Results 31 to 40 of about 86,817 (243)

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Comparison of Creatine Kinase Activity and Myoglobin Blood Level in Acute Myocardial Infarction Patients

Biomolecules & Biomedicine, 2008
The aim of this prospective study was to evaluate and compare the relative increase of serum myoglobin level and total creatine kinase(CK) activity in acute myocardial infarction (AMI) patients (n=36). We measured serial changes in total CK activity and 
Sabaheta Hasić, Radivoj Jadrić, Emina Kiseljaković, Jovan Radovanović, Mira Winterhalter-Jadrić   +4 more
doaj   +1 more source

Oxidation of Native and Modified Hemoglobin and Myoglobin by Sodium Nitrate. Effect of Inositol Hexaphosphate [PDF]

, 1981
Native and modified hemoglobin, myoglobin and a and phemoglobin subunits were oxidized by sodium nitrite at pH 6. The experiments were carried out under oxy and deoxy conditions with and without inositol hexaphosphate (IHP).
Mansouri, Ali
core   +2 more sources

Solvent-induced organization: A physical model of folding myoglobin

, 1994
The essential features of the in vitro refolding of myoglobin are expressed in a solvable physical model. Alpha helices are taken as the fundamental collective coordinates of the system, while the refolding is assumed to be mainly driven by solvent ...
Acampora, Allen, Anfinsen, Arnold, Arutyunyan, Bashford, Ben-Naim, Callaway, Cantor, Chothia, Christenson, Claesson, Cohen, Creighton, David J. E. Callaway, Dickerson, Dill, Eisenberg, Evans, Franks, Gardiner, Griko, Gruenewald, Hughson, Hughson, Hughson, Israelachvili, Jaenicke, Jennings, Jones, Jorgensen, Kuczera, Kuwajima, Levinthal, Levitt, Levitt, Levitt, McCammon, Nicholls, Nishikawa, Nozaki, Pangali, Pangali, Podgornik, Potter, Pratt, Privalov, Ptitsyn, Ptitsyn, Puett, Rao, Saito, Shaknovich, Sharp, Shen, Shin, Shin, Smith, Stillinger, Stouten, Tanford, Waltho, Warshel, Watson, Wax, Wolfenden, Zimmerman   +66 more
core   +2 more sources

Engineering tyrosine-based electron flow pathways in proteins: The case of aplysia myoglobin [PDF]

, 2012
Tyrosine residues can act as redox cofactors that provide an electron transfer ("hole-hopping") route that enhances the rate of ferryl heme iron reduction by externally added reductants, for example, ascorbate.
Alayash A. I., Alayash A. I., Aubert C., Bolognesi M., Brandon J. Reeder, Chris E. Cooper, Dimitri A. Svistunenko, Egmond M. R., Ekberg M., Ekberg M., Gray H. B., Holt S., Lardinois O. M., McLeod L. L., Michael T. Wilson, Moore K. P., Natanson C., Nilges M. J., Peisach J., Reece S. Y., Reeder B. J., Reeder B. J., Reeder B. J., Reeder B. J., Reeder B. J., Reeder B. J., Reeder B. J., Rogers M. S., Rova U., Rova U., Seyedsayamdost M. R., Shih C., Silaghi-Dumitrescu R., Stubbe J., Svistunenko D. A., Svistunenko D. A., Svistunenko D. A., Thompson M. K., Wilbur D. J., Yee C. S.   +39 more
core   +1 more source

Implementation of Drug‐Induced Rhabdomyolysis and Acute Kidney Injury in Microphysiological System

Advanced Functional Materials, EarlyView.
A modular Muscle–Kidney proximal tubule‐on‐a‐chip integrates 3D skeletal muscle and renal proximal tubule tissues to model drug‐induced rhabdomyolysis and acute kidney injury. The coculture system enables dynamic tissue interaction, functional contraction monitoring, and quantification of nephrotoxicity, revealing drug side effect‐induced metabolic ...
Jaesang Kim, Zhuo Feng Lee, Gi‐Dong Sim, Sejoong Kim, Jessie S. Jeon   +4 more
wiley   +1 more source

Fractal Analysis of Protein Potential Energy Landscapes

, 1998
The fractal properties of the total potential energy V as a function of time t are studied for a number of systems, including realistic models of proteins (PPT, BPTI and myoglobin).
A. E. García, B. B. Mandelbrot, B. Dubuc, D. A. Hamburger-Lidar, D. A. Lidar, D. Thirumalai, D. Thirumalai, H. Frauenfelder, J. C. Russ, J. E. Straub, K. D. Ball, K. Falconer, M. Doi, P. G. Wolynes, P. Pfeifer, R. B. Gerber, R. Czerminski, R. Elber, R. Elber   +18 more
core   +1 more source

Probabilistic classification of acute myocardial infarction from multiple cardiac markers [PDF]

, 2008
Logistic regression and Gaussian mixture model (GMM) classifiers have been trained to estimate the probability of acute myocardial infarction (AMI) in patients based upon the concentrations of a panel of cardiac markers.
C Bishop, F Dombal de, F Fesmire, F Fesmire, George W. Irwin, H Selker, J Ellenuis, J Habbema, J Habbema, J Habbema, J Hanley, J Hilden, J Hilden, John V. Lamont, L Goldman, L Goldman, M Pozen, Paul C. Wilson, Robert F. Harrison, T Groth, W Tierney   +20 more
core   +1 more source

Oxygen and ROS Delivery for Infected Wound Healing and Future Prospects

Advanced Healthcare Materials, EarlyView.
Bacterial infection is a major driver of delayed wound healing and postsurgical readmissions; with rising antibiotic resistance, solid peroxide–releasing biomaterials offer sustained delivery of ROS/O2 for antimicrobial control and microenvironmental modulation.
Ayden Watt, Chably Rachella, Charlotte Jaloux, Joshua Vorstenbosch, Adam Hart, Michael Tanzer, Geraldine Merle, Jake Barralet   +7 more
wiley   +1 more source

Serum Myoglobin Is Associated With Postoperative Acute Kidney Injury in Stanford Type A Aortic Dissection

Frontiers in Medicine, 2022
BackgroundThe correlation between rhabdomyolysis and postoperative acute kidney injury has been reported in several surgical procedures. As a good predictor of rhabdomyolysis-related acute kidney injury, an elevated serum myoglobin level was often ...
Chen Yang, Peng Hou, Dongxu Wang, Zhenguo Wang, Weixun Duan, Jincheng Liu, Shiqiang Yu, Feng Fu, Zhenxiao Jin   +8 more
doaj   +1 more source