Results 41 to 50 of about 4,502 (185)

Ayahuasca and Its DMT- and β-carbolines – Containing Ingredients Block the Expression of Ethanol-Induced Conditioned Place Preference in Mice: Role of the Treatment Environment

Frontiers in Pharmacology, 2018
Ayahuasca is a hallucinogenic beverage produced from the decoction of Banisteriopsis caapi (Bc) and Psychotria viridis (Pv), β-carboline- and N,N-dimethyltryptamine(DMT)-containing plants, respectively.
Elisangela G. Cata-Preta, Yasmim A. Serra, Eliseu da C. Moreira-Junior, Henrique S. Reis, Natali D. Kisaki, Matheus Libarino-Santos, Raiany R. R. Silva, Thaísa Barros-Santos, Lucas C. Santos, Paulo C. R. Barbosa, José L. Costa, Alexandre J. Oliveira-Lima, Lais F. Berro, Eduardo A. V. Marinho   +13 more
doaj   +1 more source

Novel psychoactive substances of interest for psychiatry [PDF]

, 2015
Novel psychoactive substances include synthetic cannabinoids, cathinone derivatives, psychedelic phenethylamines, novel stimulants, synthetic opioids, tryptamine derivatives, phencyclidine-like dissociatives, piperazines, GABA-A/B receptor agonists, a ...
Corkery, John, Orsolini, Laura, Papanti, Duccio, Schifano, Fabrizio   +3 more
core   +1 more source

Marine Inspired 2-(5-Halo-1H-indol-3-yl)-N,N-dimethylethanamines as Modulators of Serotonin Receptors: An Example Illustrating the Power of Bromine as Part of the Uniquely Marine Chemical Space

Marine Drugs, 2017
In previous studies, we have isolated several marine indole alkaloids and evaluated them in the forced swim test (FST) and locomotor activity test, revealing their potential as antidepressant and sedative drug leads.
Mohamed A. Ibrahim, Abir T. El-Alfy, Kelly Ezel, Mohamed O. Radwan, Abbas G. Shilabin, Anna J. Kochanowska-Karamyan, Howaida I. Abd-Alla, Masami Otsuka, Mark T. Hamann   +8 more
doaj   +1 more source

Chronic intermittent exposure to ayahuasca during aging does not affect memory in mice

Brazilian Journal of Medical and Biological Research
The Quechua term ayahuasca refers to a beverage obtained from decoctions of the liana Banisteriopsis caapi with leaves of Psychotria viridis. The ritualistic use of ayahuasca is becoming a global phenomenon, with some individuals using this beverage ...
N.F. Correa-Netto, L.S. Coelho, G.S. Galfano, F. Nishide, F. Tamura, M.K. Shimizu, J.G. Santos Junior, A. Linardi   +7 more
doaj   +1 more source

DMT Models the Near-Death Experience

Frontiers in Psychology, 2018
Near-death experiences (NDEs) are complex subjective experiences, which have been previously associated with the psychedelic experience and more specifically with the experience induced by the potent serotonergic, N,N-Dimethyltryptamine (DMT).
Christopher Timmermann, Christopher Timmermann, Leor Roseman, Leor Roseman, Luke Williams, David Erritzoe, Charlotte Martial, Héléna Cassol, Steven Laureys, David Nutt, Robin Carhart-Harris   +10 more
doaj   +1 more source

Nonlinear Pharmacokinetics of 5-Methoxy-N,N-dimethyltryptamine in Mice [PDF]

Drug Metabolism and Disposition, 2011
5-Methoxy-N,N,-dimethyltryptamine (5-MeO-DMT), an abused serotonergic indolealkylamine drug, was placed into Schedule I controlled substance status in the United States as of January 19, 2011. In previous studies, we have shown the impact of monoamine oxidase A and cytochrome P450 2D6 enzymes on 5-MeO-DMT metabolism and pharmacokinetics.
Hong-Wu, Shen, Xi-Ling, Jiang, Ai-Ming, Yu   +2 more
openaire   +2 more sources

Novel Psychoactive Substances 14Recent Progress on Neuropharmacological Mechanisms of Action for Selected Drugs [PDF]

, 2017
A feature of human culture is that we can learn to consume chemical compounds, derived from natural plants or synthetic fabrication, for their psychoactive effects.
Boris B. , Quednow, Christian P. , Müller, Erich, Seifritz, Hassan, Zurina, Johannes, Kornhuber, Kasinather, B. Vicknasingam, Narayanan, Suresh, Oliver G., Bosch, Singh, Darshan   +8 more
core   +1 more source

Epidemiology of classic psychedelic substances: results from a Norwegian internet convenience sample

Frontiers in Psychiatry, 2023
ObjectiveIn recent years, there has been a renewed interest in investigating the use of classic psychedelics such as psilocybin and lysergic acid diethylamide (LSD) in the treatment of mental disorders and substance use disorders.
Tor-Morten Kvam, Tor-Morten Kvam, Malin V. Uthaug, Malin V. Uthaug, Malin V. Uthaug, Kristoffer A. A. Andersen, Kristoffer A. A. Andersen, Birk Berggrav Refsum, Paula Aarseth Tunstad, Lowan Han Stewart, Henrik Børsting Jacobsen, Henrik Børsting Jacobsen, Cato Grønnerød   +12 more
doaj   +1 more source

Psychedelic‐assisted treatment for substance use disorder: A narrative systematic review

Addiction, EarlyView.
Abstract Background and aims This is the first systematic review of the extant literature on all major psychedelic‐assisted treatment for alcohol use disorder (AUD), tobacco use disorder (TUD) and other substance use disorders (SUD). We aimed to summarise the evidence for efficacy of psychedelic‐assisted treatment for AUD, TUD, and SUD; to evaluate its
Theodore Piper, Francesca Small, Sam Brown, Michael Kelleher, Luke Mitcheson, James Rucker, Allan H. Young, John Marsden   +7 more
wiley   +1 more source

Hallucinogen Rating Scale (HRS) - A Brazilian version: translation and cross-cultural adaptation [PDF]

, 2011
BACKGROUND: There is a growing scientific interest in the effects of hallucinogens in general and the religious use of psychoactive brew ayahuasca in Brazil in particular.
Barbosa, Paulo César Ribeiro, Mizumoto, Suely, Silveira, Dartiu Xavier da, Strassman, Rick J.   +3 more
core   +3 more sources