Results 91 to 100 of about 2,019 (200)
The FASEB Journal, Volume 38, Issue 22, 30 November 2024.Optogenetic tools like Channelrhodpsin‐2 (ChR2) are useful for inducing skeletal muscle contraction using blue light. However, the prevalence of fluorescent proteins like EYFP may cause functional issues. Here, Lamia et al. showed that the contractile properties of ChR2‐EYFP skeletal muscle had aggregated EYFP in sarcolemma, decreased contractile force
Syeda N. Lamia +13 more
wiley +1 more source
, 2022 DM64 is a toxin-neutralizing serum glycoprotein isolated from Didelphis aurita, an ophiophagous marsupial naturally resistant to snake envenomation. This 64 kDa antitoxin targets myotoxic phospholipases A2, which account for most local tissue damage of ...
Thomas J. D. Jørgensen (8862011) +16 more
core +1 more source
Physiological Reports, Volume 12, Issue 18, September 2024.Abstract The use of tobacco cigarettes produces locomotor muscle weakness and fatigue intolerance. Also, smokers and chronic obstructive pulmonary disease patients have a greater incidence of muscle injury and a deficient myogenic response. However, the effects of smoke exposure on the recovery from eccentric exercise‐induced muscle injuries are ...
Nicole E. Stevens +6 more
wiley +1 more source
Revista do Instituto de Medicina Tropical de São Paulo, 1992 A mionecrose é um dos efeitos causados pelo veneno de Bothrops jararacussu. Uma miotoxina com homologia estrutural à fosfolipase A2 (PLA2), mas sem atividade enzimática, foi isolada desse veneno.
Maria Cristina dos-Santos +5 more
doaj +1 more source
Snake venom toxins: Potential anticancer therapeutics
Journal of Applied Toxicology, Volume 44, Issue 5, Page 666-685, May 2024.Abstract Snake venom contains a cocktail of compounds dominated by proteins and peptides, which make up the toxin. The toxin components of snake venom attack several targets in the human body including the neuromuscular system, kidney and blood coagulation system and cause pathologies. As such, the venom toxins can be managed and used for the treatment
Benedict C. Offor, Lizelle A. Piater
wiley +1 more source
The venom-gland transcriptome of the eastern diamondback rattlesnake (
BMC Genomics, 2012 Background Snake venoms have significant impacts on human populations through the morbidity and mortality associated with snakebites and as sources of drugs, drug leads, and physiological research tools.
Rokyta Darin R +3 more
doaj +1 more source
, 2022 DM64 is a toxin-neutralizing serum glycoprotein isolated from Didelphis aurita, an ophiophagous marsupial naturally resistant to snake envenomation. This 64 kDa antitoxin targets myotoxic phospholipases A2, which account for most local tissue damage of ...
Thomas J. D. Jørgensen (8862011) +16 more
core +1 more source
Mediators of Inflammation, 2002 Envenomations by the snake Bothrops asper are characterized by prominent local tissue damage (i.e. myonecrosis), blistering, hemorrhage and edema. Various phospholipases A2 and metalloproteinases that induce local pathological alterations have been ...
Alexandra Rucavado +5 more
doaj +1 more source
, 1990 Equine antibodies to B. riper myotoxin II were isolated from polyvalent antivenom by affinity chromatography. Purified antibodies were among the most acidic serum immunoglobulins, migrating between the ß- and aZ-globulin regions by zone ...
Carmona Morera, Elena +3 more
core +1 more source
A new muscle damaging toxin, myotoxin II, from the venom of the snake Bothrops asper (terciopelo)
, 1989 A new muscle damaging toxin, myotoxin II, was purified from the venom of Bothrops asper by ion-exchange chromatography on CMSephadex C-25. The toxin is a dimeric, basic protein with a monomer mol.wt of 13,341, according to the amino acid composition, and
Lomonte, Bruno, Gutiérrez, José María
core +1 more source