Results 201 to 210 of about 28,700 (263)

Analysis of N6-Methyladenosine Modification Patterns and Tumor Immune Microenvironment in Pancreatic Adenocarcinoma

open access: gold, 2022
Yong Liu   +6 more
openalex   +1 more source

m6A RNA Modification Controls HTLV‐1 Tax and Host Gene Expression

open access: yesGenes to Cells, Volume 30, Issue 6, November 2025.
Our study shows that m6A regulation is critical for controlling HTLV‐1, shaping both viral transcripts and host gene programs, thereby illuminating latency mechanisms and suggesting tractable targets for therapy and prevention. ABSTRACT Human T‐cell Leukemia Virus Type 1 (HTLV‐1) is a pathogenic human retrovirus that is responsible for intractable ...
Rei Gibu   +5 more
wiley   +1 more source

Unveiling the Role of circRNAs in Pyroptotic Signalling: From Molecular Crosstalk to Disease Modulation

open access: yesJournal of Cellular and Molecular Medicine, Volume 29, Issue 22, November 2025.
ABSTRACT Pyroptosis is a gasdermins‐dependent programmed cell death (PCD) characterised by progressive cellular swelling and plasma membrane rupture (PMR). This process releases intracellular contents that amplify inflammatory cascades and immune activation, involving the pathogenesis of various disorders such as tumours, heart and vascular diseases ...
Tengyu Jin   +4 more
wiley   +1 more source

NSUN2‐mediated m5C methylation modification regulates trophoblast cell proliferation, apoptosis, and autophagy in gestational diabetes mellitus

open access: yesJournal of Diabetes Investigation, Volume 16, Issue 11, Page 2005-2017, November 2025.
ABSTRACT Introduction Gestational diabetes mellitus (GDM) represents one of the most prevalent medical complications during pregnancy. Emerging evidence has implicated NOL1/NOP2/SUN domain (NSUN)2‐mediated 5‐methylcytosine (m5C) methylation modifications in various pathological conditions. This study aimed to investigate the role of m5C modification in
Jiujiu Liu   +3 more
wiley   +1 more source

METTL3 Reduces Oxidative Stress-induced Apoptosis in Presbycusis by Regulating the N6-methyladenosine Level of SIRT1 mRNA

open access: hybrid, 2023
Enhao Wang   +9 more
openalex   +1 more source

RNA Granules at the Crossroads of Synaptic Dysfunction and Neurodegeneration

open access: yesJournal of Neurochemistry, Volume 169, Issue 11, November 2025.
Under physiological conditions, neuronal RNA granules (e.g., transport granules, activity‐dependent granules, processing bodies, and stress granules) cooperate to regulate mRNA transport, storage, and localized translation, thereby sustaining synaptic and neuronal functions.
Rita Nóbrega‐Martins   +5 more
wiley   +1 more source

N6-methyladenosine methylation: a novel key to unlocking mental disorders. [PDF]

open access: yesInt J Neuropsychopharmacol
Wang Y   +6 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy