Results 121 to 130 of about 380,707 (403)
Elastic Energy Storage in Biological Materials: Internal Stresses and Their Functionality
Advanced Materials, EarlyView.Harnessing and storing internally generated elastic energy is a clever strategy by biological materials to perform functions like shape transformation, movement, and predation. This review explores how biological systems manipulate mechanisms like atomic or protein integration into minerals, protein conformational shifts, phase transitions, and osmotic
Shahrouz Amini +3 more
wiley +1 more source
Nature Cell Biology, 2015 Primitive streak formation in the chick embryo involves large-scale highly coordinated flows of more than 100,000 cells in the epiblast. These large-scale tissue flows and deformations can be correlated with specific anisotropic cell behaviours in the ...
Emil Rozbicki +8 more
semanticscholar +1 more source
On Myosin II dynamics in the presence of external loads
, 2005 We address the controversial hot question concerning the validity of the loose coupling versus the lever-arm theories in the actomyosin dynamics by re-interpreting and extending the phenomenological washboard potential model proposed by some of us in a ...
Buonocore, A. +5 more
core +2 more sources
Tailored Xenogeneic‐Free Polymer Surface Promotes Dynamic Migration of Intestinal Stem Cells
Advanced Materials, EarlyView.This study introduces a PoLymer‐coated Ultra‐stable Surface (PLUS), a nitrogen plasma‐treated poly(ethyleneglycoldimethacrylate), as a stable xenogeneic‐free platform for intestinal stem cell culture. PLUS enhances cell attachment, supports actin‐driven migration, and retains functionality after 3 years of storage. Promoting cytoskeletal reorganization,
Seonghyeon Park +13 more
wiley +1 more source
Myosin-5 varies its steps along the irregular F-actin track [PDF]
, 2023 Adam Fineberg +12 more
openalex +1 more source
Macrophages Mediate Mesoscale Brain Mechanical Homeostasis
Advanced Materials, EarlyView.We investigated the role of infiltrating immune cells in sculpting the developing brain. Using Brillouin microscopy and active microrheology, we found microglia actively maintain tissue viscoelasticity. Moreover, colony stimulating factor one receptor (CSF1R)‐driven stromal remodeling alters brain mechanics in vivo. These findings link immune activity,
Woong Young So +11 more
wiley +1 more source
Czech Journal of Food Sciences, 2009 Phenolic compounds were extracted from bearberry (Arctostaphylos uva-ursi L. Sprengel) leaves into 95% (v/v) ethanol. The tannin constituents were separated from the crude extract using Sephadex LH-20 column chromatography with 95% (v/v) ethanol and 50% (
Ryszard Amarowicz +2 more
doaj +1 more source
Integrin α8‐Mediated Pericyte Morphogenesis Controls Blood‐Brain Barrier Integrity
Advanced Science, EarlyView.This study highlights that ITGA8 impacts pericyte morphology and function, both crucial for BBB integrity, via RhoA/ROCK signaling, thus influencing TGF‐β1 activation through cytoskeletal tension and ECM interactions. Notably, in post‐ischemic recovery models, ITGA8 deficiency exacerbates vascular dysfunction by impairing pericyte‐mediated BBB ...
Chang‐Xiong Gong +16 more
wiley +1 more source
Non-muscle myosin IIB is critical for nuclear translocation during 3D invasion
Journal of Cell Biology, 2015 Non-muscle myosin IIB plays a major role in applying force on the nucleus to facilitate nuclear translocation through tight spaces during 3D invasive migration, while non-muscle myosin IIA is critical for generating force during active protrusion.
Dustin G Thomas +9 more
semanticscholar +1 more source
Mechanobiological Dynamics‐Inspired Mechanomodulatory Biomaterials
Advanced Science, EarlyView.Recent advances in biomaterial‐mediated mechanomodulation of stem cell fate, encompassing 2, 3, and 4D systems and their synergy with artificial intelligence is overviewed. By integrating knowledge from diverse fields, this review ultimately aims to inspire the design of smarter biomaterial systems that can accelerate the clinical translation of ...
Letao Yang +6 more
wiley +1 more source