Results 71 to 80 of about 37,494,510 (234)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

N-(3-bromophenyl)acetamide

open access: yes, 2018
This dataset contains experimental data from a sample (N-(3-bromophenyl)acetamide, InChI=1S/C8H8BrNO/c1-6(11)10-8-4-2-3-7(9)5-8/h2-5H,1H3,(H,10,11)).
Wippert, Nicolai
core   +1 more source

Indice General N°3

open access: yesJournal de Ciencias Sociales, 2014
Número 3. Diciembre 2014 Presentación del número 3. Graciela H. Tonon El nacionalismo en los Balcanes. La creación de naciones a un alto precio. Horacio Sánchez Mariño.
Graciela Tonon
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Tuumorispesifisen aldehydidehydrogenaasi-3:n alueellinen ilmentyminen maksassa

open access: yes, 1997
Tuumorispesifinen aldehydidehydrogenaasi, ALDH-3, ilmentyy jyrsijän maksassa karsinogeenialtistuksen jälkeen. ALDH3 kuuluu myös vierasaine-aineenvaihduntaan osallistuvien geenituotteiden ryhmään, joiden ilmentymän säätely välittyy ns. Ah (aryylihiilivety)
Järveläinen, Harri
core  

Editorial (RDPDF, vol. 3, n. 3, 2021)

open access: yesRevista da Defensoria Pública do Distrito Federal, 2021
A Revista da Defensoria Pública do Distrito Federal (RDPDF) apresenta o terceiro número de 2021, composto por artigos que se debruçaram sobre o dossiê temático “Violência e direito: discussões teóricas e práxis”. Concretizando o objetivo institucional
Alberto Carvalho Amaral
doaj  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Ato n. 168/GP, de 3 de abril de 2014

open access: yes, 2014
Altera a redação do art. 2º, do art. 3º e seu § 1º e do § 1º do art. 6º do Ato n. 786/GP, de 3 de dezembro de 2012, que institui o Sistema de Gestão Estratégica do Tribunal Superior do Trabalho (SIGEST).Determina a republicação do Ato n.
Brasil. Tribunal Superior do Trabalho (TST)
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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