Results 191 to 200 of about 41,288 (271)

C-peptide promotes myogenic differentiation in vitro and low serum levels are associated with sarcopenia in adults and the elderly. [PDF]

open access: yesJ Transl Med
Ferro Y   +12 more
europepmc   +1 more source

A living biobank of sarcoma patient‐derived cell cultures reveals multi‐omic and functional insights that capture disease heterogeneity

open access: yesClinical and Translational Medicine, Volume 16, Issue 7, July 2026.
Preclinical models for sarcoma that preserve tumour biology are urgently needed to advance mechanistic understanding and functional precision oncology. 29 early‐passage patient‐derived sarcoma cell (PDC) cultures from 19 patients, representing 11 sarcoma subtypes were established and extensively characterized.
Stefanie Gijsels   +19 more
wiley   +1 more source

Biphenotypic Sinonasal Sarcoma With a Novel PAX3::MAML2 Fusion

open access: yesGenes, Chromosomes and Cancer, Volume 65, Issue 7, July 2026.
ABSTRACT Biphenotypic sinonasal sarcoma (BSNS) is a rare, low‐grade spindle cell sarcoma of the sinonasal tract. It is characterized by dual neural and myogenic differentiation and classically shows fusions involving PAX3. MAML3, a co‐activator in the Notch signaling pathway, is the most common fusion partner of PAX3.
Mayu Uemura   +4 more
wiley   +1 more source

Edible Sulfonated Soy Protein Microcarriers for Cultivated Meat Cell Expansion

open access: yesJournal of Biomedical Materials Research Part A, Volume 114, Issue 7, July 2026.
ABSTRACT Microcarriers are essential in large‐scale cell expansion for applications such as cultivated meat but are typically composed of non‐edible materials, requiring additional cell retrieval steps. The ability to incorporate microcarriers into a final product would reduce cost and potentially add nutritional value.
Andrea C. Filler   +4 more
wiley   +1 more source

Hybrid 3D-printed/electrospun scaffolds drive myogenic differentiation of mesenchymal stem cells (MSCs). [PDF]

open access: yesSci Rep
Pisani S   +8 more
europepmc   +1 more source

Vitamin‐Responsive Disorders: From Molecular Basis to Clinical Presentation and Therapy

open access: yesJournal of Inherited Metabolic Disease, Volume 49, Issue 4, July 2026.
ABSTRACT Vitamin‐dependent cofactors are essential for numerous metabolic reactions, and defects affecting their uptake, conversion, utilisation, or regeneration constitute a heterogeneous group of inherited metabolic disorders (IMDs). Although dietary vitamin intake is sufficient to sustain coenzyme synthesis in healthy individuals, it is insufficient
Cécile Acquaviva   +5 more
wiley   +1 more source

Unraveling the spatial landscape of dystrophinopathies: a transcriptomic approach to Becker and Duchenne muscular dystrophies

open access: yesThe Journal of Pathology, Volume 269, Issue 3, Page 363-380, July 2026.
Abstract Dystrophinopathies are caused by pathogenic variants in the DMD gene, resulting in partial (Becker) or complete loss (Duchenne) of dystrophin. Becker (BMD) and Duchenne muscular dystrophy (DMD) are characterized by progressive muscle wasting, fatty replacement, fibrosis, and loss of function.
Laura GM Heezen   +14 more
wiley   +1 more source

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