Results 131 to 140 of about 15,479 (238)

Rituximab in the treatment of inflammatory myopathies: a review [PDF]

, 2017
Several uncontrolled studies have encouraged the use of rituximab (RTX) in patients with myositis. Unfortunately, the first placebo-phase trial to assess the efficacy of RTX in refractory myositis did not show a significant difference between the two ...
Fasano, S, Gordon, P, Hajji, R, Isenberg, DA, Loyo, E   +4 more
core  

Epidemiology and Genetics of Rheumatic Diseases Suggest a Constant Rate of DNA Damage as Underlying Cause

Immunology, Volume 177, Issue 4, Page 736-748, April 2026.
A constant rate of DNA damage that is not perfectly repaired will cause a constant rate of DNA mutations. The chance of mutation will increase if DNA is prone to damage, such as occurs in somatic hypermutation (SHM) hotspots and GC‐rich DNA. Thus, if one mutation‐prone DNA site drives disease, the age of onset of disease and degree of penetrance should
Piet C. de Groen
wiley   +1 more source

Sharing Is Caring?—Pathogens and Pathogen‐Specific Antibodies in Arctic Endemic Seal Species and the Newly Sympatric Harbor Seals in Kongsfjorden, Svalbard

Marine Mammal Science, Volume 42, Issue 2, April 2026.
ABSTRACT Climate change associated transformations of Arctic marine ecosystems are having detrimental impacts on Arctic endemic marine mammals. However, warming conditions are providing new habitats for temperate marine mammals, some of which are expanding into Arctic regions, posing a threat of novel pathogen introduction and disease transmission.
Luca A. Schick, Kit M. Kovacs, Christian Lydersen, Simon Rohner, Ellen Prenger‐Berninghoff, Carsten Heydel, Christa Ewers, Alexander Postel, Nele Gremmel, Paul Becher, Christina Strube, Ursula Siebert   +11 more
wiley   +1 more source

Capabilities of magnetic resonance imaging in the diagnosis of idiopathic inflammatory myopathies

Научно-практическая ревматология
Idiopathic inflammatory myopathies (IIM) are a group of chronic autoimmune conditions characterized by proximal muscle weakness and potentially accompanied by a range of extramuscular clinical manifestations.
A. A. Kolomeychuk
doaj   +1 more source

Defining Pharyngeal and Upper Esophageal Sphincter Disorders on High‐Resolution Manometry‐Impedance: The Leuven Consensus

Neurogastroenterology &Motility, Volume 38, Issue 4, April 2026.
The Leuven Consensus provides a classification scheme for the diagnosis of pharyngeal and upper esophageal sphincter (UES) motor disorders using metrics derived from pharyngeal high‐resolution manometry‐impedance (P‐HRM‐I). These recommendations complement routine instrumental investigations and provide a standardized process, criteria, and ...
Taher I. Omari, Julia C. F. Maclean, Charles Cock, Timothy M. McCulloch, Nogah Nativ‐Zeltzer, Ashli K. O'Rourke, Michal M. Szczesniak, Peter I. Wu, Jacqueline Allen, Yoichiro Aoyagi, Howell Henrian G. Bayona, Silvia Carrión, Michelle R. Ciucci, Kate Davidson, Shumon I. Dhar, Shaheen Hamdy, Rebecca Howell, Corrine Jones, Molly A. Knigge, An Moonen, Gregory N. Postma, Jo Puntil‐Sheltman, Anais Rameau, Julie Regan, Mistyka Schar, Nathalie Rommel   +25 more
wiley   +1 more source

Inclusion body myositis

Canadian Medical Association Journal
Warman-Chardon, Jodi, Breiner, Ari, Bourque, Pierre R.   +2 more
openaire   +3 more sources

Proteomic profiles in inclusion body myositis and polymyositis with mitochondrial pathology

Acta Neuropathologica Communications
Background Idiopathic inflammatory myopathies (IIMs) are autoimmune muscle diseases with distinct clinical, histopathological, and molecular features. Among them, inclusion body myositis (IBM) is refractory to immunotherapy and characterized by combined ...
Felix Kleefeld, Christina B. Schroeter, Donya Abdennebi, Vera Dobelmann, Sara Walli, Andreas Roos, Ute Distler, Stefan Tenzer, Tobias Bopp, Paula Quint, Linda-Isabell Schmitt, Markus Leo, Tim Hagenacker, Iago Pinal-Fernandez, Maria Casal-Dominguez, Andrew L. Mammen, Corinna Preuße, Lorenzo Maggi, Alexander Mensch, Sven G. Meuth, Werner Stenzel, Tobias Ruck, Christopher Nelke   +22 more
doaj   +1 more source

Multi-omics analysis in inclusion body myositis identifies mir-16 responsible for HLA overexpression

Orphanet Journal of Rare Diseases
Background Inclusion Body Myositis is an acquired muscle disease. Its pathogenesis is unclear due to the co-existence of inflammation, muscle degeneration and mitochondrial dysfunction.
Daphne Wijnbergen, Mridul Johari, Ozan Ozisik, Peter A.C. ‘t Hoen, Friederike Ehrhart, Anaïs Baudot, Chris T. Evelo, Bjarne Udd, Marco Roos, Eleni Mina   +9 more
doaj   +1 more source

Increased plasma amyloid-β protein in sporadic inclusion body myositis [PDF]

, 2009
Abdo, W.F., Mierlo, T. van, Hengstman, G.J.D., Schelhaas, H.J., Engelen, B.G.M. van, Verbeek, M.M.   +5 more
core   +1 more source

Inclusion body myositis — a case based clinicopathological update

Open Medicine, 2014
Bodoki Levente, Vincze Melinda, Griger Zoltán, Csonka Tamás, Murnyák Balázs, Kurucz Andrea, Dankó Katalin, Hortobágyi Tibor   +7 more
doaj   +1 more source