Results 71 to 80 of about 26,633 (217)

Guidance for Liver Rehabilitation in Chronic Liver Disease

Hepatology Research, EarlyView.
ABSTRACT In April 2023, the Japan Society of Hepatology published its official guidelines on liver rehabilitation for chronic liver disease. In this article, we summarize the current evidence on the role of liver rehabilitation in slowing the progression of chronic liver disease, particularly metabolic dysfunction‐associated steatotic liver disease ...
Shuji Terai, Hiroteru Kamimura, Yoichi Hiasa, Norio Akuta, Toru Ishikawa, Yuichiro Eguchi, Hironao Okubo, Takumi Kawaguchi, Miwa Kawanaka, Tatsuo Kanda, Masaaki Korenaga, Ryotaro Sakamori, Masahito Shimizu, Yoshio Sumida, Ryosuke Tateishi, Atsushi Tanaka, Naoki Tanaka, Yasuo Tanaka, Yuki Tahata, Masato Nakai, Tadashi Namisaki, Takashi Nishimura, Atsushi Hiraoka, Takeshi Matsui, Nami Mori, Akio Moriya, Tetsuo Takehara   +26 more
wiley   +1 more source

Cord blood myostatin concentrations by gestational diabetes mellitus and fetal sex

Frontiers in Endocrinology, 2023
IntroductionMyostatin is a member of the transforming growth factor β superfamily, and is mainly secreted from skeletal muscle. Animal studies have demonstrated that deficiency in myostatin promotes muscle growth and protects against insulin resistance ...
Rong Huang, Rong Huang, Mark Kibschull, Laurent Briollais, Laurent Briollais, Zdenka Pausova, Zdenka Pausova, Kellie Murphy, Kellie Murphy, John Kingdom, John Kingdom, Stephen Lye, Stephen Lye, Zhong-Cheng Luo, Zhong-Cheng Luo   +14 more
doaj   +1 more source

Genomic Analysis of Inbreeding Depression on Productive Traits in Rubia Galega Beef Cattle Breed

Journal of Animal Breeding and Genetics, EarlyView.
ABSTRACT In autochthonous livestock breeds with small populations, such as the Rubia Galega from Galicia (Spain), mating between relatives is common and can lead to inbreeding depression. Genomic inbreeding coefficients were estimated for 4984 animals using ~63,000 SNPs to assess inbreeding depression in four key traits: age at first calving (AFC) with
N. Mejuto‐Vázquez, C. Hervás‐Rivero, R. Rodríguez‐Bermúdez, D. López‐Carbonell, M. Hermida, P. Martínez, L. Varona   +6 more
wiley   +1 more source

Development of antisense-mediated myostatin knockdown for the treatment of insulin resistance

Scientific Reports, 2021
Myostatin is a negative regulator of muscle mass and its inhibition represents a promising strategy for the treatment of muscle disorders and type 2 diabetes.
Wouter Eilers, Mark Cleasby, Keith Foster   +2 more
doaj   +1 more source

Endocrine‐Nutritional Synergy Between Sex Inversion and Microencapsulated Bioactives Enhances Growth, Intestinal Development, and Oxidative Stability in Nile Tilapia Larvae

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT This study evaluated the combined effects of sex inversion and microencapsulated supplementation with organic acids and essential oils on growth performance, tissue morphology, gene expression, and oxidative status in Nile tilapia (Oreochromis niloticus) larvae.
Jaísa Casetta, Eliane Gasparino, Caroline Isabela da Silva, Simone Siemer, Gabriela Hernandes Cangianelli, Ricardo Souza Vasconcellos, Ricardo Pereira Ribeiro, Graciele Caroline Mari, Jaqueline Roesler, Juliana Sofientini, Diogo de Oliveira Marques, Stefania Claudino‐Silva   +11 more
wiley   +1 more source

Understanding Impact of Anti‐Obesity Medications on Skeletal Muscle Mass Change Is Confounded by Measurement Methods

Obesity Reviews, EarlyView.
ABSTRACT Anti‐obesity medications promote greater degrees of weight loss than lifestyle interventions alone. There is an important need to understand whether loss of skeletal muscle during pharmacologically induced weight loss is clinically significant due to its essential role in health and disease.
Arden McMath, Dympna Gallagher
wiley   +1 more source

Investigating mechanisms underpinning the detrimental impact of a high-fat diet in the developing and adult hypermuscular myostatin null mouse [PDF]

, 2015
Background: Obese adults are prone to develop metabolic and cardiovascular diseases. Furthermore, over-weight expectant mothers give birth to large babies who also have increased likelihood of developing metabolic and cardiovascular diseases. Fundamental
A Matsakas, A Matsakas, A Matsakas, A Matsakas, A Raben, A Roca-Rivada, AC McPherron, AC McPherron, AD Kriketos, AD Kriketos, AJ Wade, B Zhao, BC Song, C Cooper, C Zhang, CE Brown, CL Mendias, CN Hales, DJ Barker, DJ Barker, DS Mosher, ED Rosen, F Backhed, F Zurlo, G Aldini, G Liebisch, GP Holloway, GP Holloway, H Abe, H Amthor, H Lees, J Abou Mrad, J He, JF Tong, JP Thyfault, JR Swann, JT Tansey, K Relizani, KM Chan, KR Westerterp, M Qatanani, M Scherer, M Scherer, M Schuelke, MW Hamrick, O Beckonert, P Bostrom, Q Wang, R Kohen, RE Williams, RM Avena, S Girgenrath, T Guo, T Westergaard, T Westergaard, T Westergaard, TP Ciaraldi, V Matyash, VA Narkar, YX Wang   +59 more
core   +2 more sources

Increased plasma myostatin in heart failure [PDF]

European Journal of Heart Failure, 2011
Myostatin (Mstn), a member of the transforming growth factors (TGF)-β family that regulate skeletal muscle growth, has been identified as a regulator of cardiomyocyte growth. The aim of our study was to measure Mstn plasma concentrations in patients with congestive heart failure (CHF) and to evaluate their relationship with other neurohormones released
Damien, Gruson, Sylvie A, Ahn, Jean-Marie, Ketelslegers, Michel F, Rousseau   +3 more
openaire   +2 more sources

Locomotor muscle dysfunction and rehabilitative exercise training in fibrotic interstitial lung disease: Where are we at and where could we go?

Experimental Physiology, EarlyView.
Abstract Exercise limitation is a cardinal feature of fibrotic interstitial lung disease arising from pulmonary gas exchange, respiratory mechanical and cardio‐circulatory abnormalities. More recently, it has been recognized that impairment in locomotor muscle function (e.g., reduced muscle mass/strength or heightened fatigability) might also play a ...
Sarah Thivent, J. Alberto Neder, Anne‐Catherine Bernard, Marie Coudurier, Michel Guinot, Frédéric Hérengt, Samuel Verges, Mathieu Marillier   +7 more
wiley   +1 more source

Healthy community‐living older men differ from women in associations between myostatin levels and skeletal muscle mass

Journal of Cachexia, Sarcopenia and Muscle, 2018
Background Myostatin is a negative regulator of muscle growth but the relationship between serum myostatin levels and muscle mass is unclear. This study investigated the association between serum myostatin levels and skeletal muscle mass among healthy ...
Li‐Ning Peng, Wei‐Ju Lee, Li‐Kuo Liu, Ming‐Hsien Lin, Liang‐Kung Chen   +4 more
doaj   +1 more source