Results 221 to 230 of about 111,646 (306)
The Role of Neuropeptide Y in Dental Pulp: Balancing Neurogenic Inflammation and Pain Modulation
International Endodontic Journal, EarlyView.ABSTRACT Background Dental pulp is a densely innervated, low‐compliance tissue in which neurogenic inflammation can rapidly escalate into oedema, raised intrapulpal pressure, microvascular compromise, and pain. While Substance P (SP) and Calcitonin gene‐related peptide (CGRP) are well‐established drivers of pulp vasodilation, the Neuroopeptide Y (NPY ...
Javier Caviedes‐Bucheli +3 more
wiley +1 more source
Agmatine preferentially antagonizes GluN2B-containing N-methyl-d-aspartate receptors in spinal cord.
J Neurophysiol, 2019 Waataja JJ +7 more
europepmc +1 more source
Oral Diseases, EarlyView.ABSTRACT Objective This systematic review and meta‐analysis aimed to evaluate the most effective minimally invasive intra‐articular procedure for reducing pain and improving maximum mouth opening (MMO) in individuals diagnosed with painful articular TMD, specifically TMJ osteoarthritis and/or internal derangement.
Mateus Gaya dos Santos +5 more
wiley +1 more source
Psychiatry and Clinical Neurosciences, EarlyView.Aim To determine the smallest worthwhile difference (SWD) for lecanemab, a disease‐modifying drug for Alzheimer's disease (AD), among the general Japanese population using a benefit‐harm trade‐off method. Methods We conducted an online survey with 658 participants to evaluate their preferences for the treatment effect of lecanemab, given its associated
Aran Tajika +5 more
wiley +1 more source
Of mice and men—The emerging oral–gut–brain axis of health and disease
Periodontology 2000, EarlyView.Abstract Objectives Oral health's inextricable links to systemic health are highlighted by the emerging oral–gut–brain axis and other well‐known axes. There is growing evidence of a complex oral–gut–brain axis linking mouth and gut microbiomes with the central nervous system.
Yvonne L. Hernandez‐Kapila +1 more
wiley +1 more source
Perceptual Priors Update Contextual Feedback Processing in V1
Topics in Cognitive Science, EarlyView.Abstract Contextual information and prior knowledge facilitate perceptual processing, improving our recognition of even distorted or obstructed visual inputs. As a result, neuronal processing elicited by identical sensory inputs varies depending on the context in which we encounter those inputs.
Yulia Y. Lazarova +3 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend The genetic inactivation of one Mcu allele leads to sex‐specific changes in neuronal function in adult mice, that is, the firing of action potentials and the relationship between cytosolic and mitochondrial Ca2+ levels. The ability to produce NAD(P)H by stimulated neural tissue is largely preserved in male mice but delayed in ...
Jenna Gray +16 more
wiley +1 more source
Deciphering pro‐arrhythmogenic mechanisms of EPAC in human atrial cardiomyocytes
The Journal of Physiology, EarlyView.Abstract figure legend This study aimed to investigate the effect of exchange proteins directly activated by cAMP (EPAC) on the regulation of human atrial cardiomyocyte electrophysiology and their potential involvement in the onset of atrial fibrillation (AF).
Arthur Boileve +11 more
wiley +1 more source
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N-Methyl-D-Aspartate Receptors
The Oxford Handbook of Neuronal Ion Channels, 2018Discovered more than 70 years ago due to advances in electrophysiology and cell culture techniques, N-methyl-D-aspartate (NMDA) receptors remain the target of assiduous basic and clinical research.
G. Iacobucci, G. Popescu
semanticscholar +1 more source