Results 31 to 40 of about 14,734,718 (295)

N‐acetylcysteine as a new prominent approach for treating psychiatric disorders

open access: yesBritish Journal of Pharmacology, 2021
N‐acetylcysteine (NAC) is a well‐known and safe mucolytic agent, also used in patients with paracetamol overdose. In addition to these effects, recent preclinical and clinical studies have shown that NAC exerts beneficial effects on different psychiatric
I. Smaga, M. Frankowska, M. Filip
semanticscholar   +1 more source

Influence of N-acetylcysteine on pituitary-gonadal axis hormones and protamine expression level in streptozotocin-induced diabetic male rats

open access: yesAsian Pacific Journal of Reproduction, 2020
Objective: To study the influence of N-acetylcysteine on the pituitary-gonadal axis hormones and protamine expression level in streptozotocin-induced diabetic male rats. Methods: Forty-two adult male Wistar rats were divided into 6 groups, with 7 rats in
Maryam Hassanzadeh Moghadam   +3 more
doaj   +1 more source

N-acetylcysteine modulates cyclophosphamide-induced immunosuppression, liver injury, and oxidative stress in miniature pigs

open access: yesJournal of Animal Science and Technology, 2020
Cyclophosphamide, a cytotoxic anticancer agent, induces immunosuppression and has several adverse effects. N-acetylcysteine alleviates oxidative stress, liver injury, and intestinal tissue damage. The present study
Kyung Soo Kang, Sangsu Shin, Sang In Lee
doaj   +1 more source

High-dose N-acetylcysteine therapy in the treatment of pneumonia

open access: yesPerioperative Medicine, 2021
The article presents modern data on the use of N-acetylcysteine in the treatment of infectious diseases of the respiratory tract in the practice of a physician.
Dmytro Dmytriiev   +2 more
doaj   +1 more source

Alteration of Oxidative stress and apoptotic markers alterations in the rat prefrontal cortex influence behavioral response induced by cisplatin and N-acetylcysteine in the tail suspension test [PDF]

open access: yesJournal of Integrative Neuroscience, 2021
Cisplatin therapy is often accompanied by neurotoxicity manifestation, and since the prefrontal cortex is strongly involved in emotion regulation, the aim of this study was to analyze the alterations in the oxidative and apoptotic status of this brain
Rade Vukovic   +5 more
doaj   +1 more source

N-acetylcysteine as an adjunctive treatment for smoking cessation: a randomized clinical trial [PDF]

open access: yesBrazilian Journal of Psychiatry, 2020
Objective: This randomized controlled trial examined the efficacy and safety of N-acetylcysteine as an adjunctive treatment for smoking cessation. Methods: Heavy smokers were recruited from smoking cessation treatment for this 12- week randomized ...
Regina C.B.R. Machado   +6 more
doaj   +1 more source

N-Acetylcysteine and Hydrogen Sulfide in Coronavirus Disease 2019

open access: yesAntioxidants and Redox Signaling, 2021
Significance: Hydrogen sulfide (H2S) is one of the three main gasotransmitters that are endogenously produced in humans and are protective against oxidative stress.
A. Bourgonje   +7 more
semanticscholar   +1 more source

Protective role of N-acetylcysteine and Sulodexide on endothelial cells exposed on patients’ serum after SARS-CoV-2 infection

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
Severe acute respiratory syndrome coronavirus-2 causes hyperinflammation and activation of coagulation cascade and, as a result, aggravates endothelial cell dysfunction. N-acetylcysteine and Sulodexide have been found to mitigate endothelial damage.
Justyna Rajewska-Tabor   +5 more
doaj   +1 more source

N-Acetylcysteine as Adjuvant Therapy for COVID-19 – A Perspective on the Current State of the Evidence

open access: yesJournal of Inflammation Research, 2021
The looming severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a long-lasting pandemic of coronavirus disease 2019 (COVID-19) around the globe with substantial morbidity and mortality.
K. Wong, Shaun Wen Huey Lee, K. P. Kua
semanticscholar   +1 more source

Uses of n acetylcysteine in dermatology [PDF]

open access: yesAl-Azhar International Medical Journal
N-acetylcysteine (NAC)is a mucolytic drug frequently utilized as an antidote for acetaminophen toxicity.  It is a thiol compound that acts as a cysteine donor, aiding the replenishment of glutathione & acting as an antioxidant.
Sahar Mohamed Ahmed   +3 more
doaj   +1 more source

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