Results 161 to 170 of about 33,582 (263)

Myostatin Exacerbates Endothelial Dysfunction Induced by Uremic Toxin Indoxyl Sulfate and Is Associated with Hemodialysis Arteriovenous Access Complications

Toxins
Hemodialysis patients exhibit endothelial dysfunction, contributing to elevated cardiovascular risk and complications of the arteriovenous access. These patients have elevated serum levels of myostatin, a member of the transforming growth factor-β (TGFβ)
Justine Solignac, Laetitia Dou, Rania Chermiti, Nathalie McKay, Philippe Giaime, Nathalie Pedinielli, Hamza Benjelloun, Guillaume Lano, Julien Mancini, Stéphane Burtey, Stanislas Bataille   +10 more
doaj   +1 more source

Impact of obesity and an obesogenic environment on cardiotoxin‐induced damage and recovery of human myotubes

Experimental Physiology, Volume 111, Issue 4, Page 2073-2085, 1 April 2026.
Abstract Obesity (BMI ≥ 30 kg/m2) reduces skeletal muscle quality and impairs the myogenic response to muscle damage. The present study investigated if differences exist in myotubes from individuals with (OB) or without (LN) obesity incubated in control (bovine serum albumin [BSA]) or obesogenic (Ob) medium, at baseline or in response to cardiotoxin ...
Brian P. Sullivan, Lundon C. Burton, Allison Ellis, Christopher K. Kargl, Deborah Shera, Shihuan Kuang, James F. Markworth, Timothy P. Gavin   +7 more
wiley   +1 more source

Serum level of myostatin and type I interferon-inducible gene expression in dermatomyositis patients and its relation to insulin resistance

The Egyptian Journal of Neurology, Psychiatry and Neurosurgery
Background Data regarding the relation between serum myostatin level, type I interferon-inducible gene expression and insulin resistance in dermatomyositis patients are limited.
Rania S. Nageeb, Noura Mostafa Mohamed, Ahmad Sallam Soliman, Amany M. Ebaid, Nancy Abdelhamid Mohammad   +4 more
doaj   +1 more source

The skeletal muscle–adipose creatine metabolic axis: A novel paradigm for lipid metabolism reprogramming and obesity management

Experimental Physiology, Volume 111, Issue 4, Page 1700-1707, 1 April 2026.
Abstract The global prevalence of obesity and related metabolic disorders has spurred interdisciplinary research to develop new intervention strategies. Current research is increasingly focusing on the exercise‐induced browning of white adipose tissue and the mechanisms by which it improves energy metabolism.
Yuhui Su, Na Liu, Yang Liu, Yiqun Sun, Yike Jiao   +4 more
wiley   +1 more source

Correlations of serum myostatin and irisin with sarcopenia and osteoporosis in rheumatoid arthritis patients: a cross-sectional study

Scientific Reports
Myostatin and irisin, the key regulators of muscle metabolism, are myokines secreted by skeletal muscles that significantly influence osteoporosis (OP) and sarcopenia.
Wan-jun Li, Ruo-yan-ran Yin, Xiao-xuan Xia, Qian-xi Xing, Sheng-qian Xu   +4 more
doaj   +1 more source

Mechanisms of myostatin and activin A accumulation in chronic kidney disease.

Nephrology, Dialysis and Transplantation, 2022
Stanislas Bataille, Laetitia Dou, Marcello Bartoli, M. Sallée, J. Aniort, Bohrane Ferkak, Rania Chermiti, N. Mckay, Nathalie Da Silva, S. Burtey, S. Poitevin   +10 more
semanticscholar   +1 more source

A Limousin Specific Myostatin Allele Affects Longissimus Muscle Area and Fatty Acid Profiles in a Wagyu-Limousin F2 Population [PDF]

, 2009
A microsatellite-based genome scan of a Wagyu x Limousin F(2) cross population previously demonstrated QTL affecting LM area and fatty acid composition were present in regions near the centromere of BTA2.
Alexander, L. J., Geary, T. W., Koltes, J. E., Kuehn, L. A., MacNeil, M. D., Matukumalli, L. K., Mote, B., Reecy, James, Reecy, James, Rule, D. C., Smtih, T. P. L.   +10 more
core   +2 more sources

Acute hypoxia reduces plasma myostatin independent of hypoxic dose [PDF]

, 2015
Background: Muscle atrophy is seen ~ 25 % of patients with cardiopulmonary disorders, such as chronic obstructive pulmonary disorder and chronic heart failure.
Elliott, B., Elliott, B., Getting, S.J., Getting, S.J., MacKenzie, R., MacKenzie, R., Renshaw, D., Renshaw, D., Simonson, T.S., Simonson, T.S., Wagner Peter, D., Wagner Peter, D.   +11 more
core  

Blocking myostatin [PDF]

Genome Biology, 2002
openaire   +1 more source

Anti-myostatin antibody therapy for myopathies

Rinsho Shinkeigaku, 2011
Myostatin, a member of the muscle-specific transforming growth factor (TGF)-β family, negatively regulates skeletal muscle growth. It inhibits muscle stem cell proliferation and differentiation, and attenuates adult muscle fiber protein accretion, resulting in decreased skeletal muscle mass.
openaire   +3 more sources