Results 191 to 200 of about 64,746 (288)

Ageing‐Associated Dysregulation of Myogenic Differentiation in Inclusion Body Myositis

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 3, June 2026.
ABSTRACT Skeletal muscle is a postmitotic tissue dependent on a complex and tightly regulated regeneration process involving numerous intracellular and extracellular factors, including myogenic regulatory factors (MRFs), cytokines and myokines. Quiescent satellite cells are activated by physiological stimuli, injury or other traumatic insults for the ...
Geert M. de Vries, Willem De Ridder, Jonathan Baets   +2 more
wiley   +1 more source

Hybrid 3D-printed/electrospun scaffolds drive myogenic differentiation of mesenchymal stem cells (MSCs). [PDF]

Sci Rep
Pisani S, Marconi S, Mauri V, Rossetti B, Evangelista A, Bruni G, Benazzo M, Auricchio F, Conti B.   +8 more
europepmc   +1 more source

Klhl31 is assocaited with skeletal myogenesis and its expression is regulated by myogenic signals and Myf-5 [PDF]

, 2009
Adams, Alaa Abou-Elhamd, Alvares, Andrea Münsterberg, Angers, Boardman, Borello, Bork, Borycki, Borycki, Borycki, Brent, Buckingham, Christ, Delfini, Dietrich, Dietrich, Fan, Geetha-Loganathan, Gros, Hamburger, Hara, Hollyday, Marcelle, McDermott, Münsterberg, Münsterberg, Oliver Cooper, Pownall, Pownall, Scaal, Schmidt, Schmidt, Schubert, Smith, Stogios, Stogios, Summerbell, Sweetman, Tajbakhsh, Wu, Xue, Yu   +42 more
core   +1 more source

Elevated Circulating Ceramides 18:0 and 24:1 as a Risk Factor for Sarcopenia: In Vitro, Animal, and Clinical Evidence

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 3, June 2026.
ABSTRACT Background Ceramides have garnered considerable attention as pro‐aging bioactive lipids implicated in both metabolic dysfunction and musculoskeletal decline. Among these, C18:0 and C24:1 ceramides may play a role in the pathophysiology of sarcopenia, a key manifestation of age‐related deterioration.
So Jeong Park, Ji Yeon Baek, Shibo Wei, Jin Young Lee, Yuna Lee, Sang‐Hoon Lee, Il‐Young Jang, Hyuk Sakong, Hyun Ju Yoo, Hee‐Won Jung, Eunju Lee, Su Jung Kim, Yunju Jo, Kyunggon Kim, Dongryeol Ryu, Beom‐Jun Kim   +15 more
wiley   +1 more source

RNA-seq analysis reveals a positive role for NGF in the myogenic differentiation of bovine skeletal muscle satellite cells. [PDF]

Front Genet
Li X, Zhao Z, Cao Y, Zhao Y, Qin L.
europepmc   +1 more source

Atrophic Skeletal Muscle‐Derived Extracellular Vesicles Transfer miR‐125a‐5p to Inhibit Bone Formation in Osteoporosis during Aging

Advanced Science, Volume 13, Issue 25, 4 May 2026.
A muscle‐bone endocrine pathway in aging is revealed in which extracellular vesicles released from atrophic skeletal muscle (Aged‐SKM‐EVs) inhibit bone formation. These EVs deliver miR‐125a‐5p to osteoblasts, thereby suppressing the SIRT7‐Sp7 signaling axis and osteogenic differentiation.
Xiaoyan Shao, Pan Zhang, Zhidan Fan, Jiaquan Lin, Xiang Chen, Na Liu, Wang Gong, Yi He, Yining Zhou, Tianshu Shi, Yong Shi, Yuze Ma, Wentian Gao, Haosheng Wang, Depeng Fang, Chengzhi Wang, Wenshu Wu, Wenjin Yan, Jianghui Qin, Dongyang Chen, Haiguo Yu, Qing Jiang, Baosheng Guo   +22 more
wiley   +1 more source

Development of Emerin mRNA Lipid Nanoparticles to Rescue Myogenic Differentiation. [PDF]

Int J Mol Sci
Marano N, Guner LE, Riley RS, Holaska JM.   +3 more
europepmc   +1 more source

The Age‐Dependent Resident Myonuclear Multi‐Omic Response to an Acute Skeletal Muscle Hypertrophic Stimulus in Mice

Advanced Science, Volume 13, Issue 25, 4 May 2026.
Resident myonuclei are the molecular “control centers” for large multinuclear muscle fibers. It is presumed that, with aging, these control centers become compromised and contribute to delayed or blunted muscle adaptive potential. This study is a detailed roadmap that exposes how young versus aged myonuclei respond to a hypertrophic loading stimulus ...
Pieter J. Koopmans, Ronald G. Jones III, Ana Regina Cabrera, Francielly Morena, Nicholas P. Greene, John J. McCarthy, Ahmed Ismaeel, Yuan Wen, Kevin A. Murach   +8 more
wiley   +1 more source

PRKG1 hinders myogenic differentiation and predicts response to AKT inhibitor ipatasertib in Rhabdomyosarcoma. [PDF]

Nat Commun
Prada E, Táboas P, Andrades E, Gómez-González S, Mateo-Lozano S, Cebria-Xart A, Berenguer-Molins P, Perera-Bel J, Arcon JP, Saen-Oon S, Díaz L, Gay M, Folch-I-Casanovas I, Odena A, Vilaseca M, Rovira Q, Garcia-Gerique L, Rodriguez E, Rovira C, Rodrigues G, Carcaboso AM, Avgustinova A, Hernández-Muñoz I, Mora J.   +23 more
europepmc   +1 more source

Immune‐Related Polyradiculoneuropathy Associated With Immune Checkpoint Inhibitors: A Comprehensive Case Series

Brain and Behavior, Volume 16, Issue 5, May 2026.
ABSTRACT Objective Immune‐related polyradiculoneuropathy (irPRN) is a rare but potentially severe neurological adverse event secondary to immune checkpoint inhibitors (ICIs), closely resembling Guillain–Barré syndrome. This study aims to characterize the clinical presentation, neurophysiological findings, therapeutic strategies, and clinical outcomes ...
A. Llauradó, E. Lainez, H. Ariño, M. Gratacòs‐Viñola, J. L. Seoane, M. Roca‐Herrera, J. L. Restrepo‐Vera, D. Sanchez‐Tejerina, N. Raguer, R. Juntas‐Morales   +9 more
wiley   +1 more source