Results 161 to 170 of about 12,413 (263)
Impact of mechanical unloading on the irisin precursor, FNDC5, in skeletal muscle of sheep as a large animal experimental model. [PDF]
Suriano C +10 more
europepmc +1 more source
OXCT1‐driven succinylation of PSMG3 stabilizes the proteasome to facilitate picornavirus replication
Upon entering the pig, foot‐and‐mouth disease virus (FMDV) regulates host glycolysis and the citrate cycle by modulating the expression of metabolic enzymes, resulting in changes in post‐translational modifications (PTMs) including succinylation, lactylation, crotonylation, acetylation, and phosphorylation.
Huisheng Liu +9 more
wiley +1 more source
Pulmonary parenchyma becomes a self-organized dissipative structure in lung cancers and pulmonary inflammatory diseases. [PDF]
Lecarpentier Y +7 more
europepmc +1 more source
ABSTRACT The global incidence of intestinal diseases—including food allergy, inflammatory bowel disease (IBD), and colorectal cancer (CRC)—continues to escalate in parallel with the expansion of the “Western diet,” within which the high‐sugar diet (HSD) has emerged as a pivotal yet under‐recognized dietary driver.
Yuchen Wang +9 more
wiley +1 more source
Exploring phosphoregulation of MYO3A using quantitative fluorescence image analysis in COS7 cells. [PDF]
Phan VMN, Quintero-Carmona OA.
europepmc +1 more source
Mechanical memory in aging: From adaptive sensing to pathological entrenchment
Mechanical memory in aging operates through four temporal tiers, from cytoskeletal remodeling to metabolic reprogramming. Aging disrupts this cascade through three distinct decoupling patterns: sensor degradation, conduction blockade, and execution failure, leading to irreversible pathological entrenchment across multiple organ systems.
Mingyang Huang +7 more
wiley +1 more source
Contractility Drives Cardiomyocyte Maturation and the Response to Nanopatterns. [PDF]
Sherer LA +12 more
europepmc +1 more source
ESC Heart Failure, Volume 12, Issue 2, Page 727-729, April 2025.
Wojciech Kosmala +1 more
wiley +1 more source
Abstract Objectives Monogenic causes of congenital diarrheas and enteropathies (CoDE) and very early onset inflammatory bowel disease (VEOIBD) are mostly recessive and therefore more prevalent in populations with increased consanguinity rates. To assess the genetic basis of these disorders in a likely high‐prevalence population, we established a multi ...
Lily Gillette +21 more
wiley +1 more source

