Results 181 to 190 of about 814,354 (242)

Neurophysiological subtyping of schizophrenia reveals a reproducible phenotype with temporoparietal circuit disruptions

General Psychiatry, Volume 39, Issue 5, October 2026.
ABSTRACT Background Heterogeneity in schizophrenia (SCZ) remains a major obstacle to the development of effective treatment. Aims This study aimed to identify reproducible neurobiological subtypes of SCZ using source‐localised, high‐density resting‐state electroencephalography (EEG) functional connectivity patterns.
Yue Ding, Xingxing Li, Junlin Liu, Guolin Jin, Weiwen Tian, Tifei Yuan, Wei Wu, Dongsheng Zhou   +7 more
wiley   +1 more source

MicroRNA–mRNA Networks in Skeletal Muscle of Tailored Pig Models for Dystrophinopathies

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 5, October 2026.
ABSTRACT Background Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD) are X‐linked dystrophinopathies caused by mutations in the dystrophin (DMD) gene. A common DMD‐causing mutation in humans is exon 52 deletion (DMDΔ52), which disrupts the reading frame and abolishes dystrophin expression.
Sarah Reschke, Alexander Graf, Frieder Hadlich, Florian Jaudas, Thomas Fröhlich, Michael Stirm, Nikolai Klymiuk, Stefan Krebs, Eckhard Wolf, Asghar Ali   +9 more
wiley   +1 more source

Genetic and Pharmacologic Inhibition of Myostatin Restores Muscle Mass in a Dynamin 2‐Related Centronuclear Myopathy Mouse Model

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 5, October 2026.
ABSTRACT Background Autosomal dominant centronuclear myopathy (ADCNM), most commonly caused by mutations in the dynamin 2 (DNM2) gene, is a rare congenital myopathy characterized by progressive muscle weakness and atrophy. Myostatin, a key negative regulator of skeletal muscle mass, has shown therapeutic potential in several models of neuromuscular ...
Durieux Anne‐Cécile, Arnould David, Velarde Mathias, Allibert Valentine, Paret Chloé, Debelley Quentin, Kizilkilic Esra, Chambon Sidney, Girard Emmanuelle, Collin Louise, Gensel Alexandre, Castells Josiane, Pasternack Aja, Bowen Maximilien, Morel Baptiste, Hourdé Christophe, Laurent Schaeffer, Ritvos Olli, Bitoun Marc, Mounier Rémi, Freyssenet Damien   +20 more
wiley   +1 more source

Skeletal Muscle–Derived Extracellular Vesicles During Eccentric and Concentric Exercise Promote Muscle Regeneration After Injury

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 5, October 2026.
ABSTRACT Background Skeletal muscle injuries significantly impair mobility and function, yet effective therapeutic interventions remain limited. Both eccentric exercise (EE) and concentric exercise (CE) promote muscle repair, but the underlying mechanisms are not fully understood.
Yining Zhou, Xiaoyan Shao, Pan Zhang, Jiaquan Lin, Xiang Chen, Xueying An, Zhuoying Jiang, Haosheng Wang, Depeng Fang, Yansi Xian, Bin Liu, Tao Shen, Ying Chen, Keran Li, Hongpeng Liu, Ying Li, Qing Jiang, Baosheng Guo   +17 more
wiley   +1 more source

PAX3 mutant mesoangioblasts are defective in myogenic differentiation

, 2005
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openaire   +2 more sources

Brown Adipose Tissue: Molecular Mechanisms of Regulation, Physiological Functions, and Therapeutic Targets

MedComm, Volume 7, Issue 10, October 2026.
This review systematically covers three core dimensions of brown adipose tissue (BAT): multilayered regulatory mechanisms governing brown adipocyte differentiation and phenotypic identity, physiological functions and signaling pathways in mediating thermogenesis and systemic metabolic crosstalk between BAT and multiple organs, and emerging clinical in ...
Xiaoli Deng, Yuanyuan Shen, Ying Sun, Lu Lu, Chongkui Sun   +4 more
wiley   +1 more source

Aging of Skeletal Muscle: From Molecular Mechanisms to Therapeutic Interventions

MedComm, Volume 7, Issue 10, October 2026.
Skeletal muscle aging is driven by coordinated local breakdown across myofibers, stem and stromal cells, immune and vascular compartments, and neuromuscular control. These mechanisms promote mitochondrial dysfunction, inflammation, senescence, impaired regeneration, fibrosis, myosteatosis, denervation, and functional decline.
Ting Liu, Yaomin Hu
wiley   +1 more source

Effects of Tributyltin Chloride on Human Neuronal Differentiation and Mice Brain Development

Environmental Toxicology, Volume 41, Issue 10, Page 906-921, October 2026.
ABSTRACT According to the developmental origins of health and disease hypothesis, perinatal exposure to an environmental toxicant during the development of the nervous system could cause a permanent cellular modification that may promote the appearance of neurodegenerative diseases at an older age.
Ester López‐Gallardo, Patricia Meade, Irene Jiménez‐Salvador, Carmen Hernández‐Ainsa, Eldris Iglesias, Alba Pesini, Nuria Garrido‐Pérez, Sonia Emperador, David Pacheu‐Grau, Pilar Bayona‐Bafaluy, Eduardo Ruiz‐Pesini   +10 more
wiley   +1 more source

Secondary cartilage in the murine medial pterygoid plate has a critical role in the pathfinding of the tensor veli palatini

Journal of Anatomy, Volume 249, Issue 4, Page 759-768, October 2026.
The development of the medial pterygoid plate (MPP) is followed in mouse embryos, highlighting its neural crest origin and complex development via both endochondral and membranous ossification. Using transgenic mice, the secondary cartilage of the MPP is shown to direct the path of the tensor veli palatini.
Luke A. Barlow, Emi Nomura, Abigail S. Tucker   +2 more
wiley   +1 more source

Efficacy of Myofascial Release Therapy and Related Soft‐Tissue Techniques for Pain in Temporomandibular Disorders: A Systematic Review of Randomized Controlled Trials

Journal of Oral Rehabilitation, Volume 53, Issue 10, Page 1972-1984, October 2026.
This systematic review evaluated the effectiveness of myofascial release therapy (MFR) for pain management in patients with myogenous temporomandibular disorders (TMD). Seven randomized controlled trials involving patients diagnosed according to RDC/TMD or DC/TMD criteria were included.
Martina Ferrillo, Dario Calafiore, Alfredo De Rosa, Ambra Sedran, Umile Giuseppe Longo, Michele Vecchio, Antonio Ammendolia, Nicola Scotti, Amerigo Giudice, Alessandro de Sire   +9 more
wiley   +1 more source