Results 1 to 10 of about 178,109 (161)
CycloZ Improves Hyperglycemia and Lipid Metabolism by Modulating Lysine Acetylation in KK-Ay Mice [PDF]
Background CycloZ, a combination of cyclo-His-Pro and zinc, has anti-diabetic activity. However, its exact mode of action remains to be elucidated.
Jongsu Jeon +15 more
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Conceptual framework for SARS-CoV-2–related lymphopenia
The emerging of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak is associated with high morbidity and mortality rates globally. One of the most prominent characteristics of coronavirus disease-19 (COVID-19) is lymphopenia, which is ...
Ilnaz Rahimmanesh +3 more
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Textile pattern design is a challenging task that can be hardly resolved by a single deep neural network, due to the requirements on high resolution, periodic tiling, copyright protection and aesthetic preference of designers. In this paper, we present our NAD system which can automatically produce high-quality textile patterns for printing industry ...
Zhifei Pang +4 more
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Mitochondrial dysfunction at the cornerstone of inflammatory exacerbation in aged macrophages
Immunosenescence encompasses multiple age-related adaptations that result in increased susceptibility to infections, chronic inflammatory disorders, and higher mortality risk.
Rafael Moura Maurmann +3 more
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Enfermedad del coronavirus (covid-19) y las sirtuinas
Las proteínas desacetilasas dependientes del NAD+, se denominan Sirtuinas (SIRT). Objetivos: estudiar las sirtuinas involucradas en el cáncer, así como los estudios de inhibición de SIRT1 en pacientes con la enfermedad del coronavirus COVID-19 ...
Ronald Eleazar Huarachi Olivera +1 more
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CD38 in Neurodegeneration and Neuroinflammation
Neurodegenerative diseases are characterized by neuronal degeneration as well as neuroinflammation. While CD38 is strongly expressed in brain cells including neurons, astrocytes as well as microglial cells, the role played by CD38 in neurodegeneration ...
Serge Guerreiro +3 more
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Tuberculosis is an infectious disease, which is caused by the Mycobacterium tuberculosis complex. This disease leads to up to 1.3 million deaths out of more than eight million cases every year.
Selami Gunal +2 more
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Investigation of sand in piping [PDF]
For the investigation of the grain size distribution of the material washed out from the piping, we used 20 samples originating from different places on the Danube and the Tisza rivers.
Nađ Laslo
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Characterization of sand boils with grading entropy [PDF]
Grain size and grain distribution by size are dominant factors determining soil behaviour. The shape and position of a grain distribution curve contain implicit information about the propensity of sand boiling or piping at flood conditions. The author
Nađ Laslo
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NAD+ and its metabolites serve important functions in intracellular signalling. NAD+-mediated regulatory processes also take place on the cell surface, particularly of immune cells. In this issue of the Biochemical Journal, Gerth et al. have demonstrated a new mechanism of Ca2+ uptake into monocytes which is triggered by NAD+ or its degradation product,
Mathias, Ziegler, Marc, Niere
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