Neurological-related proteomic profiling in plasma of children with metabolic healthy and unhealthy overweight/obesity [PDF]
Pediatric Obesity, Volume 19, Issue 9, September 2024.Objective: Children with overweight/obesity (OW/OB) exhibit poor cardiometabolic health, yet mechanisms influencing brain health remain unclear. We examined the dif- ferences in neurological-related circulating proteins in plasma among children with ...
Olvera-Rojas, Marcos +4 more
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Localization and Regulation of Two NAD Nucleosidases in Ehrlich Ascites Cells [PDF]
European Journal of Biochemistry, 1968 After differential centrifugation of Ehrlich ascites cells by the de Duve method, NAD nuclosidase activities were found in the nuclear and the microsomal fractions, but not in the lysosomal fraction. The nuclear NAD nucleosidase is inhibited 50% by 0.2 mM nicotinamide and is highly specific for β-NAD.
K. W. Bock +4 more
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NAD(P) hydrolyzing enzymes in skipjack liver. I. Purification of NAD(P) nucleosidase. [PDF]
NIPPON SUISAN GAKKAISHI, 1976 A mixture of the three hydrolases, NAD(P) nucleosidase, nucleotide pyrophosphatase, and alkaline phosphatase, participating in the first step of the NAD(P) decomposition, was separated from skipjack liver. By Sephadex G-100 gel filtration, NAD(P) nucleosidase was successfully isolated from the mixture. During the gel filtration, the enzyme was found to
Hiroki ABE +2 more
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Structure and stereochemistry of the base excision repair glycosylase MutY reveal a mechanism similar to retaining glycosidases. [PDF]
, 2015 MutY adenine glycosylases prevent DNA mutations by excising adenine from promutagenic 8-oxo-7,8-dihydroguanine (OG):A mismatches. Here, we describe structural features of the MutY active site bound to an azaribose transition state analog which indicate a
Cao, Sheng +6 more
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Role of urate, xanthine oxidase and the effects of allopurinol in vascular oxidative stress [PDF]
, 2009 Oxidative stress plays an important role in the progression of vascular endothelial dysfunction. The two major systems generating vascular oxidative stress are the NADPH oxidase and the xanthine oxidase pathways. Allopurinol, a xanthine oxidase inhibitor,
George, Jacob, Struthers, Allan D.
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Functional Disorders of the Brain Induced by Synthesis of Nucleotides Containing 3-Acetylpyridine [PDF]
, 1968 Peer ...
HERKEN, H.
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Enzymes of ammonia assimilation and ureide biogenesis in developing pigeonpea (Cajanus cajan L.) nodules [PDF]
, 1985 Ammonia assimilatory and ureide biogenic enzymes were measured in the cytosol fraction of pigeonpea nodules during the period 15-120 days after sowing. The activity of enzymes involved in the initial assimilation of ammonia, i.e.
Amarjit,, Singh, Randhir
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Ureide biogenesis and the enzymes of ammonia assimilation and ureide biosynthesis in nitrogen fixing pigeonpea (Cajanus cajan) nodules [PDF]
, 1984 Allantoic acid production from IMP, XMP, inosine, xanthosine, hypoxanthine, xanthine, uric acid and allantoin was investigated by incubating each of these substrates withCajanus cajan cytosol and bacteroid fractions separately in the presence and absence
Amarjit,, Singh, Randhir
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Methylation deficiency disrupts biological rhythms from bacteria to humans [PDF]
, 2020 メチル化と体内時計が生命誕生以来の密な関係にあることを発見 --生命の起源に学ぶヒト障害の新治療法--. 京都大学プレスリリース. 2020-05-27.The methyl cycle is a universal metabolic pathway providing methyl groups for the methylation of nuclei acids and proteins, regulating all aspects of cellular physiology.
Cargill, Sam +25 more
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Influence of Dielectric Environment upon Isotope Effects onGlycoside Heterolysis: Computational Evaluation and AtomicHessian Analysis [PDF]
, 2019 Isotope effects depend upon the polarity of the bulk medium in which a chemical process occurs. Implicit solvent calculations with molecule-shaped cavities show that the equilibrium isotope effect (EIE) for heterolysis of the glycosidic bonds in 5 ...
Porter, Alexander J. +3 more
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