Results 151 to 160 of about 40,761 (237)

Pharmacological Inhibition of β Myosin II Disrupts Sarcomere Assembly in Human iPSC‐Derived Cardiac Myocytes

Cytoskeleton, EarlyView.
ABSTRACT Sarcomeres are the fundamental contractile units of striated muscle. The functional roles of the cardiac‐specific myosin heavy chains, MYH6 (α myosin II) and MYH7 (β myosin II) during sarcomere assembly remain controversial. To address this, we utilized a selective MYH7 inhibitor, mavacamten, in combination with siRNA‐mediated knockdown of ...
James B. Hayes, Dylan T. Burnette
wiley   +1 more source

The filopodial myosin DdMyo7 is a slow, calcium-regulated motor. [PDF]

J Biol Chem
Eddington C, Titus MA.
europepmc   +1 more source

Myocardial Infarct Size by Serum Troponin T and Myosin Light Chain 1 Concentration.

, 1995
Takashi Omura, Masakazu Teragaki, Masahiko Takagi, Tomoko Tani, Yukio Nishida, Hiroyuki Yamagishi, Shiro Yanagi, Toshio Nishikimi, Minoru Yoshiyama, Iku Toda, Kaname Akioka, Kazuhide Takeuchi, Tadanao Takeda   +12 more
openalex   +2 more sources

Disruption of Myosin 1e Promotes Podocyte Injury [PDF]

, 2008
Mira Krendel, Sangwon V. Kim, Tim Willinger, Tong Wang, Michael Kashgarian, Richard A. Flavell, Mark S. Mooseker   +6 more
openalex   +1 more source

Skeletal muscle myosin heavy chain expression and 3D capillary network changes in streptozotocin-induced diabetic female mice

, 2023
Nejc Umek, Luka Pušnik, Chiedozie Kenneth Ugwoke, Žiga Šink, Simon Horvat, Jiřı́ Janáček, Erika Cvetko   +6 more
openalex   +2 more sources

The PP2A‐B56 Binding Site LxxIxE Contributes to Asp‐Mediated Spindle Pole Stability

Cytoskeleton, EarlyView.
ABSTRACT The organization of microtubules into a mitotic spindle is critical for animal cell proliferation and involves the cooperation of hundreds of proteins whose molecular roles and regulation are not fully understood. The protein product of the Drosophila gene abnormal spindle, Asp, is a microtubule‐associated protein required for correct mitotic ...
Margaux Quiniou, Maria C. Burns, Aynsley McDermott, Karolina Jaworek, Stacey J. Scott, James G. Wakefield, Lori Borgal   +6 more
wiley   +1 more source

3D-environment and muscle contraction regulate the heterogeneity of myonuclei. [PDF]

Skelet Muscle
Nicolas R, Bonnin MA, Blavet C, de Lima JE, Legallais C, Duprez D.   +5 more
europepmc   +1 more source

Brownian Search-and-Catch Mechanism for Myosin-VI Steps

, 2010
Mitsuhiro Iwaki
openalex   +2 more sources

Double heterozygosity for mutations in the β-myosin heavy chain and in the cardiac myosin binding protein C genes in a family with hypertrophic cardiomyopathy [PDF]

, 1999
Pascale Richard, Richard Isnard, Lucie Carrier, Olivier Dubourg, Yves Donatien, Bénédicte Mathieu, Gisèle Bonne, Françoise Gary, Philippe Charron, Albert Hagège, Michel Komajda, Ketty Schwartz, Bernard Hainque   +12 more
openalex   +1 more source

Conserved Phosphorylation of the Myosin1e TH1 Domain Impacts Membrane Association and Function in Yeast and Worms

Cytoskeleton, EarlyView.
ABSTRACT Cells have an intrinsic ability to rapidly respond to environmental change to regulate cell cycle progression and membrane organisation, thereby affecting cell growth and division. The actin cytoskeleton is a highly dynamic complex of proteins that can rapidly reorganise to change the growth pattern of a cell.
Holly R. Brooker, Karen Baker, Marina Ezcurra, Philippe P. Laissue, Lin Wang, Michael A. Geeves, Jennifer M. Tullet, Daniel P. Mulvihill   +7 more
wiley   +1 more source