Results 181 to 190 of about 20,108 (223)

N6-methyladenosine RNA landscape in the aged mouse hearts. [PDF]

Front Cardiovasc Med
Jing X, Li Y, Liao Z, Wu JY, Xu ZY, Yang ZP, Mo HL, Xu S, Liu X, Wu Z, Tao J, Xiong XD.   +11 more
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N6-methyladenosine methylation: a novel key to unlocking mental disorders. [PDF]

Int J Neuropsychopharmacol
Wang Y, Li X, Liu M, Xu X, Ma Y, Luo Y, Wang Y.   +6 more
europepmc   +1 more source

N6-methyladenosine improves porcine longissimus dorsi muscle quality by regulating myofiber differentiation. [PDF]

BMC Genomics
Yin C, Yang S, Huang Y, Zhou Z, Huang J, Yang B, Huang L.   +6 more
europepmc   +1 more source

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N6-methyladenosine and Neurological Diseases

Molecular Neurobiology, 2022
N6-methyladenosine (m6A) is a dynamic reversible methylation modification of the adenosine N6 position and is the most common chemical epigenetic modification among mRNA post-transcriptional modifications, including methylation, demethylation, and recognition.
Nan Zhang, Chunhong Ding, Yuxin Zuo, Yu Peng, Lielian Zuo   +4 more
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The evolution of N6-methyladenosine regulators in plants

Methods, 2022
As a reversible modification, N6-methyladenosine (m6A) plays key roles in series of biological processes. Although it has been found that m6A modification is regulated by writers, erasers and readers, their evolutionary processes are still not clearly and systematically described. In the present work, we identified 1592 m6A modification regulators from
Meng, Wu, Fulei, Nie, Haibin, Liu, Tianyang, Zhang, Miaomiao, Li, Xiaoming, Song, Wei, Chen   +6 more
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N6-Methyladenosine Modifications in Pulmonary Hypertension

Pharmacology, 2023
<b><i>Background:</i></b> The most prevalent kind of RNA methylation modification existing in eukaryotes is N6-methyladenosine (m6A), which is a reversible type of posttranscriptional modification. <b><i>Summary:</i></b> Many studies have reported that m6A participates in cell differentiation, self ...
Yu, Xia, Yanyan, Zhang, Jie, Huang, Bing, Chen, YanJiao, Jiang, Zengxian, Sun, Yun, Liu   +6 more
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N6-Methyladenosine in the Heart

2021
Similar to DNA modifications, an epitranscriptome of mRNA modifications emerged over the last few years in the cardiovascular system. Specifically, the discovery of the N6-methyladenosine (m6A) as reversible post-transcriptional modification in mRNAs raised recent interest in those modifications in cardiomyocytes and their role in diseased hearts.
Vivien Kmietczyk, Ellen Malovrh, Mirko Völkers   +2 more
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N6‐methyladenosine (m6A) Modification in Preeclampsia

Reproductive Sciences, 2023
Recently, epitranscriptional modification of N6-methyladenosine (m6A) has received growing attention in the research on the pathogenesis of preeclampsia. Advances in m6A sequencing have revealed the molecular mechanism and importance of m6A modification.
Tingting Zhang, Ziyan Jiang, Nana Yang, Zhiping Ge, Qing Zuo, Shiyun Huang, Lizhou Sun   +6 more
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N6-methyladenosine–encoded epitranscriptomics

Nature Structural & Molecular Biology, 2016
N6-methyladenosine (m6A) is the most abundant internal modification in eukaryotic mRNA. Recent discoveries of the locations, functions and mechanisms of m6A have shed light on a new layer of gene regulation at the RNA level, giving rise to the field of m6A epitranscriptomics. In this Perspective, we provide an update on the various effects of mammalian
Nian, Liu, Tao, Pan
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N6-Methyladenosine Methylation of mRNA in Cell Senescence

Cellular and Molecular Neurobiology, 2021
Cell senescence is the growth arrest caused by the accumulation of irreparable cell damage, which is involved in physiological and pathological processes and regulated by the post-transcriptional level. This regulation is performed by transcriptional regulators and driven by aging-related small RNAs, long non-coding RNAs, and RNA-binding proteins.
Lin Zhang, Jian Xia
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