A Simple and Highly Sensitive HPLC Method with Fluorescent Detection for Determination of Pipecolic Acid in Mouse Brain Areas [PDF]
A simple and highly sensitive high-performance liquid chromatography method for the determination of pipecolic acid in mouse brain areas was developed. After homogenization of brain and pretreatment with o-phthalaldehyde, the pipecolic acid and (2S,3S)-3-
9000270162760 +23 more
core +1 more source
LURP1, a SARD1-regulated protein, coordinates with the helper NLR ADR1 to promote plant immunity. [PDF]
The working model of LURP1 function in plant immunity. Upon pathogen infection, SARD1/CBP60g promotes the transcription of LURP1 directly. LURP1 likely functions as an adaptor protein that associates with the PRRs–BAK1 complexes at the plasma membrane (PM) while also interacts with the ADR1 family helper NLRs.
Liu X +7 more
europepmc +2 more sources
Crystal structure of (1R,4R)-tert-butyl 3-oxo-2-oxa-5-azabicyclo[2.2.2]octane-5-carboxylate
In the title compound, C11H17NO4, commonly known as N-tert-butoxycarbonyl-5-hydroxy-d-pipecolic acid lactone, the absolute configuration is (1R,4R) due to the enantiomeric purity of the starting material which remains unchanged during the course of the ...
Suvratha Krishnamurthy +4 more
doaj +1 more source
Pipecolic acid in plants: biosynthesis, signalling, and role under stress
Plants protect themselves by developing defensive responses against various biotic and abiotic stress factors throughout their lives. As a result, they create a stress response called ʻsystemic acquired resistance’ (SAR) under pathogen infection ...
Fatma Nur Koc, Burcu Seckin Dinler
doaj +1 more source
Metabolic profiling framework for discovery of candidate diagnostic markers of malaria [PDF]
Despite immense efforts to combat malaria in tropical and sub-tropical regions, the potency of this vector-borne disease and its status as a major driver of morbidity and mortality remain undisputed.
Utzinger, Juerg +8 more
core +1 more source
Effects of ursodeoxycholic acid on synthesis of cholesterol and bile acids in healthy subjects [PDF]
Background/Aims: Ursodeoxycholic acid ( UDCA) decreases biliary secretion of cholesterol and is therefore used for the dissolution of cholesterol gallstones.
Thiessen, K. +5 more
core +1 more source
The plastidial exporter Enhanced Disease Susceptibility 5 is required for the biosynthesis of N -hydroxy pipecolic acid [PDF]
Abstract Pipecolic acid is essential for the establishment of systemic acquired resistance in plants. It is synthesized in the plastid and further processed in the cytosol to its active form N-hydroxy pipecolic acid. Here we provide strong evidence that the exporter Enhanced Disease Susceptibility 5 is required for the biosynthesis of ...
Rekhter, Dmitrij +5 more
openaire +2 more sources
Conservation of N -hydroxy-pipecolic acid-mediated systemic acquired resistance in crop plants [PDF]
SUMMARY Signal propagation and the coordination of whole-organism responses in plants rely heavily on small molecules. Systemic acquired resistance (SAR) is one such process in which long-distance signaling activates immune responses in uninfected tissue as a way to limit the spread of a primary, localized infection ...
Holmes, Eric C. +3 more
openaire +1 more source
Golubev A, Sewald N, Burger K. An Efficient Approach to the Family of 4-Substituted Pipecolic Acids. Syntheses of 4-Oxo, cis-4-Hydroxy-, and trans-4-Hydroxy-L-pipecolic Acids from L-Aspartic Acid. Tetrahedron Letters.
Burger, Klaus +2 more
core +1 more source
A stereoselective synthesis of N-Boc-protected cis-(2R,3S)-3-hydroxy pipecolic acid, starting from d-glucose is described. The key step in the overall synthesis is a highly regioselective reductive cleavage of benzylidene acetal 13 leading to ...
Kumar, Ponminor Senthil +1 more
core +1 more source

