Results 71 to 80 of about 12,056 (230)

Risk Assessment Models for Heated Tobacco Products

Risk Analysis, Volume 46, Issue 8, August 2026.
ABSTRACT Heated tobacco products (HTPs) are marketed as alternatives to conventional cigarettes with a potential reduced risk profile. Yet, their actual impact on cancer and noncancer disease risk remains uncertain and requires rigorous quantitative assessment.
Lucia Maddalena, Beril Yildiz, Francesca Del Vecchio Blanco, Mario Rosario Guarracino   +3 more
wiley   +1 more source

Quantum chemical calculations of nitrosamine activation and deactivation pathways for carcinogenicity risk assessment

Frontiers in Pharmacology
N-nitrosamines and nitrosamine drug substance related impurities (NDSRIs) became a critical topic for the development and safety of small molecule medicines following the withdrawal of various pharmaceutical products from the market.
Andreas H. Göller, Sandra Johanssen, Adam Zalewski, Verena Ziegler   +3 more
doaj   +1 more source

The impact of tobacco cessation on buccal mucosa cancer risk: A multi‐centre case–control study in India

International Journal of Cancer, Volume 159, Issue 2, Page 368-377, 15 July 2026.
What's new? While the association between tobacco consumption and oral cancer is well established, the effect of cessation, particularly of chewing tobacco, the most common tobacco product in South Asia, is understudied. This case–control study in an Indian population demonstrates that a longer duration of tobacco smoking and chewing cessation is ...
Gayathri B. Pullat, Bastian Bohrmann, Grace Sarah George, Shubham Dikshit, Arjun Singh, Pankaj Chaturvedi, Rajesh Dikshit, Sarah Lewington, Sharayu Mhatre   +8 more
wiley   +1 more source

Nitrosamines crisis in pharmaceuticals − Insights on toxicological implications, root causes and risk assessment: A systematic review

Journal of Pharmaceutical Analysis
The presence of N-nitroso compounds, particularly N-nitrosamines, in pharmaceutical products has raised global safety concerns due to their significant genotoxic and mutagenic effects.
Hemanth P.R. Vikram, Tegginamath Pramod Kumar, Gunjan Kumar, Narasimha M. Beeraka, Rajashree Deka, Sheik Mohammed Suhail, Sandeep Jat, Namitha Bannimath, Gayatiri Padmanabhan, Ravandur S. Chandan, Pramod Kumar, Bannimath Gurupadayya   +11 more
doaj   +1 more source

Risk assessment of chemical substances of safety concern generated in processed meats

Food Science and Human Wellness, 2019
This manuscript is reviewing the presence of substances of safety concern that may be generated in different types of meat products. Such substances include N-nitrosamines that can be generated under certain conditions when using nitrite as preservative,
Mónica Flores, Leticia Mora, Milagro Reig, Fidel Toldrá   +3 more
doaj   +1 more source

Formation of N-nitrosamines from seconday animes and nitrite by resting cells of Escherichia coli B [PDF]

, 1979
Naomichi KUNISAKI, Makoto Hayashi
openalex   +1 more source

Analysis and risk assessment of nitrosamines in sartans using GC-MS and Monte Carlo simulation

Scientific Reports
The precise detection of nitrosamines at very low levels in various substances is crucial because of their known toxicity and potential to cause genetic mutations.
Fatemeh Shomali, Zahra Talebpour, Ghazaleh Abedi, Nilufar Mousavi, Shiva Mokhtarifar, Marjan Kohandani, Vahideh Mahdavi, Noushin Adib   +7 more
doaj   +1 more source

Overview and justification of a toxicological experiment design for establishing risk assessment indicators

Tạp chí Kiểm nghiệm và An toàn thực phẩm
N-nitrosamines in food products are a serious health threat due to their carcinogenic and non-carcinogenic effects on the kidneys, spleen, GIT, and liver. Meat products are a major source of their exposure. Within a joint Russian-Vietnamese study, health
Nina V. Zaitseva, Pavel Z. Shur, Dmitry V. Suvorov, Sergey E. Zelenkin   +3 more
doaj   +1 more source

A Survey of N-nitrosamines in Namhan River and Natural Solar Photolysis of N-nitrosamines

Journal of Environmental Analysis, Health and Toxicology
This study aimed to evaluate the impact of sunlight on the behavior of N-nitrosamines in the Jugdangcheon stream, a tributary of the Namhan River. N-nitrosamines were monitored over four occasions in 2024, and experiments were conducted to investigate their decomposition under natural sunlight, considering variables such as radiation intensity and ...
In Ja Lee, Min Hee Lee, Woo Hyun Yoon, Do Il Chang, Hyun Seong Chang   +4 more
openaire   +1 more source

Effect of food products on endogenous generation of n−nitrosamines in rats [PDF]

, 1997
V. K. Atanasova-Goranova, P Dimova, Galina Pevicharova   +2 more
openalex   +1 more source