C-peptide promotes myogenic differentiation in vitro and low serum levels are associated with sarcopenia in adults and the elderly. [PDF]
Ferro Y +12 more
europepmc +1 more source
Preclinical models for sarcoma that preserve tumour biology are urgently needed to advance mechanistic understanding and functional precision oncology. 29 early‐passage patient‐derived sarcoma cell (PDC) cultures from 19 patients, representing 11 sarcoma subtypes were established and extensively characterized.
Stefanie Gijsels +19 more
wiley +1 more source
Biphenotypic Sinonasal Sarcoma With a Novel PAX3::MAML2 Fusion
ABSTRACT Biphenotypic sinonasal sarcoma (BSNS) is a rare, low‐grade spindle cell sarcoma of the sinonasal tract. It is characterized by dual neural and myogenic differentiation and classically shows fusions involving PAX3. MAML3, a co‐activator in the Notch signaling pathway, is the most common fusion partner of PAX3.
Mayu Uemura +4 more
wiley +1 more source
Pharmacological Inhibition of N-terminal methyltransferase 1 promotes myogenic differentiation and muscle regeneration in a mouse model of Duchenne muscular dystrophy. [PDF]
Zhang H +5 more
europepmc +1 more source
PAX3 mutant mesoangioblasts are defective in myogenic differentiation
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openaire +2 more sources
Edible Sulfonated Soy Protein Microcarriers for Cultivated Meat Cell Expansion
ABSTRACT Microcarriers are essential in large‐scale cell expansion for applications such as cultivated meat but are typically composed of non‐edible materials, requiring additional cell retrieval steps. The ability to incorporate microcarriers into a final product would reduce cost and potentially add nutritional value.
Andrea C. Filler +4 more
wiley +1 more source
Hybrid 3D-printed/electrospun scaffolds drive myogenic differentiation of mesenchymal stem cells (MSCs). [PDF]
Pisani S +8 more
europepmc +1 more source
Vitamin‐Responsive Disorders: From Molecular Basis to Clinical Presentation and Therapy
ABSTRACT Vitamin‐dependent cofactors are essential for numerous metabolic reactions, and defects affecting their uptake, conversion, utilisation, or regeneration constitute a heterogeneous group of inherited metabolic disorders (IMDs). Although dietary vitamin intake is sufficient to sustain coenzyme synthesis in healthy individuals, it is insufficient
Cécile Acquaviva +5 more
wiley +1 more source
Development of Emerin mRNA Lipid Nanoparticles to Rescue Myogenic Differentiation. [PDF]
Marano N +3 more
europepmc +1 more source
Abstract Dystrophinopathies are caused by pathogenic variants in the DMD gene, resulting in partial (Becker) or complete loss (Duchenne) of dystrophin. Becker (BMD) and Duchenne muscular dystrophy (DMD) are characterized by progressive muscle wasting, fatty replacement, fibrosis, and loss of function.
Laura GM Heezen +14 more
wiley +1 more source

