Results 51 to 60 of about 76,340 (268)
The distribution of charged amino acid residues and the Ca(2+) permeability of nicotinic acetylcholine receptors: a predictive model [PDF]
, 2017 Nicotinic acetylcholine receptors (nAChRs) are cation-selective ligand-gated ion channels exhibiting variable Ca(2+) permeability depending on their subunit composition.
Fucile, Sergio
core +1 more source
Neuropsychopharmacology, 2017 Understanding why the quit rate among smokers of menthol cigarettes is lower than non-menthol smokers requires identifying the neurons that are altered by nicotine, menthol, and acetylcholine. Dopaminergic (DA) neurons in the ventral tegmental area (VTA)
Brandon J. Henderson +5 more
semanticscholar +1 more source
Bounded geometry and leaves [PDF]
, 2016 The main theorem states that any complete connected Riemannian manifold of bounded geometry can be isometrically realized as a leaf with trivial holonomy in a compact Riemannian foliated space.Comment: 21 pages. To appear in Math. Nachr. arXiv admin note:
Lijó, Ramón Barral +1 more
core +2 more sources
Marine Drugs, 2020 The α9-containing nicotinic acetylcholine receptor (nAChR) is increasingly emerging as a new tumor target owing to its high expression specificity in breast cancer. αO-Conotoxin GeXIVA is a potent antagonist of α9α10 nAChR.
Zhihua Sun +5 more
doaj +1 more source
Oxidative Medicine and Cellular Longevity, 2019 Background Cardiomyocyte apoptosis is critical for the development of coxsackievirus B3- (CVB3-) induced myocarditis, which is a common cardiac disease that may result in heart failure or even sudden death.
Pi-Hong Li +9 more
semanticscholar +1 more source
A G protein‐coupled α7 nicotinic receptor regulates signaling and TNF‐α release in microglia
FEBS Open Bio, 2017 Acetylcholine activation of α7 nicotinic acetylcholine receptors (α7 nAChRs) in microglia attenuates neuroinflammation and regulates TNF‐α release. We used lipopolysaccharide to model inflammation in the microglial cell line EOC20 and examined signaling ...
Justin R. King +2 more
doaj +1 more source
The nicotinic receptor of cochlear hair cells: A possible pharmacotherapeutic target? [PDF]
, 2009 Mechanosensory hair cells of the organ of Corti transmit information regarding sound to the central nervous system by way of peripheral afferent neurons.
Elgoyhen, Ana Belen +2 more
core +1 more source
Cell Discovery, 2017 Vagal circuits-α7 nAChR (α7 nicotinic acetylcholine receptor, coded by Chrna7) signaling utilizes spleen as a hub to dampen systemic inflammatory responses. Vagal innervations also extend to the distal airways and alveoli.
Caiqi Zhao +6 more
semanticscholar +1 more source
A continuation principle for a class of periodically perturbed autonomous systems
, 2007 In this paper we evaluate the topological index of periodic solutions otained via the Malkin-Loud bifurcation result. Incidentally, we do not assume that the perturbation is differentiale.Comment: Accepted to Math. Nachr., Vol. 281, (2008), No.
Kamenskii, Mikhail +2 more
core +2 more sources
Skeletal Editing from Pyridine to Aniline via C‐Insertion and N‐Isomerization
ChemistryEurope, EarlyView.A concise protocol is presented that converts pyridines into anilines by externalizing the original pyridine nitrogen at either the "ipso" or "ortho" position, which results in para or meta‐primary aniline products. A key carbene‐insertion step precedes nitrogen migration, preserving both ring size and overall structure.
Yun Luo +3 more
wiley +1 more source