Results 151 to 160 of about 20,285 (238)

Mitochondrial dysfunction: Related diseases, influencing factors, and detection

Interdisciplinary Medicine, EarlyView.
Mitochondrial dysfunction is implicated in the pathogenesis of numerous diseases, including neurological disorders, cancers, and cardiovascular conditions, through mechanisms such as mitochondrial DNA mutations, dysregulation of mitochondrial network dynamics, and impaired mitophagy.
Zhaojin Li, Shiyu Li, Wanying Chen, Ziyu Zhang, Chun Pan, Peng Lei, Cheng Cheng, Junyou Zhu, Hanxiao Sun, Zhenning Dai   +9 more
wiley   +1 more source

An allosteric inhibitor of RhoGAP class-IX myosins suppresses the metastatic features of cancer cells. [PDF]

Nat Commun
Kyriazi D, Voth L, Bader A, Ewert W, Gerlach J, Elfrink K, Franz P, Tsap MI, Schirmer B, Damiano-Guercio J, Hartmann FK, Plenge M, Salari A, Schöttelndreier D, Strienke K, Bresch N, Salinas C, Gutzeit HO, Schaumann N, Hussein K, Bähre H, Brüsch I, Claus P, Neumann D, Taft MH, Shcherbata HR, Ngezahayo A, Bähler M, Amiri M, Knölker HJ, Preller M, Tsiavaliaris G.   +31 more
europepmc   +1 more source

Atrial cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 727-729, April 2025.
Wojciech Kosmala, Monika Przewłocka‐Kosmala   +1 more
wiley   +1 more source

A Simple and Fast Optical Clearing Method for Whole‐Mount Fluorescence In Situ Hybridization (FISH) Imaging

Journal of Biophotonics, EarlyView.
In this article, we present 3D‐LIMPID‐FISH: a simple and fast optical clearing method for acquiring 3D images of fluorescence in situ hybridization probes. Figures and movies are provided to showcase the technology, and a detailed protocol is provided to replicate the result.
Junwoo Suh, Yehe Liu, Jordan Smith, Michiko Watanabe, Andrew M. Rollins, Michael W. Jenkins   +5 more
wiley   +1 more source

Pathophysiology of human hearing loss associated with variants in myosins. [PDF]

Front Physiol
Miyoshi T, Belyantseva IA, Sajeevadathan M, Friedman TB.   +3 more
europepmc   +1 more source

Influence of native thin filament type on the regulation of atrial and ventricular myosin motor activity. [PDF]

J Biol Chem
Spahiu E, Uta P, Kraft T, Nayak A, Amrute-Nayak M.   +4 more
europepmc   +1 more source

Importance of proteins and mitochondrial changes as freshness indicators in fish muscle post‐mortem

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Evaluating protein and mitochondrial alterations post‐mortem can contribute to determining correlations between fish‐processing parameters and ultimate fish muscle quality. The myofibrillar protein alteration during rigor mortis directly affects the texture of fish muscle.
Nima Hematyar, Tomas Policar, Turid Rustad   +2 more
wiley   +1 more source

Cellular Partners of Tobamoviral Movement Proteins. [PDF]

Int J Mol Sci
Ershova NM, Kamarova KA, Sheshukova EV, Komarova TV.   +3 more
europepmc   +1 more source

Kinesin‐Driven De‐Mixing of Cytoskeleton Composites Drives Emergent Mechanical Properties

Macromolecular Rapid Communications, EarlyView.
Optical tweezers microrheology and fluorescence microscopy is coupled with simulations and mathematical modeling to discover that active cytoskeleton composites exhibit a rich ensemble of emergent mechanical response characteristics, from yielding to stiffening, governed by kinesin‐driven restructuring from well‐mixed interpenetrating double‐networks ...
Janet Sheung, Christopher Gunter, Katarina Matic, Mehrzad Sasanpour, Jennifer L. Ross, Parag Katira, Megan T. Valentine, Rae M. Robertson‐Anderson   +7 more
wiley   +1 more source

Are the class 18 myosins Myo18A and Myo18B specialist sarcomeric proteins? [PDF]

Front Physiol
Horsthemke M, Arnaud CA, Hanley PJ.
europepmc   +1 more source