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Activators of α7 nAChR as Potential Therapeutics for Cognitive Impairment
2020The α7 nicotinic acetylcholine receptor (nAChR) is a promising target for the treatment of cognitive deficits associated with psychiatric and neurological disorders, including schizophrenia and Alzheimer's disease (AD). Several α7 nAChR agonists and positive allosteric modulators (PAMs) have demonstrated procognitive effects in preclinical models and ...
Jason M. Uslaner +2 more
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Localization of nAChR subunit mRNAs in the brain of Macaca mulatta
European Journal of Neuroscience, 2000AbstractWe present here a systematic mapping of nAChR subunit mRNAs in Macaca mulatta brain. A fragment, from the transmembrane segments MIII to MIV of Macaca neuronal nAChR subunits was cloned, and shown to exhibit high identity (around 95%) to the corresponding human subunits.
Michele Zoli +7 more
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Spiro-Trycyclic Alkaloids as nAChR Antagonists
Synfacts, 2021Dirk Trauner, Bruno Matos Paz
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Regulation of nAChR expression: Posttranscriptional regulation of nAChRs
2023openaire +1 more source
Editors' note: Astron. Nachr. 5/2008
Astronomische Nachrichten, 2008Michael Thompson +2 more
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nAChR mutations involved in insecticide resistance
2016 International Congress of Entomology, 2016openaire +2 more sources
The insect neuronal nAChR: a homo-oligomer or not?
Trends in Neurosciences, 1987openaire +2 more sources