Results 1 to 10 of about 1,679 (80)

The glycosyltransferase UGT76B1 modulates N-hydroxy-pipecolic acid homeostasis and plant immunity. [PDF]

Plant Cell, 2021
Abstract The tradeoff between growth and defense is a critical aspect of plant immunity. Therefore, the plant immune response needs to be tightly regulated. Salicylic acid (SA) is an important plant hormone regulating defense against biotrophic pathogens. Recently, N-hydroxy-pipecolic acid (NHP) was identified as another regulator for
Mohnike L, Rekhter D, Huang W, Feussner K, Tian H, Herrfurth C, Zhang Y, Feussner I.   +7 more
europepmc   +15 more sources

Regulation of Salicylic Acid and N-Hydroxy-Pipecolic Acid in Systemic Acquired Resistance [PDF]

The Plant Pathology Journal, 2023
In plants, salicylic acid (SA) is a central immune signal that is involved in both local and systemic acquired resistance (SAR). In addition to SA, several other chemical signals are also involved in SAR and these include N-hydroxy-pipecolic acid (NHP ...
Gah-Hyun Lim
doaj   +4 more sources

An Artificial Pathway for N-Hydroxy-Pipecolic Acid Production From L-Lysine in Escherichia coli [PDF]

Frontiers in Microbiology, 2022
N-hydroxy-pipecolic acid (NHP) is a hydroxylated product of pipecolic acid and an important systemic acquired resistance signal molecule. However, the biosynthesis of NHP does not have a natural metabolic pathway in microorganisms.
Zhou Luo, Zhen Wang, Bangxu Wang, Yao Lu, Lixiu Yan, Zhiping Zhao, Ting Bai, Jiamin Zhang, Hanmei Li, Wei Wang, Jie Cheng   +10 more
doaj   +5 more sources

N-Hydroxy pipecolic acid methyl ester is involved in Arabidopsis immunity. [PDF]

J Exp Bot, 2023
Abstract The biosynthesis of N -hydroxy pipecolic acid (NHP) has been intensively studied, though knowledge on its metabolic turnover is still scarce. To close this gap, we discovered three novel metabolites via metabolite fingerprinting in Arabidopsis thaliana
Mohnike L, Huang W, Worbs B, Feussner K, Zhang Y, Feussner I.   +5 more
europepmc   +5 more sources

A NAC triad modulates plant immunity by negatively regulating N-hydroxy pipecolic acid biosynthesis [PDF]

Nature Communications
N-hydroxy pipecolic acid (NHP) plays an important role in plant immunity. In contrast to its biosynthesis, our current knowledge with respect to the transcriptional regulation of the NHP pathway is limited.
Jianghua Cai, Sayantan Panda, Yana Kazachkova, Eden Amzallag, Zhengguo Li, Sagit Meir, Ilana Rogachev, Asaph Aharoni   +7 more
doaj   +4 more sources

N-hydroxy-pipecolic acid-mediated signal transduction and resistance requires DAWDLE. [PDF]

Plant Physiol
Abstract Plant systemic acquired resistance (SAR) is a pathogen-induced, long-distance immune response that primes uninfected tissue against future pathogen attacks. N-hydroxy-pipecolic acid (NHP) is a mobile signal required to initiate and amplify SAR signaling in different plant species.
Hsu JK, Hsieh HY, Huang CH, Hsieh CY, Ou JY, Huang SF, Hung ET, Liu YC, Cheng SC, Lin YC, Chen YC.   +10 more
europepmc   +3 more sources

An engineered pathway for <i>N</i>-hydroxy-pipecolic acid synthesis enhances systemic acquired resistance in tomato. [PDF]

Sci Signal, 2019
Engineering a metabolite biosynthesis pathway in crop plants enhances systemic acquired resistance to pathogens.
Holmes EC, Chen YC, Sattely ES, Mudgett MB.   +3 more
europepmc   +4 more sources

N-hydroxy-pipecolic acid is a mobile metabolite that induces systemic disease resistance in Arabidopsis. [PDF]

Proc Natl Acad Sci U S A, 2018
Significance Plants lack circulating immune cells and instead rely on small molecule chemistry for local and long-distance defense signaling. Following pathogen attack, plants activate innate immune pathways at the site of infection to limit pathogen growth.
Chen YC, Holmes EC, Rajniak J, Kim JG, Tang S, Fischer CR, Mudgett MB, Sattely ES.   +7 more
europepmc   +4 more sources

Transcriptome analysis reveals role of transcription factor WRKY70 in early N-hydroxy-pipecolic acid signaling. [PDF]

Plant Physiol
Abstract N-Hydroxy-pipecolic acid (NHP) is a mobile metabolite essential for inducing and amplifying systemic acquired resistance (SAR) following a pathogen attack. Early phases of NHP signaling leading to immunity have remained elusive.
Foret J, Kim JG, Sattely ES, Mudgett MB.
europepmc   +3 more sources

Agmatine and N-hydroxypipecolic acid synergistically enhance salt tolerance in wheat through antioxidant defense, proline metabolism, and photosynthetic protection [PDF]

Plant Signaling & Behavior
Salt stress severely limits wheat growth by disturbing photosynthesis, osmotic balance, and cellular redox homeostasis. This study evaluated whether agmatine and N-hydroxy pipecolic acid, applied alone or in combination, could improve wheat tolerance ...
Ghulam Murtaza, Oybek Mamarakhimov, Khasan Musaev, Mamlakat Djabbarova, Lola Sanayeva, Negmurod Rashidov, Khayrullo Ibragimov, Sajad Ali, Mohammed S. Alotaibi, Aziza Huseynova, Nazih Y. Rebouh, Sajid Ullah, Rashid Iqbal   +12 more
doaj   +2 more sources