Results 111 to 120 of about 37,494,510 (234)
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
A propósito del asesinato de Fuentealba: El discurso de poder en Sobish
Desde el Análisis Crítico del Discurso, el presente trabajo analiza la solicitada que Jorge Omar Sobisch, Gobernador de la Provincia del Neuquén publicó en los periódicos nacionales el 13 de abril de 2007, luego de la muerte del Maestro Carlos Fuentealba
Delia Cejas +3 more
doaj
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Formas de subsistencia en barrio Luján de Villa Constitución
Nuestro trabajo consistió en primera instancia en observar las condiciones sociales en las que vivían y viven los habitantes de Barrio Luján. Si bien este barrio está denominado con este rótulo, tiene todas las características de una villa, en cuanto a ...
Nadia Alejandra Abrigo +3 more
doaj
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Fil: Consejo Superior de Programación y Gestión Estratégica (P). Universidad Nacional de Río Negro. Río Negro, ArgentinaResolución CSPyGE N° 19/2021. Modificar el ítem "— Bienes recibidos por donaciones de terceros Artículo 3°, de la Resolución CSPyGE N°
Consejo Superior de Programación y Gestión Estratégica (P)
core
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Ato n. 51/TST.GP, de 3 de fevereiro de 2026
Designa membros para integrarem o Comitê de Governança de Gestão Estratégica do Tribunal Superior do Trabalho (CGGE), em atenção ao art. 17, incisos V, VI e VII do Ato n. 478/TST.GP, de 3 de setembro de 2024.Revoga o Ato n.
Brasil. Tribunal Superior do Trabalho (TST)
core +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source

