Femtosecond X-ray emission study of the spin cross-over dynamics in haem proteins
, 2020 In haemoglobin (consisting of four globular myoglobin-like subunits), the change from the low-spin (LS) hexacoordinated haem to the high spin (HS) pentacoordinated domed form upon ligand detachment and the reverse process upon ligand binding, represent ...
Bacellar, Camila +28 more
core +1 more source
MSM/RD: Coupling Markov state models of molecular kinetics with reaction-diffusion simulations [PDF]
, 2018 Molecular dynamics (MD) simulations can model the interactions between macromolecules with high spatiotemporal resolution but at a high computational cost. By combining high-throughput MD with Markov state models (MSMs), it is now possible to obtain long-
De Sancho, David +4 more
core +2 more sources
The Use of Coupled Plasma Filtration Adsorption in Traumatic Rhabdomyolysis
Case Reports in Critical Care, 2017 Severe musculoskeletal injuries induce the release of sarcoplasmic elements such as muscle enzymes, potassium, and myoglobin in the systemic circulation. The circulating myoglobin damages the glomerulus and renal tubules.
Mario Pezzi +7 more
doaj +1 more source
The Relationship between Obesity and Oxidative Stress and Cardiac Markers
Medicine Science, 2015 Obesity is one of the most even leading issue for the last era but however the reasons for this epidemic could not been explained clearly yet. We aimed to investigate the relationship between obesity, and myoglobin and homocysteine in means of cardiac ...
Pinar Baki Unver +4 more
doaj +1 more source
Myoglobin-Catalyzed C-H Functionalization of Unprotected Indoles.
Angewandte Chemie, 2018 Functionalized indoles are recurrent motifs in bioactive natural products and pharmaceuticals. While transition metal-catalyzed carbene transfer has provided an attractive route to afford C3-functionalized indoles, these protocols are viable only in the ...
David A Vargas +3 more
semanticscholar +1 more source
Top-Down Mass Analysis of Protein Tyrosine Nitration: Comparison of Electron Capture Dissociation with “Slow-Heating” Tandem Mass Spectrometry Methods [PDF]
, 2010 Tyrosine nitration in proteins is an important post-translational modification (PTM) linked to various pathological conditions. When multiple potential sites of nitration exist, tandem mass spectrometry (MS/MS) methods provide unique tools to locate the ...
Cooper, Helen J. +2 more
core +2 more sources
Formation of Myoglobin Corona at Polymer Microparticles
Colloids and Interfaces, 2021 Adsorption of myoglobin molecules at negatively charged polystyrene microparticles was studied using the dynamic light scattering (DLS), electrophoresis (LDV) and the solution depletion method involving atomic force microscopy (AFM).
Zbigniew Adamczyk +1 more
doaj +1 more source
An investigation into the feasibility of myoglobin-based single-electron transistors
, 2012 Myoglobin single-electron transistors were investigated using nanometer- gap platinum electrodes fabricated by electromigration at cryogenic temperatures. Apomyoglobin (myoglobin without heme group) was used as a reference.
Bendall D S +9 more
core +1 more source
Myoglobin induces mitochondrial fusion, thereby inhibiting breast cancer cell proliferation
Journal of Biological Chemistry, 2019 Myoglobin is a monomeric heme protein expressed ubiquitously in skeletal and cardiac muscle and is traditionally considered to function as an oxygen reservoir for mitochondria during hypoxia.
Andrea Braganza +9 more
semanticscholar +1 more source
Solvent-induced organization: A physical model of folding myoglobin
, 1994 The essential features of the in vitro refolding of myoglobin are expressed in a solvable physical model. Alpha helices are taken as the fundamental collective coordinates of the system, while the refolding is assumed to be mainly driven by solvent ...
Acampora +66 more
core +2 more sources