Rearrangement of N-acylated homoserine lactones into tetramic acids as algicidal agents
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Agrobacterium conjugation and gene regulation by N-acyl-L-homoserine lactones
Nature, 1993Conjugal opines secreted by crown gall tumours induce strains of Agrobacterium tumefaciens that are donors of Ti plasmids to produce a diffusible conjugation factor. This enhances the conjugal transfer efficiency of the Ti plasmid in other strains of A. tumefaciens.
L, Zhang +3 more
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N-Acyl Homoserine Lactone Mediating Initial Adhesion of Microalgal Biofilm Formation
SSRN Electronic Journal, 2023While pioneering methods have demonstrated that bacterial N-acyl homoserine lactone (AHL) signaling molecules can influence the growth and self-aggregation of suspended microalgae, whether AHLs can affect the initial adhesion to a carrier has remained an open question.
Zixuan Ou +9 more
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Molecular mechanisms of N‐acyl homoserine lactone signals perception by plants
Cell Biology International, 2021AbstractN‐acyl homoserine lactones (AHLs) belong to the class of bacterial quorum sensing signal molecules involved in distance signal transduction between Gram‐negative bacteria colonizers of the rhizosphere, as well as bacteria and plants. AHLs synchronize the activity of genes from individual cells, allowing the bacterial population to act as a ...
Lidia M. Babenko +2 more
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Thiourea-catalyzed aminolysis of N-acyl homoserine lactones
Chemical Communications, 2013Thiourea catalysts accelerate aminolysis of N-acyl homoserine lactones (AHLs), molecules integral to bacterial quorum sensing. The catalysts afford rate enhancement of up to 10 times the control in CD(3)CN. Mild catalysis in other polar aprotic solvents is still observed, while the activity is attenuated in polar protic solvents.
Michael A, Bertucci +2 more
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Solution structural features of N -acyl homoserine lactones
Tetrahedron Letters, 2015Here we demonstrate that in interbacterial quorum signal moderators, N-acylhomoserine lactones (AHLs), the stabilization of bioactive pharmacophore lactone against lysis is through the e(-) withdrawing N-acyl motif which reduces lactone carbonyl polarization. This lysis is assisted by weak (
Tumminakatti, Shama +4 more
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Imaging N-Acyl Homoserine Lactone Quorum Sensing In Vivo
2010In order to study N-acyl homoserine lactone (AHL)-based quorum sensing in vivo, we present a protocol using an Escherichia coli strain equipped with a luxR-based monitor system, which in the presence of exogenous AHL molecules expresses a green fluorescent protein (GFP).
Hultqvist, Louise Dahl +4 more
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Development and characterization of rat monoclonal antibodies for N-acylated homoserine lactones
Analytical and Bioanalytical Chemistry, 2010Quorum sensing (QS) is a communication mechanism between bacteria using diffusible chemical signaling molecules, which are called autoinducers (AI). By detecting the concentration of quorum sensing molecules through binding to a specific receptor protein, bacteria regulate their gene expressions when the concentration of autoinducers and thus the cell ...
Xiao, Chen +8 more
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QSAR MODEL OF THE QUORUM-QUENCHING N-ACYL-HOMOSERINE LACTONE LACTONASE ACTIVITY
Journal of Biological Systems, 2008A quantitative structure-activity relationship (QSAR) study was performed to model the lactonolysis activity of N-acyl-homoserine lactone lactonase. A data set comprising of 20 homoserine lactones and related compounds was taken from the work of Wang et al. Quantum chemical descriptors were calculated using the semiempirical AM1 method.
Nantasenamat, Chanin +5 more
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Selective transamidation of 3-oxo-N-acyl homoserine lactones by hydrazine derivatives
Org. Biomol. Chem., 2014Hydrazine derivatives are employed for selective amide cleavage of 3-oxo-N-acyl homoserine lactones under physiologically relevant conditions.
Michael A, Bertucci +2 more
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