The use of prodrugs as drugs of abuse
WIREs Forensic Science, Volume 6, Issue 3, May/June 2024.Metabolism transforms inactive drugs (prodrugs) into active drugs. Abstract Prodrugs are an important strategy for the development and design of therapeutic drugs. They involve the addition of an easily removable group (such as an ester) to a molecule in order to chemically protect it from metabolism, hydrolysis, or interaction with tissues.
Julio de Carvalho Ponce
wiley +1 more source
A systematic review of income and education reporting in psychedelic clinical trials [PDF]
Socioeconomic status (SES) substantially influences mental health outcomes and treatment access, yet its reporting in psychedelic-assisted therapy trials remains underexplored.
Anderson, Brian T +6 more
core +1 more source
Psicosis en la adolescencia: abuso del consumo de sustancias y papel de enfermería [PDF]
, 2022 Aproximadamente 275 millones de personas en todo el mundo consumieron drogas de abuso durante el último año, siendo el cannabis la más consumida y a más temprana edad.
Gil Ros, Raquel +1 more
core
What works for whom and why:A narrative systematic review of interventions for reducing post-traumatic stress disorder and problematic substance use among women with experiences of interpersonal violence [PDF]
, 2019 Background and aimsWomen with histories of interpersonal violence (IPV) experience high levels of post-traumatic stress disorder (PTSD), problematic substance use, and repeat victimization.
Bailey, Karen +2 more
core +2 more sources
Serotonin receptors and heart valve disease—It was meant 2B [PDF]
, 2011 Carcinoid heart disease was one of the first valvular pathologies studied in molecular detail, and early research identified serotonin produced by oncogenic enterochromaffin cells as the likely culprit in causing changes in heart valve tissue ...
Hutcheson, Joshua D. +3 more
core +2 more sources
Perspectives and preliminary experiences of psychedelics for the treatment of eating disorders: A systematic scoping review. [PDF]
OBJECTIVE: Research regarding the therapeutic application of psychedelics and psychedelic-assisted psychotherapy in the treatment of eating disorders (EDs) has begun to emerge.
Cuerva, A +4 more
core +1 more source
Efecto del malato de pizotifeno sobre el metabolismo oxidativo de cerebro de rata "in vitro" [PDF]
, 2012 El malato de pizotifeno es un fármaco antihistamínico H1, antiserotonínico, débilmente anticolinérgico y aperitivo. Se emplea fundamentalmente en la profilaxis de la jaqueca o migraña.
García Catalina, Sara
core +2 more sources
Eficácia e segurança do uso de alucinógenos no tratamento de transtornos de humor : uma revisão sistemática de revisões sistemáticas [PDF]
Orientador: Prof. Drª. Inajara RottaCoorientador: Prof. Drª. Jaqueline CarneiroMonografia (graduação) - Universidade Federal do Paraná, Setor de Ciências da Saúde, Curso de Graduação em FarmáciaInclui referênciasResumo : Os transtornos de humor são ...
Ikeda, Celeste Miyuki Nagase
core
Applications of MDMA in Modern Medicine - A Literature Review [PDF]
MDMA or 3,4- methylenedioxymethamphetamine is a psychoactive substance, exhibiting mild hallucinogenic properties, that became widely known as a recreational party drug.
Dudziak, Piotr +10 more
core +1 more source