N-acetylcysteine in dermatology
Indian Journal of Dermatology, Venereology and Leprology, 2018 N-acetylcysteine is a mucolytic drug which is commonly used as an antidote for acetaminophen toxicity. It is a thiol compound, which acts as a donor of cysteine, leading to replenishment of glutathione and thus acts as an antioxidant. It also has anti-inflammatory effects, alters the levels of neurotransmitters, inhibits proliferation of fibroblasts ...
Mohammad, Adil +2 more
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N-Acetylcysteine causes analgesia in a mouse model of painful diabetic neuropathy
Molecular Pain, 2020 N-Acetylcysteine, one of the most prescribed antioxidant drugs, enhances pain threshold in rodents and humans by activating mGlu2 metabotropic glutamate receptors.
Serena Notartomaso +10 more
doaj +1 more source
Prospective study to compare antibiosis versus the association of N-acetylcysteine, D-mannose and morinda citrifolia fruit extract in preventing urinary tract infections in patients submitted to urodynamic investigation [PDF]
, 2017 BACKGROUND: The abuse of antimicrobical drugs has increased the resistance of microorganisms to treatments, thus to make urinary tract infections (UTIs) more difficult to eradicate.
Al Rawashdah, S +12 more
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International Journal of Electrochemical Science, 2014 2-chlorobenzoyl ferrocene, was synthesized and used to construct a modified carbon nanotube paste electrode. The electrooxidation of N-acetylcysteine at the surface of the modified electrode was studied.
Mohammad Mehdi Foroughi +4 more
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Journal of Microbiology, Immunology and Infection, 2020 Purpose: This nationwide population-based retrospective cohort study evaluated the protective effect of N-acetylcysteine against prosthetic joint infection after hip or knee joint replacement.
Chan-Yuan Chang +7 more
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Antibiofilm effects of mucolytic drugs
Zdorovʹe Rebenka, 2020 Mucolytic drugs have the ability to disrupt the structure of the matrix and destroy the formed bacterial biofilms. The most studied is N-acetylcysteine. Ciro Pérez-Giraldo et al.
А.Е. Abaturov, O.O. Rusakova
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Cardiovascular and hepatic toxicity of cocaine: potential beneficial effects of modulators of oxidative stress [PDF]
, 2015 Oxidative stress (OS) is thought to play an important role in the pharmacological and toxic effects of various drugs of abuse. Herein we review the literature on the mechanisms responsible for the cardiovascular and hepatic toxicity of cocaine with ...
Antonilli, Letizia +5 more
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Effect of N-acetylcysteine on exacerbations of bronchiectasis (BENE): a randomized controlled trial
Respiratory Research, 2019 Background N-acetylcysteine is a classic mucolytic agent. This study aimed to investigate the efficacy of N-acetylcysteine on reducing the risk of exacerbations in bronchiectasis patients. Methods A prospective, randomized, controlled trial was conducted
Qian Qi +8 more
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GSH rescue by N-acetylcysteine [PDF]
Klinische Wochenschrift, 1991 Reduced glutathione (GSH) is the main intracellular low molecular weight thiol. GSH acts as a nucleophilic scavenger and as an enzyme-catalyzed antioxidant in the event of electrophilic/oxidative tissue injury. Therefore, GSH has a major role as a protector of biological structures and functions.
Ruffmann, R., Wendel, A.
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N-acetyl-cysteine, a drug that enhances the endogenous activation of group-II metabotropic glutamate receptors, inhibits nociceptive transmission in humans. [PDF]
, 2015 Emerging research seeking novel analgesic drugs focuses on agents targeting group-II metabotropic glutamate receptors (mGlu2 and mGlu3 receptors). N-Acetylcysteine (NAC) enhances the endogenous activation of mGlu2/3 receptors by activating the glial ...
BATTAGLIA, Giuseppe +8 more
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