Results 81 to 90 of about 3,713 (189)

N-Acylhomoserine lactone-dependent cell-to-cell communication and social behavior in the genus Serratia

International Journal of Medical Microbiology, 2006
Members of the genus Serratia are increasingly responsible for nosocomial infections, the treatment of which may be complicated by the appearance of multi-antibiotic-resistant strains. Some but not all Serratia strains and species produce N-acylhomoserine lactones (AHLs), and possess luxR and luxI homologous genes.
Jun-Rong, Wei, Hsin-Chih, Lai
openaire   +2 more sources

Synthesis, Cytotoxic Activity, Antiquorum Sensing Effect, Docking and Md Simulation of Novel 1,3‐Disubstituted 2‐Mercapto‐1H‐Benzo[D]Imidazolium Chlorides

Journal of Biochemical and Molecular Toxicology, Volume 39, Issue 4, April 2025.
A series of benzimidazolium chlorides and their 2‐mercapto were successfully synthesized and characterized. Cytotoxic activity assays revealed that certain synthesized compounds exhibited efficacy against cancer cell lines. To investigate the possible mechanism underlying their cytotoxic effects, the binding interactions of the three most active ...
Mohammad Mavvaji, Muhammed Tilahun Muhammed, Ebru Onem, Halime Güzin Aslan, Sadeq K. Alhag, Senem Akkoc   +5 more
wiley   +1 more source

Rice and bean AHL-mimic quorum-sensing signals specifically interfere with the capacity to form biofilms by plant-associated bacteria [PDF]

, 2013
Many bacteria regulate their gene expression in response to changes in their population density in a process called quorum sensing (QS), which involves communication between cells mediated by small diffusible signal molecules termed autoinducers.
Bellogín Izquierdo, Ramón Andrés, Contreras Sánchez-Matamoros, Rocío, Espuny Gómez, María del Rosario, Jiménez Guerrero, Irene, López Baena, Francisco Javier, Ollero Márquez, Francisco Javier, Pérez Montaño, Francisco de Asís, Rodríguez Carvajal, Miguel Ángel   +7 more
core   +1 more source

Biofilm formation in cardiovascular infection and bioengineering approaches for treatment and prevention

MedComm – Biomaterials and Applications, Volume 4, Issue 1, March 2025.
Biofilm‐related infections in cardiovascular system involve infective endocarditis, prosthetic heart valve endocarditis as well as cardiac device‐associated infections. There are still challenges remaining in the treatment of biofilm‐related infections in cardiovascular system.
Qi Tong, Qiyue Xu, Jie Cai, Yiren Sun, Zhengjie Wang, Yongjun Qian   +5 more
wiley   +1 more source

AidP, a novel N-Acyl Homoserine Lactonase gene from Antarctic Planococcus sp. [PDF]

, 2017
Planococcus is a Gram-positive halotolerant bacterial genus in the phylum Firmicutes, commonly found in various habitats in Antarctica. Quorum quenching (QQ) is the disruption of bacterial cell-to-cell communication (known as quorum sensing), which has ...
Chan, Kok-Gan, Convey, Peter, Ee, Robson, Lim, Yan-Lue, Pearce, David, See-Too, Wah Seng, Yin, Wai-Fong   +6 more
core   +2 more sources

Quercetin Exhibits Broad‐Spectrum Antibiofilm and Antiquorum Sensing Activities Against Gram‐Negative Bacteria: In Vitro and In Silico Investigation Targeting Antimicrobial Therapy

Canadian Journal of Infectious Diseases and Medical Microbiology, Volume 2025, Issue 1, 2025.
Quercetin (QC), a flavonoid abundant in fruits and vegetables, has garnered attention for its potential therapeutic properties. In this study, we investigated the antibiofilm and antiquorum sensing (QS) activities of QC against Gram‐negative bacteria both in vitro and in silico.
Tanvi Shastri, Reem Binsuwaidan, Arif Jamal Siddiqui, Riadh Badraoui, Sadaf Jahan, Nawaf Alshammari, Mohd Adnan, Mitesh Patel, Mahmoud Elhaig   +8 more
wiley   +1 more source

Infant‐Type Bifidobacteria as Biocontrol Agents: Suppressing Listeria monocytogenes via Key Virulence Gene Alteration

Canadian Journal of Infectious Diseases and Medical Microbiology, Volume 2025, Issue 1, 2025.
Infant‐type bifidobacteria exhibit potential as targeted biocontrol agents against Listeria monocytogenes infections. However, the strain‐specific antimicrobial efficacy and molecular mechanisms remain insufficiently characterized. In this study, the probiotic potential of five bifidobacteria strains was systematically evaluated through comprehensive ...
Qianglai Tan, Yiting Zheng, Lanlan Wu, Yanling Wang, Wanqian Xu, Muding Lin, Zhen Zeng, Arif Siddiqui   +7 more
wiley   +1 more source

Classifying the Topology of AHL-Driven Quorum Sensing Circuits in Proteobacterial Genomes

Sensors, 2012
Virulence and adaptability of many Gram-negative bacterial species are associated with an <em>N</em>-acylhomoserine lactone (AHL) gene regulation mechanism called quorum sensing (QS).
Sándor Pongor, Vittorio Venturi, Borisz Galbáts, Zsolt Gelencsér, Kumari Sonal Choudhary, Bruna Goncalves Coutinho, Sanjarbek Hudaiberdiev   +6 more
doaj   +1 more source

Evaluation of HPLC Profile, Antioxidant, Quorum Sensing, Biofilm, Swarming Motility, and Enzyme Inhibition Activities of Conventional and Green Extracts of Salvia triloba

Food Science &Nutrition, Volume 12, Issue 12, Page 10716-10733, December 2024.
The current study demonstrated the ability of the green solvent as a friendly solvent to extract phenolic compounds from Salvia triloba and evaluated their biological activities for the first time. ABSTRACT The current study aims to prepare a green extract using a new method in addition to conventional extraction methods including; methanolic and ...
Mohammed Mansour Quradha, Alfred Ngenge Tamfu, Mehmet Emin Duru, Selcuk Kucukaydin, Mudassar Iqbal, Abdulkader Moqbel Farhan Qahtan, Rasool Khan, Ozgur Ceylan   +7 more
wiley   +1 more source

N-acetylglucosamine inhibits LuxR, LasR and CviR based quorum sensing regulated gene expression levels

Frontiers in Microbiology, 2016
N-acetyl glucosamine, the monomer of chitin, is an abundant source of carbon and nitrogen in nature as it is the main component and breakdown product of many structural polymers. Some bacteria use N-acyl-L-homoserine lactone (AHL) mediated quorum sensing
Onder Kimyon, Zehra Ipek Uluturk, Shashidhar Nizalapur, Matthew Lee, Samuel K Kutty, Sabrina Beckmann, Naresh Kumar, Mike Manefield   +7 more
doaj   +1 more source