Results 21 to 30 of about 13,538,908 (209)
N-Acyl Homoserine Lactone Analog Modulators of the Pseudomonas aeruginosa Rhll Quorum Sensing Signal Synthase. [PDF]
ACS Chem Biol, 2019 Virulence in the Gram-negative pathogen Pseudomonas aeruginosa relies in part on the efficient functioning of two LuxI/R dependent quorum sensing (QS) cascades, namely, the LasI/R and RhlI/R systems that generate and respond to N-(3-oxo)-dodecanoyl-l ...
Shin D +7 more
europepmc +2 more sources
Gac two-component system in Pseudomonas syringae pv. tabaci is required for virulence but not for hypersensitive reaction [PDF]
, 2008 Pseudomonas syringae pv. tabaci 6605 causes wildfire disease on host tobacco plants. To investigate the regulatory mechanism of the expression of virulence, Gac two-Component system-defective mutants, Delta gacA and Delta gacS, and a double mutant, Delta
Ichinose, Yuki +7 more
core +1 more source
Nicotinamide and Sodium Butyrate Double the Pool of Treatment-Exclusive Metabolites in the Endophytic Fungus Curvularia sp. G6-32. [PDF]
Chem BiodiversEpigenetic modulators nicotinamide and sodium butyrate reshape the chemical landscape of the endophytic fungus Curvularia sp. G6‐32. Combining the OSMAC strategy with UHPLC‐MS/MS metabolomics and molecular networking reveals a more than twofold rise in treatment‐exclusive metabolites, including diketopiperazines and potentially bioactive natural ...
Pega GEA +8 more
europepmc +2 more sources
Sensors, 2012 We report the production and degradation of quorum sensing N-acyl-homoserine lactones by bacteria isolated from Malaysian montane forest soil. Phylogenetic analysis indicated that these isolates clustered closely to the genera of Arthrobacter, Bacillus ...
Kok-Gan Chan +5 more
doaj +1 more source
Frontiers in Microbiology, 2020 Quorum quenching (QQ) is a promising strategy for preventing and controlling quorum sensing (QS)-mediated bacterial infections. It interferes with QS by the inhibition of signal synthesis, the detection of enzyme-catalyzed degradation, and the ...
Xinghui Fan +11 more
doaj +1 more source
Quorum sensing negatively regulates multinucleate cell formation during intracellular growth of Burkholderia pseudomallei in macrophage-like cells. [PDF]
PLoS ONE, 2013 Burkholderia pseudomallei is a Gram-negative environmental bacterium and the causative agent of melioidosis, a potentially fatal, acute or chronic disease endemic in the tropics.
Rachel E Horton +11 more
doaj +1 more source
Production of N-acyl Homoserine Lactones and Virulence Factors of Waterborne Aeromonas hydrophila [PDF]
Indian Journal of Microbiology, 2013 Aeromonads are inhabitants of aquatic ecosystems and are described as being involved in intestinal disturbances and other infections. The purpose of this study was to investigate the production of N-acyl-homoserine lactone (AHL) signal molecules and some virulence factors, including hemolysins, proteases, extracellular nucleases production and ...
Weihua, Chu +4 more
openaire +2 more sources
Quorum Sensing Activity in Pandoraea pnomenusa RB38
Sensors, 2014 Strain RB38 was recovered from a former dumping area in Malaysia. MALDI-TOF mass spectrometry and genomic analysis identified strain RB-38 as Pandoraea pnomenusa. Various biosensors confirmed its quorum sensing properties.
Robson Ee +4 more
doaj +1 more source
Microorganisms, 2020 Quorum sensing (QS) is a cell density-dependent mechanism that regulates the expression of specific genes in microbial cells. Quorum quenching (QQ) is a promising strategy for attenuating pathogenicity by interfering with the QS system of pathogens.
Wenping Zhang +8 more
doaj +1 more source
The Scientific World Journal, 2014 Many Proteobacteria communicate via production followed by response of quorum sensing molecules, namely, N-acyl homoserine lactones (AHLs). These molecules consist of a lactone moiety with N-acyl side chain with various chain lengths and degrees of ...
Kok-Gan Chan +4 more
doaj +1 more source