Results 201 to 210 of about 41,288 (271)

The Molecular Diagnosis of Myopathies: Integrating Genomic, Proteomic, and Pathological Insights Toward Precision Medicine

open access: yesClinical Genetics, Volume 110, Issue 1, Page 15-28, July 2026.
Advances in genomic, proteomic, and transcriptomic technologies are transforming the diagnosis of genetic myopathies. When integrated with traditional muscle pathology, multi‐omics approaches improve diagnostic yield, clarify disease mechanisms, and support more precise, mechanism‐based therapeutic strategies for patients with neuromuscular disorders ...
Ludmila Alem   +2 more
wiley   +1 more source

PRKG1 hinders myogenic differentiation and predicts response to AKT inhibitor ipatasertib in Rhabdomyosarcoma. [PDF]

open access: yesNat Commun
Prada E   +23 more
europepmc   +1 more source

Proteolysis at the extracellular matrix interface: Molecular architects and regulators in health and disease

open access: yesThe FEBS Journal, Volume 293, Issue 13, Page 3758-3787, July 2026.
The extracellular matrix (ECM) is a dynamic scaffold that orchestrates tissue architecture and cellular communication. A critical but underexplored interplay between proteases and cluster of differentiation molecules (CD) governs ECM turnover and directs cell fate.
David Jurnečka   +3 more
wiley   +1 more source

Ossifying spindled and epithelioid tumour: Expanding the clinical and morphologic spectrum of a recently described entity

open access: yesHistopathology, Volume 89, Issue 1, Page 163-173, July 2026.
Ossifying spindled and epithelioid tumour (OSET) can show unusual morphologic features, including minimal or absent peripheral ossification, eosinophil‐rich stroma, increased mitotic activity (≥5 mitotic figures per 10 high‐power fields), and necrosis.
Rayan M Sibira   +9 more
wiley   +1 more source

Multi‐Omics Landscape of Paraspinal Muscles in Spinal Muscular Atrophy With Scoliosis

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 13, July 2026.
ABSTRACT Most spinal muscular atrophy (SMA) patients develop severe scoliosis by late adolescence. Given that the paraspinal muscles—particularly the multifidus—are indispensable for maintaining spinal stability, their site‐specific multi‐omics characteristics in SMA remain insufficiently defined. Herein, integrated multi‐omics sequencing was performed
Zhen Wang   +4 more
wiley   +1 more source

Transcriptomic Insights Reveal PRTFDC1 as a Novel Regulator of Myogenic Differentiation in Sujiang Pig Satellite Cells. [PDF]

open access: yesVet Sci
Zhang L   +14 more
europepmc   +1 more source

Galvanic vestibular stimulation reveals disruption of ipsilesional brainstem pathways in hemiparetic stroke survivors

open access: yesExperimental Physiology, Volume 111, Issue 7, Page 3381-3397, 1 July 2026.
Abstract The spatiotemporal structure of muscle coordination emerges from the collaboration and competition among cortical, brainstem and spinal pathways onto motor neuron pools, each continuously shaped by task demands, limb position and descending tract integrity.
Angelo Bartsch‐Jiménez   +2 more
wiley   +1 more source

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