Results 1 to 10 of about 968,543 (216)

CycloZ Improves Hyperglycemia and Lipid Metabolism by Modulating Lysine Acetylation in KK-Ay Mice [PDF]

Diabetes & Metabolism Journal, 2023
Background CycloZ, a combination of cyclo-His-Pro and zinc, has anti-diabetic activity. However, its exact mode of action remains to be elucidated.
Jongsu Jeon, Dohyun Lee, Bobae Kim, Bo-Yoon Park, Chang Joo Oh, Min-Ji Kim, Jae-Han Jeon, In-Kyu Lee, Onyu Park, Seoyeong Baek, Chae Won Lim, Dongryeol Ryu, Sungsoon Fang, Johan Auwerx, Kyong-Tai Kim, Hoe-Yune Jung   +15 more
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Conceptual framework for SARS-CoV-2–related lymphopenia

Advanced Biomedical Research, 2022
The emerging of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak is associated with high morbidity and mortality rates globally. One of the most prominent characteristics of coronavirus disease-19 (COVID-19) is lymphopenia, which is ...
Ilnaz Rahimmanesh, Shirin Kouhpayeh, Yadollah Azizi, Hossein Khanahmad   +3 more
doaj   +1 more source

Mitochondrial dysfunction at the cornerstone of inflammatory exacerbation in aged macrophages

Exploration of Immunology, 2023
Immunosenescence encompasses multiple age-related adaptations that result in increased susceptibility to infections, chronic inflammatory disorders, and higher mortality risk.
Rafael Moura Maurmann, Brenda Landvoigt Schmitt, Negin Mosalmanzadeh , Brandt D. Pence   +3 more
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CD38 in Neurodegeneration and Neuroinflammation

Cells, 2020
Neurodegenerative diseases are characterized by neuronal degeneration as well as neuroinflammation. While CD38 is strongly expressed in brain cells including neurons, astrocytes as well as microglial cells, the role played by CD38 in neurodegeneration ...
Serge Guerreiro, Anne-Laure Privat, Laurence Bressac, Damien Toulorge   +3 more
doaj   +1 more source

The investigation of the effect of NAD, H2O2 and weak magnetic field on the antibacterial mechanism of isoniazid (INH) that first line antibiotic against M. tuberculosis agent

Medicine Science, 2020
Tuberculosis is an infectious disease, which is caused by the Mycobacterium tuberculosis complex. This disease leads to up to 1.3 million deaths out of more than eight million cases every year.
Selami Gunal, Kadir Batcioglu, Esra Erdogan   +2 more
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Enfermedad del coronavirus (covid-19) y las sirtuinas

Revista de la Facultad de Ciencias Médicas de Córdoba, 2020
Las  proteínas desacetilasas dependientes del NAD+, se denominan Sirtuinas (SIRT). Objetivos: estudiar las sirtuinas involucradas en el cáncer, así como los estudios de inhibición de SIRT1 en pacientes con la enfermedad del coronavirus COVID-19 ...
Ronald Eleazar Huarachi Olivera, Antonio Lazarte Rivera   +1 more
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Investigation of sand in piping [PDF]

Zbornik Matice Srpske za Prirodne Nauke, 2012
For the investigation of the grain size distribution of the material washed out from the piping, we used 20 samples originating from different places on the Danube and the Tisza rivers.
Nađ Laslo
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Sirtuins in the pathogenetic therapy of neurodegenerative diseases [PDF]

Клиническая практика
The progressive decline in the physiological functions during aging leads to various diseases that place a heavy burden on patients, their families and the society as a whole.
Ekaterina M. Samoilova, Alina A. Ivanova, Petr P. Laktionov, Vladimir A. Kalsin, Stanislav E. Romanov   +4 more
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Characterization of sand boils with grading entropy [PDF]

Zbornik Matice Srpske za Prirodne Nauke, 2012
Grain size and grain distribution by size are dominant factors determining soil behaviour. The shape and position of a grain distribution curve contain implicit information about the propensity of sand boiling or piping at flood conditions. The author
Nađ Laslo
doaj   +1 more source

The essential schistosome tegumental ectoenzyme SmNPP5 can block NAD-induced T cell apoptosis

Virulence, 2020
Infection with intravascular platyhelminths of the genus Schistosoma can result in the debilitating disease schistosomiasis. Schistosomes (blood flukes) can survive in the host for many years.
Catherine S. Nation, Akram A. Da’Dara, Patrick J. Skelly   +2 more
doaj   +1 more source