Results 51 to 60 of about 14,734,718 (295)
N-Acetylcysteine: A potential therapeutic agent for SARS-CoV-2
Medical Hypotheses, 2020 COVID-19, a respiratory disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), continues to spread across the globe. Predisposing factors such as age, diabetes, cardiovascular disease, and lowered immune function increase the ...
Francis L. Poe, Joshua Corn
semanticscholar +1 more source
Antibiofilm effects of mucolytic drugs
Zdorovʹe Rebenka, 2020 Mucolytic drugs have the ability to disrupt the structure of the matrix and destroy the formed bacterial biofilms. The most studied is N-acetylcysteine. Ciro Pérez-Giraldo et al.
А.Е. Abaturov, O.O. Rusakova
doaj +1 more source
GSH rescue by N-acetylcysteine [PDF]
Klinische Wochenschrift, 1991 Reduced glutathione (GSH) is the main intracellular low molecular weight thiol. GSH acts as a nucleophilic scavenger and as an enzyme-catalyzed antioxidant in the event of electrophilic/oxidative tissue injury. Therefore, GSH has a major role as a protector of biological structures and functions.
Ruffmann, R., Wendel, A.
openaire +2 more sources
N-acetylcysteine as an adjunct treatment of schizophrenia
European Psychiatry, 2021 Introduction An increasing body of literature supports the hypothesis that immune imbalance towards a pro-inflammatory status in the brain plays an important role in schizophrenia.
R. Mota Freitas, M.T. Valadas
doaj +1 more source
Scientific Reports, 2021 The 1,l/-bis(2-phenylethan-1-ol)ferrocene, 1-butyl-3-methylimidazolium hexafluoro phosphate (BMPF6) and NiO-SWCNTs were used to modify carbon paste electrode (BPOFc/BMPF6/NiO-SWCNTs/CPE), which could act as an electro-catalytic tool for the analysis of N-
Mohsen Keyvanfard +9 more
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The effect of N-acetylcysteine on mechanical fatigue resistance of antibiotic-loaded bone cement
Journal of Orthopaedic Surgery and Research, 2018 Background This biomechanical study evaluates the effect of N-acetylcysteine alone and in combination with the most commonly used antibiotic-loaded bone cement mixtures.
Erhan Sukur +5 more
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N-Acetylcysteine: Antioxidant, Aldehyde Scavenger, and More
Chemical Research in Toxicology, 2019 N-acetylcysteine is a commonly used antioxidant that is broadly effective despite its limited ROS reactivity. Chemoprotection by N-acetylcysteine frequently results from inactivation of primary toxicants or reactive electrophiles arising as metabolites ...
A. Zhitkovich
semanticscholar +1 more source
Safety of N-Acetylcysteine at High Doses in Chronic Respiratory Diseases: A Review
Drug Safety, 2020 N-Acetylcysteine (NAC) is widely used in respiratory medicine, with a maximum licensed dose in chronic use of 600 mg/day; however, some clinical trials have studied the efficacy of NAC at higher doses.
P. Calverley, P. Rogliani, A. Papi
semanticscholar +1 more source
Both PKA and Epac pathways mediate N-acetylcysteine-induced Connexin43 preservation in rats with myocardial infarction. [PDF]
PLoS ONE, 2013 Cardiac remodeling was shown to be associated with reduced gap junction expression after myocardial infarction. A reduction in gap junctional proteins between myocytes may trigger ventricular arrhythmia.
Tsung-Ming Lee +2 more
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Effects of melatonin and N-acetylcysteine on aluminum phosphide poisoning in rats
Journal of Family Medicine and Primary Care, 2022 Introduction: Aluminum phosphide (ALP) poisoning is one of the deadliest types of poisoning in the world. The antioxidant properties of melatonin and N-acetylcysteine and their effects on reducing cell death have been identified.
Ramin Parvizrad +3 more
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