Results 21 to 30 of about 2,824 (121)
Nicotinic α7 acetylcholine receptor-mediated currents are not modulated by the tryptophan metabolite kynurenic acid in adult hippocampal interneurons [PDF]
The tryptophan metabolite, kynurenic acid (KYNA), is classically known to be an antagonist of ionotropic glutamate receptors. Within the last decade several reports have been published suggesting that KYNA also blocks nicotinic acetylcholine receptors (nAChRs) containing the \alpha7 subunit (\alpha7*).
arxiv +1 more source
Anti-solar differential rotation [PDF]
The differential rotation of anti-solar type detected by observations for several stars may result from a fast meridional flow. The sufficiently intensive meridional circulation may be caused by large-scale thermal inhomogeneities or, perhaps, by tidal forcing from a companion star.
arxiv +1 more source
Differential rotation on the lower main sequence [PDF]
We compute the differential rotation of main sequence stars of the spectral types F, G, K, and M by solving the equation of motion and the equation of convective heat transport in a mean-field formulation. For each spectral type the rotation rate is varied to study the dependence of the surface shear on this parameter.
arxiv +1 more source
Subspace foliations and collapse of closed flat manifolds [PDF]
We study relations between certain totally geodesic foliations of a closed flat manifold and its collapsed Gromov-Hausdorff limits. Our main results explicitly identify such collapsed limits as flat orbifolds, and provide algebraic and geometric criteria to determine whether they are singular.
arxiv +1 more source
The Roles of a5-Containing nAChRs in the Brain [PDF]
Neuronal nicotinic acetylcholine receptors (nAChRs) are in the superfamily of the ligand-gated ion channels with an assembly of five subunits (a, bi subunit). nAChRs, such as a4b-and a7-nAChRs play crucial roles in nicotine reward, dependence and withdrawal.
Ming Gao, Jie Wu, Yakun Wang
openaire +2 more sources
Effect of the radiative background flux in convection [PDF]
Numerical simulations of turbulent stratified convection are used to study models with approximately the same convective flux, but different radiative fluxes. As the radiative flux is decreased, for constant convective flux: the entropy jump at the top of the convection zone becomes steeper, the temperature fluctuations increase and the velocity ...
arxiv +1 more source
Relativistic blue- and red-shifted absorption lines in AGNs [PDF]
Current, accumulating evidence for (mildly) relativistic blue- and red-shifted absorption lines in AGNs is reviewed. XMM-Newton and Chandra sensitive X-ray observations are starting to probe not only the kinematics (velocity) but also the dynamics (accelerations) of highly ionized gas flowing in-and-out from, likely, a few gravitational radii from the ...
arxiv +1 more source
Neuronal nAChR stereoselectivity to non‐natural epibatidine derivatives [PDF]
The frog toxin epibatidine is one of the most powerful ligands of the neuronal nicotinic receptors and derivatives show promising possibilities for labeling in positron emission tomography studies. In an attempt to reduce epibatidine toxicity, new methyl derivatives were synthesized, tested in positron emission tomography imaging and in ...
Gerrit Westera+5 more
openaire +3 more sources
The Newtonian limit of fourth and higher order gravity [PDF]
We consider the Newtonian limit of the theory based on the Lagrangian L = R + \sum a_k R \Box^k R. The gravitational potential of a point mass turns out to be a combination of Newtonian and Yukawa terms. For sixth-order gravity the coefficients are calculated explicitly.
arxiv +1 more source
NMR structures of the transmembrane domains of the α4β2 nAChR
The α4β2 nicotinic acetylcholine receptor (nAChR) is the predominant heteromeric subtype of nAChRs in the brain, which has been implicated in numerous neurological conditions. The structural information specifically for the α4β2 and other neuronal nAChRs is presently limited.
Pei Tang+6 more
openaire +3 more sources