Results 191 to 200 of about 151,535 (246)

Novel Laboratory Approaches in Heavy Chain Disease With Discordant Immunoglobulin Quantitation: A Case Report and Literature Review

Journal of Clinical Laboratory Analysis, EarlyView.
In this study, we investigated a rare case of γ‐heavy chain disease (γ‐HCD) through an integrated laboratory approach. Routine protein analyses (serum protein electrophoresis, immunotyping, and serum/urine immunofixation) identified an IgG monoclonal component without detectable light chains.
Eleonora Longhi, Artan Çeka, Fabiola Olivieri, Marco Moretti, Jacopo Sabbatinelli   +4 more
wiley   +1 more source

Comparative Analysis of Serum N-Glycosylation in Endometriosis and Gynecologic Cancers. [PDF]

Int J Mol Sci
Pásztor R, Viskolcz B, Oláh C, Váradi C.   +3 more
europepmc   +1 more source

Mixed‐mode membrane chromatography: mechanistic‐modeling‐based optimization and scale‐up of antibody charge variant separation using a novel membrane adsorber

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Efficient manufacturing of complex biopharmaceuticals increasingly relies on innovative downstream processing strategies. Membrane chromatography offers a promising alternative to resin‐based systems by enabling high‐throughput separations at elevated flow rates. Typically used in flow‐through mode, its industrial applications range
Jan Hedrich, Rita Steigmiller, Viktor Simaev, Romas Skudas, Michael Schulte, Mathias Hafner, Christian Frech   +6 more
wiley   +1 more source

Phosphomannomutase 2-congenital disorder of glycosylation: exploring the role of N-glycosylation on the endocrine axes. [PDF]

Front Endocrinol (Lausanne)
Del Medico G, Ferri L, Procopio E, Annibalini G, Barbieri E, Barone R, Guerrini R, Morrone A, Stagi S.   +8 more
europepmc   +1 more source

Optimization of bioactive compounds extraction from Rosa canina L. pseudofruit through the action of two hydrolytic enzyme preparations

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKROUND The pseudo‐fruit of Rosa canina L. is a rich source of bioactive compounds with antioxidant, anti‐inflammatory, anti‐cancer, anti‐diabetic, anti‐aging, and antimicrobial activities. The aim of the present study is the optimization of a green process based on the action of two hydrolytic enzyme preparations, namely Pectinex® Ultra ...
Zafeiria Lemoni, Styliani Kalantzi, Theopisti Lymperopoulou, Andromachi Tzani, Georgios Stavropoulos, Anastasia Detsi, Diomi Mamma   +6 more
wiley   +1 more source

N-glycosylation patterns of plasma immunoglobulin G in anti-synthetase syndrome disease. [PDF]

Front Immunol
Zhao J, Li Y, Ling Y, Wu T, Wu Y, Tan C, Cheng L, Huang D, Liu Y, Zhang Y.   +9 more
europepmc   +1 more source

Usefulness of Gamma‐Glutamyl Transferase and Sequential Carbohydrate‐Deficient Transferrin for Unhealthy Alcohol Use Screening in Indigenous Communities

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Unhealthy alcohol use (UAU) screening facilitates identification of patients with alcohol use problems for intervention. This study evaluates the usefulness of gamma‐glutamyl transferase (GGT) and sequential percentage of carbohydrate‐deficient transferrin (%CDT) in community screening for UAU.
Jing‐Houng Wang, Hui‐Min Tien, Hsiao‐Chu Lien, Pei‐Lin Chou, Yu‐Ling Chen, Nien‐Tzu Hsu, Sheng‐Nan Lu   +6 more
wiley   +1 more source

Ligand preference of EphB2 receptor is selectively regulated by N-glycosylation. [PDF]

iScience
Lyu C, Yuan L, Yang Y, Zhang D, Hu W, Zhao K, Ding Y, Chen W, Xiao K, Chen Y, Liu W.   +10 more
europepmc   +1 more source

Diacetylene‐Functionalized Glycan Mimetics for Receptor‐Mediated Cluster Imprinting in Model Membranes

Macromolecular Rapid Communications, EarlyView.
Diacetylene‐containing glycan mimetics cluster upon selective lectin binding in GUVs. Subsequent irradiation leads to the formation of fluorescent polymer clusters, while non‐clustered glycan mimetics remain unaffected in the membrane. ABSTRACT The glycocalyx, a dense layer of glycoproteins and glycolipids on eukaryotic cells, is essential for cellular
Luca‐Cesare Blawitzki, Lina Charlotte Assenmacher, Nicholas Jäck, Stephan Schmidt, Cornelia Monzel, Laura Hartmann   +5 more
wiley   +1 more source

A hypomorphic Mpi mutation unlocks an in vivo tool for studying global N-glycosylation deficiency. [PDF]

JCI Insight
Lin EB, Meregini S, Zhang Z, Roy A, Argula T, Mitchell JM, Israelsen WJ, Ludwig S, Russell J, Quan J, Hildebrand S, Nair-Gill E, Beutler B, SoRelle JA.   +13 more
europepmc   +1 more source