Results 111 to 120 of about 15,479 (238)
Ubiquitin Proteasom System und Myopathien [PDF]
Objective: In idiopathic inflammatory myopathies (IIM) infiltration of immune cells into muscle and upregulation of MHC-I expression implies increased antigen presentation and involvement of the proteasome system.
Ghannam, Khetam
core +1 more source
Objective This systematic review documents the current status of extracorporeal membrane oxygenation (ECMO) use in patients with complications of rheumatologic diseases. Methods Following Preferred Reporting Items for Systematic Reviews and Meta Analyses 2020 guidelines, we conducted a systematic review of studies published from January 2019 to ...
Kari L. Falaas +3 more
wiley +1 more source
Shoulder Rotation Test: A New Test for Discriminating Between Functional and Structural Weakness
We introduce the shoulder rotation test, a simple bedside test combining the MRC scoring of shoulder internal rotation (IR) and external rotation (ER), for discriminating between functional weakness (FW) and structural weakness (SW) of the upper limbs.
Takamichi Kanbayashi, Masahiro Sonoo
wiley +1 more source
ABSTRACT Introduction and Methods Cancer therapy–related cardiac dysfunction (CTRCD) is a well established and potentially life‐threatening complication of contemporary oncologic treatment. Although comprehensive cardio‐oncology guidelines have been developed, their integration into routine hematology and oncology practice remains inconsistent.
Abdelrahman Ali +22 more
wiley +1 more source
ABSTRACT Introduction Immune checkpoint inhibitors (ICIs) are an important treatment option in bladder cancer, but clinical trials have demonstrated that they are associated with immune‐related adverse events (irAEs), such as rash, hypothyroidism, hyperthyroidism, and others. This study aimed to evaluate real‐world evidence of these irAEs using the FDA
Pooja Gokhale, Lorenzo Villa Zapata
wiley +1 more source
Current essentials in inflammatory myopathies [PDF]
Inflammatory myopathies are a heterogeneous group of acquired systemic diseases, which include dermatomyositis (DM), polymyositis (PM), necrotising myopathy (NM) and inclusion body myositis (IBM).
Maren Breithaupt, Jens Schmidt
doaj
Clinical Safety of Extended Interval Dosing of Nivolumab in Patients with Melanoma
Extended interval dosing regimens of immune checkpoint inhibitors have been implemented widely. However, their approval was mainly based on pharmacokinetic modeling and simulations. Consequently, comparative safety data of extended interval dosing regimens in a real‐world setting are limited.
Ruben Malmberg +10 more
wiley +1 more source
ABSTRACT Hypercontractile esophagus is a motility disorder characterized by excessive contractions in the esophageal body. Certain cases of hypercontractile esophagus exhibit eosinophilic infiltration in the muscle layer; however, its clinical significance is unclear.
Tetsuya Tatsuta +9 more
wiley +1 more source
Zusammenfassung: Zu den idiopathischen inflammatorischen Myositiden zählen die Dermatomyositis (DM), Polymyositis (PM), die Einschlusskörperchenmyositis ("inclusion body myositis", IBM) und die nekrotisierende autoimmune Myopathie (NAM).
Keck, A.D., Walker, U.A.
core

