Molecular Mechanisms and Applications of N-Acyl Homoserine Lactone-Mediated Quorum Sensing in Bacteria. [PDF]
Microbial biodiversity includes biotic and abiotic components that support all life forms by adapting to environmental conditions. Climate change, pollution, human activity, and natural calamities affect microbial biodiversity. Microbes have diverse growth conditions, physiology, and metabolism. Bacteria use signaling systems such as quorum sensing (QS)
Kumar L +8 more
europepmc +6 more sources
Synthesis and analysis of stable isotope-labelled N-acyl homoserine lactones [PDF]
Aliphatic aldehydes were deuterated at the alpha-position via a base-catalyzed exchange reaction with D2O. These deuterated building blocks were used for the synthesis of labelled analogues of quorum sensing signal molecules belonging to the three major ...
De Kimpe, Norbert +3 more
core +3 more sources
Pseudomonas cremoricolorata Strain ND07 Produces N-acyl Homoserine Lactones as Quorum Sensing Molecules [PDF]
Quorum sensing (QS) is a bacterial cell-to-cell communication system controlling QS-mediated genes which is synchronized with the population density. The regulation of specific gene activity is dependent on the signaling molecules produced, namely N-acyl
Nina Yusrina Muhamad Yunos +8 more
doaj +4 more sources
N-Acyl Homoserine Lactone Production by Klebsiella pneumoniae Isolated from Human Tongue Surface [PDF]
Bacteria communicate by producing quorum sensing molecules called autoinducers, which include autoinducer-1, an N-hexanoyl homoserine lactone (AHL), and autoinducer-2.
Kok-Gan Chan +6 more
doaj +4 more sources
Methods for Detecting N-Acyl Homoserine Lactone Production in Acinetobacter baumannii. [PDF]
Acinetobacter baumannii cell-cell signaling is mediated by production and release of N-acyl homoserine lactones (AHLs), primarily N-(3-hydroxydodecanoyl)-L-homoserine lactone (3-hydroxy-C12-HSL). The secretion of this signal can be readily assessed via simple plate-based or thin-layer chromatography-based assays utilizing an Agrobacterium tumefaciens ...
Paulk Tierney AR, Rather PN.
europepmc +4 more sources
N-Acyl Homoserine Lactone-Mediated Quorum Sensing Regulates Species Interactions in Multispecies Biofilm Communities. [PDF]
Bacterial biofilms are important medically, environmentally and industrially and there is a need to understand the processes that govern functional synergy and dynamics of species within biofilm communities. Here, we have used a model, mixed-species biofilm community comprised of Pseudomonas aeruginosa PAO1, Pseudomonas protegens Pf-5 and Klebsiella ...
Subramoni S +4 more
europepmc +6 more sources
A novel plasmid for detection of N-acyl homoserine lactones [PDF]
Many bacteria utilize acyl-homoserine lactones as cell to cell signals that can regulate the expression of numerous genes. Structural differences in acyl-homoserine lactones produced by different bacteria, such as acyl side chain length and the presence or absence of an oxy group, make many of the commonly used detection bioassays impractical for broad
Elizabeth A, Ling +2 more
openaire +2 more sources
Impact of N-Acyl-Homoserine Lactones, Quorum Sensing Molecules, on Gut Immunity [PDF]
Among numerous molecules found in the gut ecosystem, quorum sensing (QS) molecules represent an overlooked part that warrants highlighting. QS relies on the release of small molecules (auto-inducers) by bacteria that accumulate in the environment depending on bacterial cell density.
Garance Coquant +3 more
openaire +3 more sources
Many intercellular communication processes, known as quorum sensing (QS), are regulated by the autoinducers N-acyl-l-homoserine lactones (AHLs) in Gram-negative bacteria.
Lara Serrano-Aguirre +5 more
doaj +1 more source
Anti-Inflammatory Effects of Analogues of N-Acyl Homoserine Lactones on Eukaryotic Cells [PDF]
Background: Since acyl-homoserine lactone (AHL) profiling has been described in the gut of healthy subjects and patients with inflammatory bowel disease (IBD), the potential effects of these molecules on host cells have raised interest in the medical community.
Agathe Peyrottes +6 more
openaire +2 more sources

