Results 151 to 160 of about 155,572 (257)

Characterization and immunogenicity of nanoparticle vaccines displaying embecovirus spike proteins

open access: yesBiotechnology Progress, EarlyView.
Virus‐like particle vaccines displaying spike proteins from OC43, HKU1 A, and HKU1 B were evaluated in mice for their ability to elicit antibodies against the spike proteins from OC43, HKU1 A, HKU1 B, and HKU1 C. Abstract Endemic human coronaviruses OC43 and HKU1 cause widespread respiratory infections and can be associated with severe illness in ...
Peter J. Halfmann   +6 more
wiley   +1 more source

Quantitative Modeling of IgG N-Glycosylation Profiles from Population Data. [PDF]

open access: yesInt J Mol Sci
Kutumova E   +7 more
europepmc   +1 more source

Advanced glucose control strategies leveraging Raman spectroscopy for optimized mammalian cell culture manufacturing

open access: yesBiotechnology Progress, EarlyView.
Abstract Maintaining consistent quality in the manufacturing of biotherapeutic proteins in mammalian cell culture is challenging, with unplanned deviations causing inconsistencies and potential batch failure. Current methods for monitoring and controlling critical process parameters (CPPs) rely on slow, labor‐intensive offline analyses.
Matthew Banner   +12 more
wiley   +1 more source

Screening of bispecific antibodies during single cell cloning of recombinant Chinese hamster ovary cell lines to improve titer and product quality

open access: yesBiotechnology Progress, EarlyView.
Abstract Development of therapeutic bispecific antibodies (BsAbs) poses significant manufacturability challenges associated with correct chain pairing and an increased diversity of impurities. Here we address this with a product quality assessment during cell line development (CLD), forgoing the need for genetic characterization during cell line ...
Molly Robinson   +7 more
wiley   +1 more source

Genetic variability, N-glycosylation, and recombination in sublineage 1A of <i>Betaarterivirus americense</i> from commercial pig farms in Lima, 2019. [PDF]

open access: yesFront Microbiol
Cotaquispe Nalvarte RY   +12 more
europepmc   +1 more source

Comprehensive Peptide Profiling Reveals the Influence of Streptococcus Thermophilus, Lactobacillus Delbrueckii Subsp. bulgaricus, and Endogenous Milk Proteases on the Hydrolysis of Milk Proteins During Early‐Stage Lactic Acid Fermentation

open access: yesChemFoodChem, EarlyView.
Untargeted peptide profiling investigates how S. thermophilus, Lb. bulgaricus, and endogenous milk enzymes impact proteolysis during early‐stage milk fermentation. ≥ 3000 identified peptides show the strongest influence of LB on the peptide profile and number of bioactive peptides. Shorter peptides are mostly formed by LB and hydrolyzed by ST.
Eva Beck   +6 more
wiley   +1 more source

In situ Generation of Fluoride Catalysts for CO2‐to‐Formic Acid Conversion With Silicon Reducing Agent

open access: yesChemistry – A European Journal, EarlyView.
Reductive conversion of CO2 to formic acid with waste silicon reducing agent catalyzed by in situ generation of active fluoride species from a tertiary amine, protonic acid, and simple inorganic fluoride salt, such as KF and NaF. ABSTRACT The activation and catalytic reduction of carbon dioxide (CO2) using silicon‐based reducing agents is an important ...
S. M. A. Hakim Siddiki   +6 more
wiley   +1 more source

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