Results 121 to 130 of about 15,479 (238)

Risk Factors for Recurrence of the Anti‐Synthetase Syndrome Related Interstitial Lung Disease

open access: yesImmunity, Inflammation and Disease, Volume 14, Issue 4, April 2026.
ABSTRACT Purpose This current study aimed to detect the risk factors for recurrence of the anti‐synthetase syndrome related interstitial lung disease (ASSD‐ILD). Methods Patients who were diagnosed with ASSD‐ILD and achieved the improving standards after treatment at a single clinical center from January 1, 2017 to January 1, 2022 were retrospectively ...
Zhen‐Yu Ren   +4 more
wiley   +1 more source

Post‐COVID‐19 Area Postrema Syndrome With SARS‐CoV‐2 in CSF: A Dual‐Case Report and Review of the Literature

open access: yesImmunity, Inflammation and Disease, Volume 14, Issue 4, April 2026.
This dual‐case report describes two patients with post‐COVID‐19 area postrema syndrome whose outcomes were dictated by their AQP4‐IgG serostatus, despite both having SARS‐CoV‐2 detected in their CSF. The stark contrast between the seronegative patient's recovery and the seropositive patient's fatal relapse highlights antibody testing as an urgent and ...
Wan Zhu   +4 more
wiley   +1 more source

Dysphagia in Patients with Sporadic Inclusion Body Myositis: Management Challenges

open access: yesInternational Journal of General Medicine, 2019
Nika Mohannak,1 Gemma Pattison,2 Kathryn Hird,1 Merrilee Needham1,3,4 1School of Medicine, The University of Notre Dame, Fremantle, Western Australia, Australia; 2Department of Speech Pathology, Royal Perth Hospital, Perth, Western Australia, Australia ...
Mohannak N   +3 more
doaj  

Clinicopathologic Characterization of Muscle Biopsy Findings in Overlap Myositis: A Single Tertiary Care Center Experience

open access: yesImmunity, Inflammation and Disease, Volume 14, Issue 4, April 2026.
ABSTRACT Objective This study aims to describe the muscle biopsy features of overlap myositis (OM) and compare them with other inflammatory myopathies. We analyzed clinical, serological findings, and histopathological patterns in muscle biopsies to understand the features of OM.
Sidra Fatima   +5 more
wiley   +1 more source

Steroid‐Refractory Chronic Graft‐Versus‐Host Disease–Associated Isolated Myositis Successfully Treated With Ruxolitinib: A Case Report

open access: yeseJHaem, Volume 7, Issue 2, April 2026.
ABSTRACT Chronic graft‐versus‐host disease (cGVHD) is a major late complication following allogeneic hematopoietic stem cell transplantation (HSCT), in which musculoskeletal involvement, particularly isolated myositis, is extremely rare. We report a case of cGVHD‐associated myositis in a man in his 40s who underwent allogeneic bone marrow ...
Tomoko Kumamoto   +9 more
wiley   +1 more source

Application and Challenges of Chimeric Antigen Receptor T Cell Therapy in Systemic Rheumatic Diseases and Autoimmune Disorders

open access: yesMedComm, Volume 7, Issue 4, April 2026.
CAR‐T cell therapy in systemic rheumatic diseases and autoimmune disorders. (This figure was created using BioRender.com.) ABSTRACT Chimeric antigen receptor T (CAR‐T) cell therapy, originally developed for hematologic malignancies, has emerged as a transformative candidate for systemic rheumatic diseases and autoimmune disorders (AIDs).
Zhidan Fan, Li Zhang, Haiguo Yu
wiley   +1 more source

Systematic Proteomic Characterization of EV‐A71‐Infected Mice Identifies Dynamic Molecular Changes and Therapeutic Targets

open access: yesMedComm, Volume 7, Issue 4, April 2026.
Time‐resolved multi‐omics of EV‐A71‐infected BALB/c mice uncovered dynamic host responses, revealing rapid neutrophil extracellular traps (NETs) activation as a key event. Screened drugs (kinase inhibitors) suppressed viral replication in vitro and in vivo, suggesting the promise of targeting host phosphorylation networks as a viable antiviral strategy.
Wanjun Peng   +11 more
wiley   +1 more source

Osmolytes as mediators of the muscle tissue’s responses to inflammation : emerging regulators of myositis with therapeutic potential [PDF]

open access: yes, 2017
Chronic inflammation of skeletal muscle tissues termed myositis is associated with inherited muscular dystrophy and with acquired inflammatory myopathy.
De Paepe, Boel
core   +1 more source

Impact of Pharmacokinetic Gene Polymorphisms on Statin‐Induced Myotoxicity in Thai Patients Treated With Simvastatin

open access: yesClinical and Translational Science, Volume 19, Issue 4, April 2026.
ABSTRACT Statin‐induced myotoxicity (SIM) is a common adverse effect of simvastatin therapy, which can negatively impact patient adherence and treatment outcomes. This study aims to investigate the impacts of pharmacokinetic (PK) gene polymorphisms on SIM in Thai population treated with simvastatin.
Sayanit Tipnoppanon   +6 more
wiley   +1 more source

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