Results 41 to 50 of about 14,734,718 (295)

The Multifaceted Therapeutic Role of N-Acetylcysteine (NAC) in Disorders Characterized by Oxidative Stress

open access: yesCurrent Neuropharmacology, 2020
Oxidative stress, which results in the damage of diverse biological molecules, is a ubiquitous cellular process implicated in the etiology of many illnesses.
G. Raghu   +8 more
semanticscholar   +1 more source

Effects of N-acetylcysteine on growth, viability and reactive oxygen species levels in small antral follicles cultured in vitro

open access: yesAsian Pacific Journal of Reproduction, 2023
Objective: To investigate the effects of different concentrations of N-acetylcysteine on follicular growth and morphology, as well as on viability, levels of reactive oxygen species (ROS) and meiotic progression of oocytes from in vitro cultured bovine ...
Efigênia B Cordeiro   +6 more
doaj   +1 more source

N-Acetylcysteine to Combat COVID-19: An Evidence Review

open access: yesTherapeutics and Clinical Risk Management, 2020
The novel coronavirus disease (COVID-19) is caused by a virus (SARS-Cov-2) and is known for inducing multisystem organ dysfunction associated with significant morbidity and mortality. Current therapeutic strategies for COVID-19 have failed to effectively
Zhongcheng Shi, Carlos A Puyo
semanticscholar   +1 more source

N-acetylcysteine in dermatology

open access: yesIndian Journal of Dermatology, Venereology and Leprology, 2018
N-acetylcysteine is a mucolytic drug which is commonly used as an antidote for acetaminophen toxicity. It is a thiol compound, which acts as a donor of cysteine, leading to replenishment of glutathione and thus acts as an antioxidant. It also has anti-inflammatory effects, alters the levels of neurotransmitters, inhibits proliferation of fibroblasts ...
Mohammad, Adil   +2 more
openaire   +2 more sources

Prednisone, Azathioprine, and N-Acetylcysteine for Pulmonary Fibrosis

open access: yesNew England Journal of Medicine, 2012
BACKGROUND A combination of prednisone, azathioprine, and N-acetylcysteine (NAC) has been widely used as a treatment for idiopathic pulmonary fibrosis. The safety and efficacy of this three-drug regimen is unknown.
G. Raghu   +4 more
semanticscholar   +1 more source

N-Acetylcysteine causes analgesia in a mouse model of painful diabetic neuropathy

open access: yesMolecular Pain, 2020
N-Acetylcysteine, one of the most prescribed antioxidant drugs, enhances pain threshold in rodents and humans by activating mGlu2 metabotropic glutamate receptors.
Serena Notartomaso   +10 more
doaj   +1 more source

Two contradictory facades of N-acetylcysteine activity towards renal carcinoma cells

open access: yesJournal of Taibah University for Science, 2022
As a prescribed antioxidant, N-Acetylcysteine is used in treating disease and supportive care. However, N-acetylcysteine’s role in cancer therapy is controversial and needs to be investigated thoroughly. Presently, renal cell carcinoma is one of the most
Zhihai Yu   +6 more
doaj   +1 more source

Therapeutic blockade of inflammation in severe COVID-19 infection with intravenous N-acetylcysteine

open access: yesClinical Immunology, 2020
Glucose 6-phosphate dehydrogenase (G6PD) deficiency facilitates human coronavirus infection due to glutathione depletion. G6PD deficiency may especially predispose to hemolysis upon coronavirus disease-2019 (COVID-19) infection when employing pro-oxidant
Homam Ibrahim   +8 more
semanticscholar   +1 more source

Electrochemical Determination of N-acetylcysteine and Folic Acid in Pharmaceutical and Biological Samples Using a Modified Carbon Nanotube Paste Electrode

open access: yesInternational Journal of Electrochemical Science, 2014
2-chlorobenzoyl ferrocene, was synthesized and used to construct a modified carbon nanotube paste electrode. The electrooxidation of N-acetylcysteine at the surface of the modified electrode was studied.
Mohammad Mehdi Foroughi   +4 more
doaj   +1 more source

Protective effect of N-acetylcysteine in prosthetic joint infection: A nationwide population-based cohort study

open access: yesJournal of Microbiology, Immunology and Infection, 2020
Purpose: This nationwide population-based retrospective cohort study evaluated the protective effect of N-acetylcysteine against prosthetic joint infection after hip or knee joint replacement.
Chan-Yuan Chang   +7 more
doaj   +1 more source

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