Results 11 to 20 of about 150,878 (313)

Genome-wide analysis points to roles for extracellular matrix remodeling, the visual cycle, and neuronal development in myopia [PDF]

open access: yes, 2012
Myopia, or nearsightedness, is the most common eye disorder, resulting primarily from excess elongation of the eye. The etiology of myopia, although known to be complex, is poorly understood. Here we report the largest ever genome-wide association study (
Do, Chuong B.   +6 more
core   +5 more sources

Anterior Segment Characteristics of Eyes with Anterior Chamber Depth Less than 2.8 mm and Axial Length Greater than 25 mm

open access: yesOphthalmology and Therapy, 2023
Introduction This study aimed to investigate anterior segment parameters of eyes, with anterior chamber depth (ACD) less than 2.8 mm and axial length greater than 25.0 mm.
Lingling Niu   +5 more
doaj   +1 more source

Current trends among pediatric ophthalmologists to decrease myopia progression—an international perspective [PDF]

open access: yes, 2018
Purpose To explore what the current worldwide preferred practice patterns of pediatric ophthalmologists are to decrease myopia progression among their patients.
Farzavandi, Sonal K.   +5 more
core   +1 more source

Ocular Refraction at Birth and Its Development During the First Year of Life in a Large Cohort of Babies in a Single Center in Northern Italy [PDF]

open access: yes, 2020
The purpose of this study was to investigate refraction at birth and during the first year of life in a large cohort of babies born in a single center in Northern Italy.
Bartollino S.   +7 more
core   +1 more source

Two-year outcome of an eye that underwent hyperopic LASIK following inadvertent myopic SMILE lenticule in situ implantation

open access: yesBMC Ophthalmology, 2019
Background This report describes a case in which hyperopic femtosecond laser-assisted in situ keratomileusis (FS-LASIK) was performed following small incision lenticule extraction (SMILE) lenticule in situ implantation.
Jing Zhao   +7 more
doaj   +1 more source

Human tear proteome dataset in response to daily wear of water gradient contact lens using SWATH-MS approach

open access: yesData in Brief, 2021
Water Gradient Contact Lens (WGCL) is a new generation material that combines the benefits of Silicone hydrogel (SiHy) and traditional hydrogel contact lenses by modifying the materials between the core and the surface.
Jimmy Ka-Wai Cheung   +8 more
doaj   +1 more source

Time outdoors and the prevention of myopia [PDF]

open access: yes, 2015
Recent epidemiological evidence suggests that children who spend more time outdoors are less likely to be, or to become myopic, irrespective of how much near work they do, or whether their parents are myopic.
Ashby, Regan S.   +3 more
core   +1 more source

Myopia and defocus: the current understanding [PDF]

open access: yes, 2011
The current theories relating to the development and progression of myopia are related to exposure of the eye to hyperopic defocus. This paper discusses these theories and the large body of recent research investigating the evidence behind them.
Day, Mhairi, Duffy, Lorraine
core   +1 more source

Metabolic memory in mitochondrial oxidative damage triggers diabetic retinopathy

open access: yesBMC Ophthalmology, 2018
Background Diabetic retinopathy (DR) is a microvascular complication induced by high blood glucose. This study was conducted to investigate the effect of metabolic memory on mitochondrial oxidative damage-induced DR. Methods Rat retinal endothelial cells
Zhaoge Wang   +5 more
doaj   +1 more source

Pre-treatment With Ranibizumab Aggravates PDT Injury and Alleviates Inflammatory Response in Choroid-Retinal Endothelial Cells

open access: yesFrontiers in Cell and Developmental Biology, 2020
Polypoidal choroidal vasculopathy (PCV) is the predominant subtype of exudative age-related macular degeneration in Asians. Although photodynamic therapy (PDT) is widely used for PCV treatment, its long-term beneficial effects are unsatisfactory ...
Yang Liu   +11 more
doaj   +1 more source

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