Results 151 to 160 of about 12,955 (195)

Myostatin in tendon maintenance and repair

Growth Factors, 2009
Myostatin, a negative regulator of muscle growth, has recently been found to be expressed in tendons. Myostatin-deficient mice have weak and brittle tendons, which suggest that myostatin could be important for tendon maintenance. Follistatin expression in the callus tissue after tendon transection is influenced by loading.
Pernilla, Eliasson, Therese, Andersson, Jana, Kulas, Petra, Seemann, Per, Aspenberg   +4 more
openaire   +2 more sources

Myostatin: Biology and Clinical Relevance

Mini-Reviews in Medicinal Chemistry, 2006
Myostatin is a negative regulator of muscle mass. Important advances in our understanding of the complex biology of this factor have revealed the therapeutic potential of antagonizing the myostatin pathway. Here we present the rationale for evaluating anti-myostatin therapies in human muscle-wasting disorders.
Carnac, Gilles, Ricaud, Stéphanie, Vernus, Barbara, Bonnieu, Anne   +3 more
openaire   +2 more sources

Identification of the Minimum Peptide from Mouse Myostatin Prodomain for Human Myostatin Inhibition

Journal of Medicinal Chemistry, 2015
Myostatin, an endogenous negative regulator of skeletal muscle mass, is a therapeutic target for muscle atrophic disorders. Here, we identified minimum peptides 2 and 7 to effectively inhibit myostatin activity, which consist of 24 and 23 amino acids, respectively, derived from mouse myostatin prodomain. These peptides, which had the propensity to form
Kentaro, Takayama, Yuri, Noguchi, Shin, Aoki, Shota, Takayama, Momoko, Yoshida, Tomo, Asari, Fumika, Yakushiji, Shin-ichiro, Nishimatsu, Yutaka, Ohsawa, Fumiko, Itoh, Yoichi, Negishi, Yoshihide, Sunada, Yoshio, Hayashi   +12 more
openaire   +2 more sources

REGULATION OF MUSCLE MASS BY MYOSTATIN

Annual Review of Cell and Developmental Biology, 2004
▪ Abstract  Myostatin is a secreted protein that acts as a negative regulator of skeletal muscle mass. During embryogenesis, myostatin is expressed by cells in the myotome and in developing skeletal muscle and acts to regulate the final number of muscle fibers that are formed.
openaire   +2 more sources

Myostatin: An Overlooked Player in Heart Failure?

European Journal of Heart Failure, 2010
Sillje, Herman H. W., de Boer, Rudolf A.
openaire   +1 more source

Myostatin

2012
openaire   +2 more sources

Myostatin

Strength and Conditioning Journal, 2004
openaire   +1 more source

Myostatin and muscle growth

2018
Sello ...
Ferragut Fiol, C., López Calbet, Jóse A.   +1 more
openaire   +1 more source

Measurement of myostatin concentrations in human serum: Circulating concentrations in young and older men and effects of testosterone administration

Molecular and Cellular Endocrinology, 2009
, Andrew J Dörner, Michael E Burczynski
exaly  

Comparison of avian myostatin genes

Animal Genetics, 2004
Z, Gu, Y, Zhang, P, Shi, Y-P, Zhang, D, Zhu, H, Li   +5 more
openaire   +2 more sources