Results 101 to 110 of about 287,774 (303)

Determination of the Maximum Velocity of Filaments in the in vitro Motility Assay

Frontiers in Physiology, 2019
The in vitro motility assay (IVMA) is a powerful tool commonly used in basic muscle research and for drug screenings with the aim to find treatment options for neuromuscular disorders.
Nasrin Bopp, Nasrin Bopp, Lisa-Mareike Scheid, Rainer H. A. Fink, Karl Rohr   +4 more
doaj   +1 more source

An Opto‐Actuated Hydrogel for Cell Mechanoactuation and Real‐Time Force Monitoring

Advanced Science, EarlyView.
Researchers developed a mechanoactuated hydrogel interface where nanomachines exert forces on adhesion receptors and allow monitoring of traction force responses in real time. They demonstrate reversible talin recruitment, enhanced F‐actin polymerization, and a reduction in cell traction force when force is locally applied to focal adhesions of ...
Rinku Kumar, Marc A. Fernandez‐Yague, Adrien Bessaguet, Hosoowi Lee, Nicolas Giuseppone, Andrés J. García, Aránzazu del Campo   +6 more
wiley   +1 more source

Isolation and identification of actin-binding proteins in Plasmodium falciparum by affinity chromatography

Memorias do Instituto Oswaldo Cruz, 2000
The invasion of the erythrocyte by Plasmodium falciparum depends on the ability of the merozoite to move through the membrane invagination. This ability is probably mediated by actin dependent motors.
Claudia Forero, Moisés Wasserman
doaj   +1 more source

Biohybrid Tendons Enhance the Power‐to‐Weight Ratio and Modularity of Muscle‐Powered Robots

Advanced Science, EarlyView.
Biohybrid robots powered by skeletal muscle actuators are capable of dynamically adapting to environmental cues. This study takes inspiration from native muscle–tendon architecture by leveraging tough hydrogels as synthetic tendons for muscle actuators to enhance the power‐to‐weight ratio and modularity of biohybrid machines.
Nicolas Castro, Ronald Heisser, Maheera Bawa, Bastien Aymon, Sarah Wu, Annika Marschner, Sonika Kohli, Angel Bu, Laura Rosado, Martin Culpepper, Xuanhe Zhao, Ritu Raman   +11 more
wiley   +1 more source

Unraveling the Morphological and Functional Maturation Mechanisms Underlying Human Neural Development Using iPSCs‐Derived Neuronal Model

Advanced Science, EarlyView.
Using human induced pluripotent stem cells (hiPSCs)‐derived neuronal model, Tian and colleagues reveal that voltage‐gated calcium channels Cav1.2 and Cav1.3, and their mediated calcium ion influx, are essential for early morphogenesis of human neuronal development, while ECEL1 underlies human neuronal functional developmental maturation through CALM3 ...
Yue Tian, Yi‐Chun Ou, Zi‐Xian Zhang, Jie Cai, Si‐Qing Cai, Guo‐Gang Xing   +5 more
wiley   +1 more source

Unique Contractile and Structural Protein Expression in Dog Ileal Inner Circular Smooth Muscle [PDF]

, 2009
This study was designed to test the hypothesis that there is heterogeneous expression of contractile and structural proteins between the smooth muscle cells (SMCs) in the inner and outer circular muscle (ICM and OCM) layers of the ileum ...
Eddinger, Thomas J.
core   +1 more source

Possible origins of macroscopic left-right asymmetry in organisms

, 2012
I consider the microscopic mechanisms by which a particular left-right (L/R) asymmetry is generated at the organism level from the microscopic handedness of cytoskeletal molecules.
A. Tamada, A. Varma, A. Vilfan, A.M. Heacock, A.R. Palmer, C. Ambrose, C. Arrieumerlou, C. McManus, C. Pohl, C.H. Wiggins, C.L. Henley, C.R. Cowan, C.S. Peskin, C.W. Wolgemuth, Christopher L. Henley, D. Vavylonis, D.S. Adams, D.W. Ehrhardt, E. Ben-Jacob, E. Ben-Jacob, E. Kawamura, E.C. Eren, E.C. Eren, E.E. Deinum, F. Ziebert, F.C. Frank, G. Salbreux, G.M. Grason, G.O. Wasteneys, H. Hamada, H.F. Romijn, I. Mabuchi, J. Chan, J. Chan, J. Cooke, J. Gore, J. Hagmann, J. Salje, J. Xu, J.A. Åström, J.F. Allard, J.F. Allard, J.F. Beausang, J.H.E. Cartwright, K. Taniguchi, L.F. Jones, L.Q. Wan, M. Levin, M. Levin, M. Levin, M. Mayer, M.E. Halpern, M.L. Manning, M.P. Wold, M.V. Danilchik, M.V. Thompson, M.Y. Ali, N. Hirokawa, N. Morone, N.A. Brown, N.H. Mendelson, N.H. Mendelson, P. Spéder, P. Spéder, R. Dixit, R. Kawamura, R. Kuroda, R.D. Kamien, R.D. Preston, R.J. Hawkins, R.J. Poole, R.M. Figge, S. Aw, S. Hozumi, S. Nonaka, S. Nonaka, S. Thitamadee, S. Wang, S.H. Tindemans, S.L. Shaw, S.S. Andrews, T. Hashimoto, T. Ishida, T. Kamasaki, T. Lionnet, T. Nishizaka, T. Okumura, T. Sun, T.-H. Chuan, V.A. Avertisov, V.A. Baulin, W. Lauga, W.B. Wood, W.B. Wood, W.B. Wood, W.R. DiLuzio, X.-Q. Shi, Y. Nakadera, Y. Shibazaki, Y. Wu, Y.B. Malashichev   +100 more
core   +1 more source

Contribution of Gli1+ Adventitial Stem Cells to Smooth Muscle Cells in Atherosclerosis and Vascular Injury

Advanced Science, EarlyView.
Gli1+ adventitial stem cells (ASCs) have been thought to generate smooth muscle cells (SMCs) in atherosclerosis. Using a dual‐recombinase lineage tracing to exclude ectopic labeling, Wang et al. found that Gli1+ ASCs do not contribute to SMCs in atherosclerotic plaques.
Haixiao Wang, Xiuzhen Huang, Jialing Mou, Enci Wang, Yan Li, Wenjuan Pu, Yao Xie, Xiaoling Guo, Lixin Wang, Maoping Chu, Bin Zhou, Chao Niu   +11 more
wiley   +1 more source

One must reconstitute the functions of interest from purified proteins

Frontiers in Physiology
I am often asked by students and younger colleagues and now by the editors of this issue to tell the history of the development of the in vitro motility assay and the dual-beam single-molecule laser trap assay for myosin-driven actin filament movement ...
James A. Spudich
doaj   +1 more source

On Myosin II dynamics in the presence of external loads

, 2005
We address the controversial hot question concerning the validity of the loose coupling versus the lever-arm theories in the actomyosin dynamics by re-interpreting and extending the phenomenological washboard potential model proposed by some of us in a ...
Buonocore, A., Caputo, L., Ishii, Y., Pirozzi, E., Ricciardi, L. M., Yanagida, T.   +5 more
core   +2 more sources