Results 81 to 90 of about 2,019 (200)
, 1994 This meeting abstract discusses the Characterization of the effects of depolarizing phospholipases a(2), myotoxin a and ouabain on the perineural waveforms recorded from mouse motor nerve ...
Fatehi, M., Harvey, A.L., Rowan, E.G.
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The FASEB Journal, Volume 39, Issue 20, 31 October 2025.The figure illustrates in vitro (melatonin‐treated C2C12 myoblasts) and in vivo (mouse frostbite‐induced tibialis anterior muscle injury with melatonin administration) models. Melatonin activates AMPK, which phosphorylates PGC‐1α to enhance mitochondrial bioenergetics (decreased ROS and LDH, increased ATP, mtDNA, membrane potential, and oxygen ...
Wei Xie +8 more
wiley +1 more source
, 1995 Myotoxin α (MYTX), a polypeptide toxin purified from the venom of prairie rattlesnakes (Crotalus viridis viridis), induced Ca2+release from the heavy fraction of skeletal sarcoplasmic reticulum (HSR), using a Ca2+electrode.
Masamichi Ohkura +5 more
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Discovery of peptidic anti-myotoxins [PDF]
, 2016 More than 2.5 millions envenomations and 125.000 death occur each year due to snakebite. Current antivenoms consist of immunoglobulinesderived from animals, and they are therefore associated with a high risk of adverse reactions in humans. The use of synthetic peptidic antitoxinsmay lead to safer and more effective antivenoms. This research reports the
Bjärtun, Johanna +4 more
openaire
Pathogenesis of myonecrosis induced by crude venom and a myotoxin of Bothrops asper
Experimental and Molecular Pathology, 1984 The pathogenesis of skeletal muscle necrosis induced by crude Bothrops asper venom and isolated myotoxic phospholipase was studied using light and electron microscopy. White mice were injected intramuscularly with a dose of 2.5 micrograms/g and tissue samples were taken at 30 min and 1, 3, 6, 12, 24, and 48 hr.
Ownby, Charlotte L. +2 more
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Synapse, Volume 79, Issue 4, July 2025.A neuromuscular junction (NMJ) imaged with pre‐ and postsynaptic features seen with immunofluorescent staining along with confocal microscopy. The article presented here confirms the importance of regaining proper posttraumatic NMJ structure to enable reestablishment of healthy skeletal muscle mass and how the presence of mitochondrial matter promotes ...
Michael R. Deschenes +7 more
wiley +1 more source
Myotoxin II from Bothrops asper (Terciopelo) venom is a lysine-49 phospholipase A2
, 1991 A basic, dimeric myotoxic protein, myotoxin II, purified from Bothrops asper venom has a similar molecular weight and is immunologically cross-reactive with antibodies raised to previously isolated B.
Francis, Brian +3 more
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, 2022 DM64 is a toxin-neutralizing serum glycoprotein isolated from Didelphis aurita, an ophiophagous marsupial naturally resistant to snake envenomation. This 64 kDa antitoxin targets myotoxic phospholipases A2, which account for most local tissue damage of ...
Thomas J. D. Jørgensen (8862011) +16 more
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MyoD Overexpressed Equine Adipose-Derived Stem Cells Enhanced Myogenic Differentiation Potential
Cell Transplantation, 2016 Mesenchymal stem cells could potentially be used in the clinical treatment of muscle disorders and muscle regeneration. Adipose-derived stem cells (ADSCs) can be easily isolated from adipose tissue, as opposed to stem cells of other tissues.
Soo-Eun Sung +8 more
doaj +1 more source
Renal lesions in rhabdomyolysis caused by Pseudechis australis snake myotoxin
Kidney International, 1997 The renal lesions at various time intervals after i.m. injection of Pseudechis australis myotoxin (PA myotoxin) causing myoglobinuria in mice was studied. Biochemical assay of serum creatine phosphokinase (CK) and lactate dehydrogenase (LDH) showed marked elevations [7166 +/- 2064 IU and 1626 +/- 211 Berger-Broida U/ml (B-B U/ml)] six hours after ...
Ponraj, D., Gopalakrishnakone, P.
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