Expression of MyoD and myogenin, as an index of differentiation, was regulated in chick myoblasts during myogenesis.
Kazuki Nakashima +2 more
doaj +1 more source
Role of microRNAs in myogenesis and their effects on meat quality in pig — A review [PDF]
Asian-Australasian Journal of Animal Sciences, 2020 The demand for food is increasing day by day because of the increasing global population. Therefore, meat, the easiest and largely available source of protein, needs to be produced in large amounts with good quality.
Ambreen Iqbal +8 more
doaj +1 more source