Results 121 to 130 of about 15,582 (230)

Strenuous Exercise Alters Brain Creatine and Glutamate/Glutamine (Glx) in Humans: Evidence From Dynamic 1H‐MRS and 1H‐MRSI

open access: yesThe FASEB Journal, Volume 40, Issue 2, 31 January 2026.
Strenuous exercise induces transient, region‐specific neurochemical changes in the human brain. Dynamic proton magnetic resonance spectroscopy (1H‐MRS) and spectroscopic imaging (1H‐MRSI) revealed reductions in total creatine (tCr), and elevations in glutamate/glutamine (Glx), and lactate (Lac) in frontal and parietal brain regions.
Jedd Pratt   +6 more
wiley   +1 more source

Neurological complications of immune checkpoint inhibitors: what happens when you \u27take the brakes off\u27 the immune system. [PDF]

open access: yes, 2018
Patients with advanced malignancies treated with immune checkpoint inhibitors are at increased risk for developing immune-related neurological complications.
Dalakas, Marinos
core   +1 more source

Interrelation of inflammation and APP in sIBM: IL-1 beta induces accumulation of beta-amyloid in skeletal muscle. [PDF]

open access: yes, 2008
Distinct interrelationships between inflammation and beta-amyloid-associated degeneration, the two major hallmarks of the skeletal muscle pathology in sporadic inclusion body myositis (sIBM), have remained elusive.
Barthel, Konstanze   +5 more
core   +1 more source

Capabilities of magnetic resonance imaging in the diagnosis of idiopathic inflammatory myopathies

open access: yesНаучно-практическая ревматология
Idiopathic inflammatory myopathies (IIM) are a group of chronic autoimmune conditions characterized by proximal muscle weakness and potentially accompanied by a range of extramuscular clinical manifestations.
A. A. Kolomeychuk
doaj   +1 more source

Determining the Characteristic Vocabulary for a Specialized Dictionary using Word2vec and a Directed Crawler [PDF]

open access: yes, 2016
Specialized dictionaries are used to understand concepts in specific domains, especially where those concepts are not part of the general vocabulary, or having meanings that differ from ordinary languages.
Grefenstette, Gregory, Muchemi, Lawrence
core   +3 more sources

Inclusion body myositis

open access: yesCanadian Medical Association Journal
Warman-Chardon, Jodi   +2 more
openaire   +3 more sources

Multi-omics analysis in inclusion body myositis identifies mir-16 responsible for HLA overexpression

open access: yesOrphanet Journal of Rare Diseases
Background Inclusion Body Myositis is an acquired muscle disease. Its pathogenesis is unclear due to the co-existence of inflammation, muscle degeneration and mitochondrial dysfunction.
Daphne Wijnbergen   +9 more
doaj   +1 more source

Desmin forms toxic, seeding-competent amyloid aggregates that persist in muscle fibers [PDF]

open access: yes, 2019
Desmin-associated myofibrillar myopathy (MFM) has pathologic similarities to neurodegeneration-associated protein aggregate diseases. Desmin is an abundant muscle-specific intermediate filament, and disease mutations lead to its aggregation in cells ...
Arhzaouy, Khalid   +6 more
core   +1 more source

Inclusion body myositis — a case based clinicopathological update

open access: yesOpen Medicine, 2014
Bodoki Levente   +7 more
doaj   +1 more source

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