Results 211 to 220 of about 37,843,783 (322)

Effects of n-3 Long-Chain Polyunsaturated Fatty Acid and Vitamin D Supplementation on Transcriptional Profiles of Human Lung Organoids. [PDF]

Metabolites
Ali M, Mortensen MS, Bæk O, Brustad N, Wang T, Chen L, Kim M, Pedersen CT, Lawley TD, Pasias A, Sedzinski J, Stokholm J, Bønnelykke K, Chawes B.   +13 more
europepmc   +1 more source

La cuestión del Estado hoy

Estudios Sociales del Estado, 2016
Editorial N° 3
doaj   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

High concentrations of polyunsaturated n-3 fatty acids in serum are inversely associated with risk of future incident venous thromboembolism - the HUNT cohort study. [PDF]

Am J Clin Nutr
Johansson M, Brækkan SK, Giskeødegård GF, Wade KH, Hindberg KD, Timpson N, Davey Smith G, Hveem K, Åsvold BO, Brumpton BM, Hansen JB.   +10 more
europepmc   +1 more source

Importance of n-3 fatty acids in health and disease.

American Journal of Clinical Nutrition, 2000
W. Connor
semanticscholar   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Bioreduction of N-(3-oxobutyl)heterocycles with flexible ring by yeast whole-cell biocatalysts. [PDF]

Appl Microbiol Biotechnol
Honvári MG, Kucsinka BA, Mócza LA, Csuka P, Bódai V, Poppe L, Hornyánszky G.   +6 more
europepmc   +1 more source

n°3

, 2017
Simons, Germain, Beckers, Jacqueline, Poffé, Corentin, De Croix, Séverine   +3 more
openaire   +1 more source

n-3 fatty acids and cardiovascular outcomes in patients with dysglycemia.

New England Journal of Medicine, 2012
J. Bosch, H. Gerstein, G. Dagenais, R. Diaz, L. Dyal, Hyejung Jung, Aldo P Maggiono, J. Probstfield, Ambady Ramachandran, M. Riddle, L. Rydén, S. Yusuf   +11 more
semanticscholar   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source