Results 191 to 200 of about 20,285 (238)

Active transport enables protein condensation in cells. [PDF]

Sci Adv
Chauhan G, Wilkinson EG, Yuan Y, Cohen SR, Onishi M, Pappu RV, Strader LC.   +6 more
europepmc   +1 more source

The SUV39 Family of H3K9 Methyltransferases in Skeletal Muscle Stem Cells

FASEB BioAdvances, EarlyView.
The SUV39 family members are well known for methylating the Lysine 9 of the histone H3 (H3K9) in order to compact the chromatin and contributing to gene repression. We describe their active role in proliferating and differentiating muscle stem cells, how they prevent from inflammation and fibrosis during muscle regeneration and the future avenues ...
Pauline Garcia, Slimane Ait‐Si‐Ali, Fabien Le Grand   +2 more
wiley   +1 more source

Homologous mutations in human β, embryonic, and perinatal muscle myosins have divergent effects on molecular power generation. [PDF]

Proc Natl Acad Sci U S A
Liu C, Karabina A, Meller A, Bhattacharjee A, Agostino CJ, Bowman GR, Ruppel KM, Spudich JA, Leinwand LA.   +8 more
europepmc   +1 more source

Impact of Acute Endurance Exercise on Alternative Splicing in Skeletal Muscle

FASEB BioAdvances, EarlyView.
Current model on the effects of acute endurance exercise on the AS regulatory mechanism with key trans‐factors/RBPs (e.g., hnRNP‐A1, ‐A3, and TIA1). ABSTRACT Alternative splicing (AS) is a highly conserved posttranscriptional mechanism, generating mRNA variants to diversify the proteome.
Alexander Ahn, Jeongjin J. Kim, Aaron L. Slusher, Jeffrey Y. Ying, Eric Y. Zhang, Andrew T. Ludlow   +5 more
wiley   +1 more source

ATP-induced reconfiguration of the micro-viscoelasticity of cardiac and skeletal myosin solutions. [PDF]

Appl Phys Lett
Domínguez-García P, Pinto JR, Akrap A, Jeney S.   +3 more
europepmc   +1 more source

detectEVE: Fast, Sensitive and Precise Detection of Endogenous Viral Elements in Genomic Data

Molecular Ecology Resources, Volume 25, Issue 4, May 2025.
ABSTRACT Endogenous viral elements (EVEs) are fragments of viral genomic material embedded within the host genome. Retroviruses contribute to the majority of EVEs because of their genomic integration during their life cycle; however, the latter can also arise from non‐retroviral RNA or DNA viruses, then collectively known as non‐retroviral (nr) EVEs ...
Nadja Brait, Thomas Hackl, Sebastian Lequime   +2 more
wiley   +1 more source

A therapeutic leap: how myosin inhibitors moved from cardiac interventions to skeletal muscle myopathy solutions. [PDF]

J Clin Invest
Bogomolovas J, Chen J.
europepmc   +1 more source

Proteome profiling of cerebrospinal fluid using machine learning shows a unique protein signature associated with APOE4 genotype

Aging Cell, Volume 24, Issue 4, April 2025.
We sought to identify the cerebrospinal fluid protein (CSF) changes that are associated with the APOE4 genetic variant to better understand the vulnerability of APOE4 carriers to progress to Alzheimer's disease (AD) with age. To do this, we used machine learning and enrichment analyses to analyze 6082 proteins in the CSF of cognitively normal, mild ...
Artur Shvetcov, Shannon Thomson, Ann‐Na Cho, Heather M. Wilkins, Joanne H. Reed, Russell H. Swerdlow, David A. Brown, the Alzheimer's Disease Neuroimaging Initiative, Caitlin A. Finney   +8 more
wiley   +1 more source

Myosin-I's motor and actin assembly activation activities are modular and separable in budding yeast clathrin-mediated endocytosis. [PDF]

MicroPubl Biol
Hill JM, Pedersen RT, Drubin DG.
europepmc   +1 more source

From Clinical to Benchside: Lacticaseibacillus and Faecalibacterium Are Positively Associated With Muscle Health and Alleviate Age‐Related Muscle Disorder

Aging Cell, Volume 24, Issue 5, May 2025.
Old people with or without sarcopenia exhibited different gut microbiota and metabolite compositions. Mice receiving microbes from people with sarcopenia displayed lower muscle mass and strength compared with those receiving microbes from non‐sarcopenic donors.
Chaoran Liu, Pui Yan Wong, Nilakshi Barua, Baoqi Li, Hei Yuet Wong, Ning Zhang, Simon Kwoon Ho Chow, Sunny Hei Wong, Jun Yu, Margaret Ip, Wing Hoi Cheung, Gustavo Duque, Christoph Brochhausen, Joseph Jao Yiu Sung, Ronald Man Yeung Wong   +14 more
wiley   +1 more source