Results 21 to 30 of about 3,735 (212)

Detection of N-acylhomoserine lactones in lung tissues of mice infected with Pseudomonas aeruginosa [PDF]

open access: bronzeMicrobiology, 2000
The pathogenesis of Pseudomonas aeruginosa is associated with expression of virulence factors, many of which are controlled by two N:-acylhomoserine lactone (AHL)-based quorum-sensing systems. Escherichia coli strains equipped with a luxR-based monitor system expressing green fluorescent protein (GFP) in the presence of exogenous AHL molecules were ...
Hong Wu   +10 more
openalex   +5 more sources

Inhibition of quorum sensing in Serratia marcescens AS-1 by synthetic analogs of N-acylhomoserine lactone. [PDF]

open access: greenAppl Environ Microbiol, 2007
Morohoshi T   +6 more
europepmc   +2 more sources

Direct detection ofN-acylhomoserine lactones in cystic fibrosis sputum [PDF]

open access: bronzeFEMS Microbiology Letters, 2002
Pseudomonas aeruginosa and Burkholderia cepacia cause destructive lung disease in cystic fibrosis (CF) patients. Both pathogens employ 'quorum sensing', i.e. cell-to-cell communication, via diffusible N-acyl-L-homoserine lactone (AHL) signal molecules, to regulate the production of a number of virulence determinants in vitro. However, to date, evidence
Barry Middleton   +5 more
  +5 more sources

The growth characteristics of algae in the presence of N-acylhomoserine lactones

open access: yesWater Supply, 2023
Abstract Algal–bacterial symbiotic system is ubiquitous in natural water and has an important impact on water quality and environment such as algal toxins from extracellular secretions. In general, the species diversity and abundance of this system can be dynamically regulated by quorum sensing (QS).
Yuankun Yang   +4 more
openaire   +2 more sources

Structure and Function of the α‐Hydroxylation Bimodule of the Mupirocin Polyketide Synthase

open access: yesAngewandte Chemie, Volume 135, Issue 47, November 20, 2023., 2023
Mupirocin is a clinically important polyketide antibiotic bearing a 6‐hydroxy group that is essential for biological activity. NMR spectroscopy, authentic synthetic substrates and mass spectrometry were used to establish the mechanistic steps governing incorporation of this key 6‐hydroxy group by an α‐hydroxylation bimodule that recruits a trans acting
Ashley J. Winter   +11 more
wiley   +2 more sources

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