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Urethane and N-nitrosodiethylamine are mutagenic for the Syrian hamster fetus
Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2008Urethane and N-nitrosodiethylamine are soluble environmental carcinogens that initiate tumors transplacentally, but have a mixed history of effectiveness in mutagenesis assays in vitro or in vivo with adult rodents. To test for their transplacental mutagenicity, Syrian hamster fetuses at 12 days in gestation were exposed transplacentally to urethane or
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