Results 71 to 80 of about 50,269 (229)

Enhanced reaction kinetics in biological cells

, 2008
The cell cytoskeleton is a striking example of "active" medium driven out-of-equilibrium by ATP hydrolysis. Such activity has been shown recently to have a spectacular impact on the mechanical and rheological properties of the cellular medium, as well as
A Ajdari, B Alberts, C Storm, C. Loverdo, D Holcman, D Mizuno, F Nedelec, FJ Nedelec, G Kolesov, H Salman, I Eliazar, J Howard, K Kruse, L Le Goff, M Coppey, M Slutsky, M. Moreau, MA Lomholt, MF Shlesinger, MF Shlesinger, MP Sheetz, O Berg, O Bénichou, O Bénichou, O Bénichou, O Thoumine, O. Bénichou, P Dalhaimer, R Voituriez, R Voituriez, R. Voituriez, S Condamin, S Huet, S Redner   +33 more
core   +1 more source

Prime movers : mechanochemistry of mitotic kinesins [PDF]

, 2014
Mitotic spindles are self-organizing protein machines that harness teams of multiple force generators to drive chromosome segregation. Kinesins are key members of these force-generating teams.
A Blangy, A Groen, A Hutterer, A Jannasch, A Karabay, A Toso, A Yildiz, AA Levesque, AB Asenjo, AC Groen, AE Butterfield, AF Huxley, AF Straight, AJ Roberts, AM Mulder, AM Saunders, Andrew McAinsh, AS Kashina, AS Khalil, B Gigant, B Owens, B Wickstead, BH Kwok, BH Kwok, BJ Grant, BT Schaar, C Antonio, C Hentrich, C Peters, C Thiede, C Wandke, CA Watts, CC Leduc, CE Walczak, CJ Lawrence, CK Hu, CL Parke, CL Rieder, CL Rieder, CM Whitehead, CTC Friel, CV Sindelar, CV Sindelar, D Vanneste, D Vanneste, DA Compton, E Doménech, E Karsenti, E Vladimirou, EG Sturgill, ER Hildebrandt, FJ Kull, FJ Kull, G Fink, GC Rogers, GJ Brouhard, GJ Gorbsky, GJPL Kops, H Aizawa, H Boleti, H Drechsler, H Funabiki, H Yardimci, HS Sardar, HS Sardar, HYK Kaan, I Brust-Mascher, I Brust-Mascher, I Minoura, IM Crevel, IM-TC Crevel, J Espeut, J Helenius, J Roostalu, J Roostalu, J Rosenblatt, J Stumpff, J Stumpff, J Stumpff, J Yajima, JC Cochran, JC Gatlin, JC Waters, JM Scholey, JPI Welburn, JR Aist, JR Cooper, JR McIntosh, JRJ Stout, JS Allingham, JS Weinger, K Hahlen, K Jaqaman, K Kaseda, K Kaseda, K Samejima, KE Gascoigne, KJ Verhey, KS Burbank, KW Wood, KW Wood, KY Lee, L Wordeman, LC Kapitein, LC Kapitein, LN Weaver, LR Sproul, M Braun, M Braun, M Glotzer, M Joshi, M Kikkawa, M Klejnot, M Mishima, M Nishiyama, M Wagenbach, MA Hoyt, MA Seeger, MC Alonso, ME Douglas, ME Tanenbaum, ME Tanenbaum, ME Tanenbaum, MI Mayr, MJ Korneev, ML Gupta, MT Valentine, MT Valentine, N Gudimchuk, N Hirokawa, N Hirokawa, N Joseph, NF Endres, NJ Carter, NJ Ganem, OO Rath, P Bieling, Q Chang, R Nitta, R Nunes Bastos, R Uehara, RB Case, RD Vale, Robert A. Cross, S Acar, S Cai, S Cane, S Debonis, S Diez, S Dumont, S Highsmith, S Inoué, S Oh, S Rice, S Rice, S Shastry, SF Bakhoum, SS Rosenfeld, SS Rosenfeld, SW Grill, T Krzysiak, T Maney, T Surrey, TJ Mitchison, TJ Mitchison, TM Kapoor, TT Ogawa, V Fridman, V Magidson, V Mountain, V Varga, VV Bormuth, W Saunders, WW Wang, X Su, X Su, Y Du, Y Kim, Y Kurasawa, Y Oguchi, Y Zhai, YF Dufrene, YM Lee, YY Okada, Z Yang   +184 more
core   +1 more source

SILAC-based proteomic quantification of chemoattractant-induced cytoskeleton dynamics on a second to minute timescale [PDF]

