Results 11 to 20 of about 326,728 (258)

Naïve T Cells in Immunosuppression Diseases: Human Immunodeficiency Virus and Cytomegalovirus

MCBS (Molecular and Cellular Biomedical Sciences), 2018
Dynamic changes of naïve T cells determine mature T cells activity in cell-mediated immune response. It is important to understand the mechanism of homeostasis maintenance affect response to novel antigen toward T cell receptor-major histocompatibility ...
Sandra, Ferry, Setiawan, Kent Wijaya, Ferry Sandra, Kent Wijaya Setiawan   +3 more
core   +3 more sources

Identification and Characterization of Circulating Naïve CD4+ and CD8+ T Cells Recognizing Nickel

Frontiers in Immunology, 2019
Allergic contact dermatitis caused by contact sensitizers is a T-cell-mediated inflammatory skin disease. The most prevalent contact allergens is nickel.
Pollastro, Sabrina, de Vries, Niek, Bechara, Rami, Maillère, Bernard, Pallardy, Marc, Azoury, Marie Eliane, Szely, Natacha   +6 more
core   +2 more sources

Sepsis leads to lasting changes in phenotype and function of naïve CD8 T cells.

PLoS Pathogens, 2023
Sepsis, an amplified immune response to systemic infection, is characterized by a transient cytokine storm followed by chronic immune dysfunction. Consequently, sepsis survivors are highly susceptible to newly introduced infections, suggesting sepsis can
Gail A Bishop, Thomas S Griffith, Vladimir P Badovinac, Roger R Berton, Isaac J Jensen, John T Harty, Patrick W McGonagil, Tiffany K Ybarra   +7 more
core   +2 more sources

Naive T Cells in Graft Versus Host Disease and Graft Versus Leukemia: Innocent or Guilty? [PDF]

Front Immunol, 2022
The outcome of allogeneic hematopoietic cell transplantation (allo-HCT) largely depends on the development and management of graft-versus-host disease (GvHD), infections, and the occurrence of relapse of malignancies.
Dekker L, Sanders E, Lindemans CA, de Koning C, Nierkens S.   +4 more
europepmc   +2 more sources

Selective depletion of naïve T cells by targeting CD45RA. [PDF]

Front Oncol, 2022
Naik S, Triplett BM.
europepmc   +2 more sources

Age-Related Gene Alteration in Naïve and Memory T cells Using Precise Age-Tracking Model

Frontiers in Cell and Developmental Biology, 2021
In aged individuals, age-related changes in immune cells, especially T cell deficiency, are associated with an increased incidence of infection, tumor, and autoimmune disease, as well as an impaired response to vaccination.
Xiaofeng Yang, Xiaofeng Yang, Xiaofeng Yang, Xin Wang, Xin Wang, Xin Wang, Lei Lei, Lei Lei, Lei Lei, Lina Sun, Lina Sun, Anjun Jiao, Anjun Jiao, Anjun Jiao, Kun Zhu, Kun Zhu, Tao Xie, Tao Xie, Haiyan Liu, Haiyan Liu, Xingzhe Zhang, Xingzhe Zhang, Yanhong Su, Yanhong Su, Cangang Zhang, Cangang Zhang, Lin Shi, Lin Shi, Dan Zhang, Dan Zhang, Huiqiang Zheng, Huiqiang Zheng, Jiahui Zhang, Jiahui Zhang, Xiaobin Liu, Xiaobin Liu, Xin Wang, Xin Wang, Xiaobo Zhou, Xiaobo Zhou, Chenming Sun, Chenming Sun, Baojun Zhang, Baojun Zhang, Baojun Zhang   +44 more
doaj   +1 more source

Metabolic changes in naïve and polyclonal activated T-cell from naive mice [PDF]

Egyptian Journal of Cancer and Biomedical Research, 2018
We have found previously that early activated T cells show higher activities and antitumor effects than late activated T cells upon their adoptive transfer. However, the exact mechanism is not clear.
Mona Hegazi, Tarek Mohamed, Mohamed Salem, Asmaa Eltaramsy   +3 more
doaj   +1 more source

Effect of LncRNA XIST on Immune Cells of Primary Biliary Cholangitis

Frontiers in Immunology, 2022
ObjectivePrimary biliary cholangitis (PBC) is an autoimmune disease with significant gender difference. X chromosome inactivation (XCI) plays important roles in susceptibility to diseases between genders.
Chunhui She, Yifei Yang, Bo Zang, Yuan Yao, Qixuan Liu, Patrick S. C. Leung, Bin Liu   +6 more
doaj   +1 more source

TRIB2 safeguards naive T cell homeostasis during aging

Cell Reports, 2023
Summary: Naive CD4+ T cells are more resistant to age-related loss than naive CD8+ T cells, suggesting mechanisms that preferentially protect naive CD4+ T cells during aging.
Wenqiang Cao, Ines Sturmlechner, Huimin Zhang, Jun Jin, Bin Hu, Rohit R. Jadhav, Fengqin Fang, Cornelia M. Weyand, Jörg J. Goronzy   +8 more
doaj   +1 more source

Activated-memory T cells influence naïve T cell fate: a noncytotoxic function of human CD8 T cells

Communications Biology, 2022
Human activated memory CD8 T cells develop a non-cytotoxic function and influence the fate of autologous naïve CD8 T cells where they acquire an activated/memory state and a hybrid state between naïve and activated memory.
Kazuki Sasaki, Mouhamad Al Moussawy, Khodor I. Abou-Daya, Camila Macedo, Amira Hosni-Ahmed, Silvia Liu, Mariam Juya, Alan F. Zahorchak, Diana M. Metes, Angus W. Thomson, Fadi G. Lakkis, Hossam A. Abdelsamed   +11 more
doaj   +1 more source