, 2014
Cytoskeletal dynamics during cell behaviours ranging from endocytosis and exocytosis to cell division and movement is controlled by a complex network of signalling pathways, the full details of which are as yet unresolved.
A Bagorda, A Kortholt, A Kortholt, A Para, A Shevchenko, AJ Saldanha, AT Sasaki, C Orelio, CL Chen, CL Manahan, DM Veltman, DM Veltman, DM Veltman, EC Rericha, EL de Hostos, F Friedberg, F Vazquez, G Vlahou, H Cai, H Kae, HR Bourne, I Marin, J Condeelis, J Cox, J Faix, J Riedl, J Schindelin, J Yan, JF Cote, JF Cote, JW Han, JY Kim, KF Swaney, L Bosgraaf, L Bosgraaf, L Bosgraaf, L Chen, M Affolter, M Brenner, M de la Roche, M Patel, MJ de Hoon, MK Vartiainen, MR Lee, MS Boguski, N Ibarra, N Meller, OD Weiner, R Insall, RH Insall, RJ Eddy, S Hanna, S Levi, SE Ong, SJ Allen, SL Blagg, TJ Jeon, WN van Egmond, X Xu, Y Yang, YC Wu   +60 more
core   +3 more sources

Evolution: functional evolution of nuclear structure. [PDF]

, 2011
The evolution of the nucleus, the defining feature of eukaryotic cells, was long shrouded in speculation and mystery. There is now strong evidence that nuclear pore complexes (NPCs) and nuclear membranes coevolved with the endomembrane system, and that ...
Dawson, Scott C, Wilson, Katherine L
core  

Structures of smooth muscle myosin and heavy meromyosin in the folded, shutdown state [PDF]

, 2007
Remodelling of the contractile apparatus within smooth muscle cells is an essential process that allows effective contractile activity over a wide range of cell lengths.
Ankrett, Burgess, Burgess, Burgess, Craig, Craig, Cremo, Cross, Dominguez, Elliott, Elliott, Frank, Fraser, Frederiksen, Gourinath, Houdusse, Hvidt, Ikebe, Joseph M. Chalovich, Knight, Knight, Lauzon, Liu, Matt L. Walker, Mazhari, Offer, Offer, Offer, Olney, Onishi, Onishi, Penczek, Persechini, Peter J. Knight, Quinlan, Rayment, Rhoda J. Hawkins, Rimm, Salzameda, Sellers, Seow, Sheng, Shuizi Yu, Sobieszek, Stafford, Stan A. Burgess, Suzuki, Tama, Thirumurugan, Tonino, Trybus, Trybus, Trybus, Trybus, Wahlstrom, Walker, Wendt, Wendt, Woodhead, Wu, Yanagisawa   +60 more
core   +1 more source

Coordinated force generation of skeletal myosins in myofilaments through motor coupling

Nature Communications, 2017
Skeletal muscle myosin forms large ensembles to generate force against high loads. Using optical tweezers and simulation Kayaet al. provide experimental evidence for cooperative force generation, and describe how the molecular properties of skeletal ...
Motoshi Kaya, Yoshiaki Tani, Takumi Washio, Toshiaki Hisada, Hideo Higuchi   +4 more
doaj   +1 more source

Association of six YFP-myosin XI-tail fusions with mobile plant cell organelles

BMC Plant Biology, 2007
Background Myosins are molecular motors that carry cargo on actin filaments in eukaryotic cells. Seventeen myosin genes have been identified in the nuclear genome of Arabidopsis.
Hanson Maureen R, Reisen Daniel
doaj   +1 more source

Collective dynamics of actomyosin cortex endow cells with intrinsic mechanosensing properties

, 2015
Living cells adapt and respond actively to the mechanical properties of their environment. In addition to biochemical mechanotransduction, evidence exists for a myosin-dependent, purely mechanical sensitivity to the stiffness of the surroundings at the ...
Asnacios, Atef, Bufi, Nathalie, Durand-Smet, Pauline, Fouchard, Jonathan, Mitrossilis, Démosthène, Étienne, Jocelyn   +5 more
core   +3 more sources

Rapid chromosome territory relocation by nuclear motor activity in response to serum removal in primary human fibroblasts [PDF]

, 2010
This article has been made available through the Brunel Open Access Publishing Fund.Background: Radial chromosome positioning in interphase nuclei is nonrandom and can alter according to developmental, differentiation, proliferation, or disease status.
Amira, M, Bridger, JM, Harvey, AJ, Mehta, IS   +3 more
core   +2 more sources

Three Hierarchies in Skeletal Muscle Fibre Classification Allotype, Isotype and Phenotype [PDF]

Immunocytochemical analyses using specific anti-myosin antibodies of mammalian muscle fibers during regeneration, development, and after denervation have revealed two distinct myogenic components determining fiber phenotype.
Hoh, Joseph F. Y., Hugh, Gregory, Hughes, Suzanne, Pozgaj, Irene   +3 more
core   +1 more source